GENE:RAB18
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RAB18 |
| FullNmae | RAB18, member RAS oncogene family |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14244 |
| EnsembleID | ENSG00000099246 |
| Uniprot | Q9NP72 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RAB18 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RAB18 | GO:0001654,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005789,GO:0005794,GO:0005811,GO:0005829,GO:0005886,GO:0006886,GO:0007264,GO:0007420,GO:0012505,GO:0016324,GO:0019003,GO:0030667,GO:0034389,GO:0034389,GO:0071782,GO:0071786 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | RAB18 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | RAB18 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | RAB18 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | RAB18 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RAB18 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RAB18 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | RAB18 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000005481D | RAB18 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002152A8 | RAB18 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000016D2D4 | RAB18 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000012A1DD | RAB18 | 24477653 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00002E628F | RAB18 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | RAB18 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | RAB18 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | RAB18 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | RAB18 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023133F | RAB18 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | RAB18 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001AFC71 | RAB18 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000028BB8 | RAB18 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001EB3 | RAB18 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | RAB18 | 25416803 27451075 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PDE6D | RAB18 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PPP2R1A | RAB18 | 14525934 17540176 24234451 25348397 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction | ComPPI,HPRD,IntAct |
| ERRFI1 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| SLAMF1 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| RAB8A | RAB18 | 24234451 25348397 26824392 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| TOM1L1 | RAB18 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| CFTR | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| TNF | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| CHM | RAB18 | 12535645 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| GDI1 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| ADRB2 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| EGFR | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| CENPJ | RAB18 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| TAX1BP1 | RAB18 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| LAMP2 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R1B | RAB18 | 14525934 17540176 24234451 25348397 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| TGOLN2 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| CNTROB | RAB18 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| PTGER3 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| RAB2B | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| ICAM2 | RAB18 | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | SRPRB | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | HSD11B1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | VSIG4 | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | ARL13B | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | HEPACAM2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | AGK | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | FAM107A | 25348397 | N/A | physical interaction | ComPPI |
| RAB18 | AQP6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RAB18 | ELOVL4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MKI67 | RAB18 | 24234451 26949251 | association | anti tag coimmunoprecipitation | IntAct |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B9A3E | RAB18 | 27087310 | direct interaction,inhibition | N/A | NPInter |
