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GENE：PSMB7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMB7
FullNmae proteasome 20S subunit beta 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9544
EnsembleID ENSG00000136930
Uniprot Q99436

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMB7 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMB7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMB7 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMB7 GO:0000502,GO:0000502,GO:0004175,GO:0004298,GO:0005515,GO:0005576,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005839,GO:0005839,GO:0010498,GO:0016604,GO:0019774,GO:0019774,GO:0034774,GO:0043161,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMB7 hsa:5695 path:hsa03050 Proteasome - Homo sapiens (human)
PSMB7 hsa:5695 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMB7 hsa:5695 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMB7 hsa:5695 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMB7 hsa:5695 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMB7 hsa:5695 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMB7 hsa:5695 path:hsa05020 Prion disease - Homo sapiens (human)
PSMB7 hsa:5695 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PSMB7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSMB7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PSMB7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PSMB7 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PSMB7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PSMB7 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PSMB7 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 PSMB7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E PSMB7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000048D44E PSMB7 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PSMA4 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMA4 25361965 interaction type N/A PTMCode2
PSMB7 PSMC1 25361965 interaction type N/A PTMCode2
PSMC1 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMD11 25361965 interaction type N/A PTMCode2
PSMD11 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMA5 25361965 interaction type N/A PTMCode2
PSMA5 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMA1 25361965 interaction type N/A PTMCode2
PSMA1 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMB10 25361965 interaction type N/A PTMCode2
PSMB10 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB7 25361965 interaction type N/A PTMCode2
PSMD7 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMD7 25361965 interaction type N/A PTMCode2
PSMA3 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMA3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CBX8 PSMB7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF1B PSMB7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB10 PSMB7 20723761 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PSMB7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMC3 PSMB7 25348397 N/A physical interaction ComPPI
PSMC6 PSMB7 25348397 N/A physical interaction ComPPI
KIF5B PSMB7 25348397 N/A physical interaction ComPPI
PSMD14 PSMB7 25348397 N/A physical interaction ComPPI
PSMD7 PSMB7 25348397 N/A physical interaction ComPPI
SKP1 PSMB7 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
UBE2D1 PSMB7 25348397 N/A physical interaction ComPPI
PSMB2 PSMB7 20723761 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA3 PSMB7 25348397 N/A physical interaction ComPPI
PSMD11 PSMB7 25348397 N/A physical interaction ComPPI
UBC PSMB7 25348397 N/A physical interaction ComPPI
PLK1 PSMB7 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PSMA1 PSMB7 12376572 24234451 25348397 25599644 29568061 association,physical association affinity chromatography technology,pull down,x-ray crystallography,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PSMA6 PSMB7 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA5 PSMB7 25348397 N/A physical interaction ComPPI
PSMB9 PSMB7 14733938 20723761 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PSMD8 PSMB7 25348397 N/A physical interaction ComPPI
PSMB8 PSMB7 20723761 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD1 PSMB7 20723761 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SYVN1 PSMB7 25348397 N/A physical interaction ComPPI
PSMC5 PSMB7 25348397 N/A physical interaction ComPPI
HUWE1 PSMB7 25348397 N/A physical interaction ComPPI
RAD23A PSMB7 25348397 N/A physical interaction ComPPI
EPB41L1 PSMB7 25348397 N/A physical interaction ComPPI
HTT PSMB7 23275563 24234451 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
PSMC4 PSMB7 25348397 N/A physical interaction ComPPI
NOS2 PSMB7 25348397 N/A physical interaction ComPPI
AURKA PSMB7 25348397 N/A physical interaction ComPPI
PSMD2 PSMB7 25348397 N/A physical interaction ComPPI
SERPINA10 PSMB7 25348397 N/A physical interaction ComPPI
RAD23B PSMB7 25348397 N/A physical interaction ComPPI
PRKN PSMB7 25348397 N/A physical interaction ComPPI
PSMD4 PSMB7 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP8 PSMB7 25348397 N/A physical interaction ComPPI
PCMT1 PSMB7 25348397 N/A physical interaction ComPPI
PSMB5 PSMB7 14525934 14733938 17948026 20723761 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TRIM25 PSMB7 25348397 N/A physical interaction ComPPI
CAST PSMB7 25348397 N/A physical interaction ComPPI
PSME1 PSMB7 25348397 N/A physical interaction ComPPI
PSME2 PSMB7 25348397 N/A physical interaction ComPPI
PSMC1 PSMB7 25348397 N/A physical interaction ComPPI
AMFR PSMB7 25348397 N/A physical interaction ComPPI
DERL1 PSMB7 25348397 N/A physical interaction ComPPI
CLIC4 PSMB7 25348397 N/A physical interaction ComPPI
FBXO7 PSMB7 25348397 N/A physical interaction ComPPI
PSMB4 PSMB7 17948026 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HECW2 PSMB7 25348397 N/A physical interaction ComPPI
PSMB1 PSMB7 14525934 14733938 17948026 20723761 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB3 PSMB7 14525934 14733938 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB7 EMG1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PSMB7 POMP 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB7 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 PCK1 25348397 N/A physical interaction ComPPI
PSMB7 PSMB6 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB7 PSMA4 20723761 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 PSMA8 25348397 N/A physical interaction ComPPI
PSMB7 PSMA7 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
PSMB7 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 PSMC2 25348397 N/A physical interaction ComPPI
PSMB7 PSMD13 25348397 N/A physical interaction ComPPI
PSMB7 PSMD3 25348397 N/A physical interaction ComPPI
PSMB7 PSMD12 25348397 N/A physical interaction ComPPI
PSMB7 SYAP1 25348397 N/A physical interaction ComPPI
PSMB7 SMAP 25348397 N/A physical interaction ComPPI
PSMB7 S100A9 25348397 N/A physical interaction ComPPI
PSMB7 NUDCD2 25348397 N/A physical interaction ComPPI
PSMB7 TMOD3 25348397 N/A physical interaction ComPPI
PSMB7 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 AFP 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMB7 FUS 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMB7 ACACA 25348397 N/A physical interaction ComPPI
PSMB7 PSMG2 25348397 N/A physical interaction ComPPI
PSMB7 PSME4 25348397 N/A physical interaction ComPPI
PSMB7 NAA25 25348397 N/A physical interaction ComPPI
PSMB7 PSMG1 25348397 N/A physical interaction ComPPI
PSMB7 PSMG3 25348397 N/A physical interaction ComPPI
PSMB7 POLR1C 25348397 N/A physical interaction ComPPI
PSMB7 PSMD5 25348397 N/A physical interaction ComPPI
PSMB7 PYGL 25348397 N/A physical interaction ComPPI
PSMB7 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB7 L3MBTL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
ADRM1 PSMB7 25348397 N/A physical interaction ComPPI
PSMF1 PSMB7 25348397 N/A physical interaction ComPPI
PSMB7 PSMB7 14525934 14733938 17948026 24234451 physical association two hybrid,two hybrid HPRD,IntAct

Visualization










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