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GENE：MUC16

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MUC16
FullNmae mucin 16, cell surface associated
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15582
EnsembleID ENSG00000181143
Uniprot Q8WXI7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MUC16 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MUC16 GO:0005515,GO:0005796,GO:0005886,GO:0007155,GO:0009897,GO:0031982,GO:0070062

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LGALS3 MUC16 12615972 19556244 23180781 physical association pull down InnateDB
LGALS1 MUC16 12615972 23180781 physical association pull down InnateDB
MUC16 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 MUC16 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MUC16 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 MUC16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MUC16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MUC16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MUC16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MUC16 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
RAD21 MUC16 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM2 MUC16 25348397 N/A physical interaction ComPPI
UBC MUC16 25348397 N/A physical interaction ComPPI
EGFR MUC16 25348397 N/A physical interaction ComPPI
IGBP1 MUC16 25348397 N/A physical interaction ComPPI
TRIM25 MUC16 25348397 N/A physical interaction ComPPI
LGALS1 MUC16 12615972 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
MSLN MUC16 14525934 14676194 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
MUC16 NANOGP8 25348397 N/A physical interaction ComPPI
MUC16 NANOG 25348397 N/A physical interaction ComPPI
MUC16 POU5F1 25348397 N/A physical interaction ComPPI
MUC16 CEP170P1 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct

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