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GENE：PNP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PNP
FullNmae purine nucleoside phosphorylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7892
EnsembleID ENSG00000198805
Uniprot P00491

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PNP immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PNP GO:0000255,GO:0001882,GO:0002060,GO:0004731,GO:0004731,GO:0005515,GO:0005576,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006139,GO:0006148,GO:0006149,GO:0006157,GO:0006166,GO:0006204,GO:0006738,GO:0006955,GO:0009165,GO:0009410,GO:0032743,GO:0034418,GO:0034774,GO:0042102,GO:0042301,GO:0042802,GO:0043101,GO:0046059,GO:0046638,GO:0047975,GO:0070062,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PNP hsa:4860 path:hsa00230 Purine metabolism - Homo sapiens (human)
PNP hsa:4860 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
PNP hsa:4860 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PNP hsa:4860 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYC PNP 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 PNP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PNP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PNP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PNP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PNP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PNP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PNP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PNP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 PNP 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000002103A PNP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000ECE9C PNP 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004F859B PNP 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CF056 PNP 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PNP APLP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PNP ZHX1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PNP TFAM 12068295 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PNP TP53 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PNP UCHL5 25348397 N/A physical interaction ComPPI
PNP SIRT7 25348397 N/A physical interaction ComPPI
PNP CDK2 25348397 N/A physical interaction ComPPI
PNP DNAJB11 25348397 N/A physical interaction ComPPI
PNP NDUFV1 25348397 N/A physical interaction ComPPI
PNP GLO1 25348397 N/A physical interaction ComPPI
PNP ITGA4 25348397 N/A physical interaction ComPPI
PNP HECW2 25348397 N/A physical interaction ComPPI
PNP GMPS 25348397 N/A physical interaction ComPPI
PNP MTAP 25348397 N/A physical interaction ComPPI
PNP ENO2 25348397 N/A physical interaction ComPPI
PNP PPME1 25348397 N/A physical interaction ComPPI
PNP SBDS 25348397 N/A physical interaction ComPPI
PNP PSMD5 25348397 N/A physical interaction ComPPI
PNP RAB1A 25348397 N/A physical interaction ComPPI
PNP ENO1 25348397 N/A physical interaction ComPPI
PNP MOV10 25348397 N/A physical interaction ComPPI
PNP NXF1 25348397 N/A physical interaction ComPPI
PNP ABCE1 25348397 N/A physical interaction ComPPI
PNP HNRNPA1 25348397 N/A physical interaction ComPPI
PNP ECHDC1 25348397 N/A physical interaction ComPPI
PNP MCM2 25348397 N/A physical interaction ComPPI
PNP DERL1 25348397 N/A physical interaction ComPPI
PNP RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PNP MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PNP HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PNP EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PNP IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PNP VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
PNP KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PNP CNTFR 15051883 27898060 N/A N/A OmniPath

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