Gene Information gene info

GENE:PRSS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRSS1
FullNmae serine protease 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9475
EnsembleID ENSG00000204983
Uniprot P07477

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRSS1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRSS1 GO:0004252,GO:0004252,GO:0005576,GO:0005576,GO:0005615,GO:0006508,GO:0007586,GO:0022617,GO:0046872,GO:0062023,GO:0072562

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRSS1 hsa:5644 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
PRSS1 hsa:5644 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
PRSS1 hsa:5644 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)
PRSS1 hsa:5644 path:hsa05164 Influenza A - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PRSS1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PRSS1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PRSS1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 PRSS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PRSS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PRSS1 SLPI 25361965 interaction type N/A PTMCode2
SLPI PRSS1 25361965 interaction type N/A PTMCode2
PRSS1 MMP9 25361965 interaction type N/A PTMCode2
MMP9 PRSS1 25361965 interaction type N/A PTMCode2
APP PRSS1 25361965 interaction type N/A PTMCode2
PRSS1 APP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC73 PRSS1 25348397 N/A physical interaction ComPPI
KRT2 PRSS1 25348397 N/A physical interaction ComPPI
GRB2 PRSS1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SERPINF2 PRSS1 14525934 2437112 25348397 27898060 9169621 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
SERPINB13 PRSS1 10512713 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SERPINA1 PRSS1 11057674 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN4 PRSS1 14525934 25348397 27898060 8910369 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SERPINB8 PRSS1 14525934 25348397 9402754 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DDX5 PRSS1 25348397 N/A physical interaction ComPPI
STK38 PRSS1 25348397 N/A physical interaction ComPPI
PRSS1 TST 14525934 25348397 27898060 8340386 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PRSS1 SPINK5 10419450 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRSS1 DEFA5 12021776 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PRSS1 ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRSS1 LGR4 25348397 N/A physical interaction ComPPI
PRSS1 CEP250 25348397 N/A physical interaction ComPPI
PRSS1 STK38L 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRSS1 KRT1 25348397 N/A physical interaction ComPPI
PRSS1 KRT10 25348397 N/A physical interaction ComPPI
PRSS1 SNCA 25348397 N/A physical interaction ComPPI
PRSS1 HUWE1 25348397 N/A physical interaction ComPPI
PRSS1 VPS18 25348397 N/A physical interaction ComPPI
PRSS1 FOXA1 25348397 N/A physical interaction ComPPI
PRSS1 PPP2R2B 19156129 24234451 25348397 association pull down ComPPI,IntAct
PRSS1 NFKB1 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
WTAP PRSS1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
PRKCA PRSS1 27898060 8683601 N/A N/A OmniPath
PRSS1 F2RL1 27898060 9349532 stimulant N/A OmniPath

Visualization