GENE：PLAC8
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PLAC8 |
| FullNmae | placenta associated 8 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:19254 |
| EnsembleID | ENSG00000145287 |
| Uniprot | Q9NZF1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PLAC8 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PLAC8 | GO:0003682,GO:0005576,GO:0006366,GO:0008284,GO:0009409,GO:0035578,GO:0040015,GO:0042742,GO:0043066,GO:0045944,GO:0050873,GO:0120162 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PLAC8 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | PLAC8 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | PLAC8 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | PLAC8 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | PLAC8 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PLAC8 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | PLAC8 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | PLAC8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00004CCA62 | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003ABC4 | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AF715 | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005485E8 | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076995 | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028FD1A | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CCD18 | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AD2AA | PLAC8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | PLAC8 | 25416803 27643556 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RBPMS | PLAC8 | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| PLAC8 | TRIP13 | 14525934 16189514 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| PLAC8 | COPS5 | 18624398 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PLAC8 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |