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GENE：RORC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RORC
FullNmae RAR related orphan receptor C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10260
EnsembleID ENSG00000143365
Uniprot P51449

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RORC immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RORC GO:0000122,GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0001227,GO:0003700,GO:0004879,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0006357,GO:0006805,GO:0008142,GO:0008142,GO:0008270,GO:0010906,GO:0016604,GO:0019218,GO:0030522,GO:0032922,GO:0036315,GO:0042753,GO:0045598,GO:0045893,GO:0060612,GO:0072539,GO:0098531,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RORC hsa:6097 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
RORC hsa:6097 path:hsa04710 Circadian rhythm - Homo sapiens (human)
RORC hsa:6097 path:hsa05321 Inflammatory bowel disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RXRA RORC 23180781 24670648 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR RORC 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RORC 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 RORC 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RORC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RORC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RORC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RORC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RORC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 RORC 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002152A8 RORC 23359619 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002152A8 RORC 23359619 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000237AF9 RORC 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000521626 RORC 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 RORC 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
BHLHE40 RORC 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
PPP1CC RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2R1A RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP1CB RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SRC RORC 25348397 N/A physical interaction ComPPI
JUN RORC 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CREBBP RORC 20203100 24234451 25348397 N/A amplified luminescent proximity homogeneous assay ComPPI,IntAct
NCOA1 RORC 20203100 24234451 25348397 N/A amplified luminescent proximity homogeneous assay ComPPI,IntAct
EP300 RORC 25348397 N/A physical interaction ComPPI
PPARGC1A RORC 20203100 24234451 25348397 N/A amplified luminescent proximity homogeneous assay ComPPI,IntAct
NCOA6 RORC 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CSNK1E RORC 25348397 N/A physical interaction ComPPI
PPP1CA RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF4EBP1 RORC 10405182 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DDX5 RORC 24234451 25348397 26675721 physical association pull down,physical interaction ComPPI,IntAct
PPP2CA RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2R5E RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
USP4 RORC 25348397 N/A physical interaction ComPPI
PSMC5 RORC 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRAF5 RORC 25348397 N/A physical interaction ComPPI
CTSA RORC 25348397 N/A physical interaction ComPPI
GLB1 RORC 25348397 N/A physical interaction ComPPI
ARNTL RORC 25348397 N/A physical interaction ComPPI
PER2 RORC 25348397 N/A physical interaction ComPPI
PPP2R1B RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CLOCK RORC 25348397 N/A physical interaction ComPPI
ARNTL2 RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2R5D RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RORB RORC 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SCGB1D2 RORC 25348397 N/A physical interaction ComPPI
FOXP3 RORC 18368049 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RORC EVI2A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RORC DELEC1 25348397 N/A physical interaction ComPPI
RORC BHLHE41 25348397 N/A physical interaction ComPPI
RORC NPAS2 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RORC NR1D2 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RORC FBXL15 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RORC HDAC1 25348397 N/A physical interaction ComPPI
RORC USP15 25348397 N/A physical interaction ComPPI
RORC ANKHD1 25348397 N/A physical interaction ComPPI
RORC TP53 25348397 N/A physical interaction ComPPI
CIPC RORC 25348397 N/A physical interaction ComPPI
RORC CHD4 15144897 27898060 N/A N/A OmniPath
RORC ARNTL 18454201 23555304 27898060 stimulant N/A OmniPath
RORC EIF4EBP1 10405182 11777913 18669648 19413330 20068231 27898060 inhibition N/A OmniPath

Visualization










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