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GENE：PCSK1N

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PCSK1N
FullNmae proprotein convertase subtilisin/kexin type 1 inhibitor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17301
EnsembleID ENSG00000102109
Uniprot Q9UHG2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PCSK1N immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PCSK1N GO:0002021,GO:0004866,GO:0004867,GO:0005102,GO:0005615,GO:0005802,GO:0007218,GO:0009409,GO:0016486,GO:0030141

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PCSK1N CREB1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB
LYL1 PCSK1N 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PCSK1N 11799066 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF PCSK1N 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PCSK1N 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PCSK1N 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000001EB3 PCSK1N 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RAD51 PCSK1N 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ADCYAP1 PCSK1N 25348397 N/A physical interaction ComPPI
MMP10 PCSK1N 25348397 N/A physical interaction ComPPI
PCSK1 PCSK1N 11435430 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
ST3GAL4 PCSK1N 25348397 N/A physical interaction ComPPI
PCSK1N ADAM21 25348397 N/A physical interaction ComPPI
PCSK1N MGAT4C 25348397 N/A physical interaction ComPPI
PCSK1N DKKL1 25348397 N/A physical interaction ComPPI

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