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GENE：PDXK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDXK
FullNmae pyridoxal kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8819
EnsembleID ENSG00000160209
Uniprot O00764

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDXK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PDXK ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PDXK GO:0000287,GO:0005524,GO:0005576,GO:0005634,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0008270,GO:0008478,GO:0008478,GO:0008478,GO:0009443,GO:0009443,GO:0009443,GO:0009443,GO:0016310,GO:0030170,GO:0030955,GO:0031402,GO:0031403,GO:0034774,GO:0035580,GO:0042803,GO:0042817,GO:0042818,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PDXK hsa:8566 path:hsa00750 Vitamin B6 metabolism - Homo sapiens (human)
PDXK hsa:8566 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PDXK hsa:8566 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PDXK 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 PDXK 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PDXK 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PDXK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 PDXK 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000512C88 PDXK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE PDXK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PDXK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000081E1F PDXK 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B PDXK 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D PDXK 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F PDXK 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 PDXK 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 PDXK 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000170CF4 PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005ACA7C PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EED18 PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002C7B2B PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001F5B39 PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003758F0 PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075AEA5 PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049FAE8 PDXK 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GABARAPL2 PDXK 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3B PDXK 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COPS5 PDXK 25348397 N/A physical interaction ComPPI
CUL3 PDXK 25348397 N/A physical interaction ComPPI
YWHAZ PDXK 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
SNX2 PDXK 25348397 N/A physical interaction ComPPI
HNRNPL PDXK 25348397 N/A physical interaction ComPPI
CFTR PDXK 25348397 N/A physical interaction ComPPI
YWHAQ PDXK 25348397 N/A physical interaction ComPPI
TPI1 PDXK 25348397 N/A physical interaction ComPPI
CUL1 PDXK 25348397 N/A physical interaction ComPPI
OGT PDXK 25348397 N/A physical interaction ComPPI
GABARAP PDXK 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3A PDXK 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CAND1 PDXK 25348397 N/A physical interaction ComPPI
BARD1 PDXK 25348397 N/A physical interaction ComPPI
ELAVL1 PDXK 25348397 N/A physical interaction ComPPI
EIF4E PDXK 25348397 N/A physical interaction ComPPI
SOD1 PDXK 25348397 N/A physical interaction ComPPI
OAT PDXK 25348397 N/A physical interaction ComPPI
PRKAB1 PDXK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKE PDXK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EZR PDXK 25348397 N/A physical interaction ComPPI
G6PD PDXK 25348397 N/A physical interaction ComPPI
ATOH1 PDXK 25348397 N/A physical interaction ComPPI
NXF1 PDXK 25348397 N/A physical interaction ComPPI
MOV10 PDXK 25348397 N/A physical interaction ComPPI
HIBADH PDXK 25348397 N/A physical interaction ComPPI

Visualization










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