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GENE：ROBO3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ROBO3
FullNmae roundabout guidance receptor 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13433
EnsembleID ENSG00000154134
Uniprot Q96MS0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ROBO3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ROBO3 GO:0005515,GO:0005886,GO:0005886,GO:0007156,GO:0007411,GO:0007411,GO:0007411,GO:0016020,GO:0016199,GO:0030424,GO:0070593,GO:0098632,GO:1902669

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ROBO3 hsa:64221 path:hsa04360 Axon guidance - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ROBO3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ROBO3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ROBO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ROBO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ROBO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ROBO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ROBO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ROBO3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PRKCA ROBO3 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
APOA1 ROBO3 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NEDD4L ROBO3 25348397 N/A physical interaction ComPPI
RBMX ROBO3 25348397 N/A physical interaction ComPPI
NELL2 ROBO3 25348397 26586761 27898060 N/A physical interaction,solid phase assay,surface plasmon resonance array ComPPI,OmniPath
LNX1 ROBO3 25348397 N/A physical interaction ComPPI
MTUS2 ROBO3 25348397 N/A physical interaction ComPPI
APP ROBO3 25348397 N/A physical interaction ComPPI
ROBO3 CCDC57 25348397 N/A physical interaction ComPPI
PRKCA ROBO3 25882844 27898060 N/A N/A OmniPath
ROBO1 ROBO3 16226035 27898060 N/A N/A OmniPath
NCAM1 ROBO3 16226035 27898060 stimulant N/A OmniPath

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