GENE：RRAD
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RRAD |
| FullNmae | RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10446 |
| EnsembleID | ENSG00000166592 |
| Uniprot | P55042 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RRAD | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| RRAD | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RRAD | GO:0003924,GO:0005246,GO:0005515,GO:0005516,GO:0005525,GO:0005829,GO:0005886,GO:0007264 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | RRAD | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | RRAD | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP73 | RRAD | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | RRAD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RRAD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RRAD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RRAD | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | RRAD | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001919B0 | RRAD | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E728C | RRAD | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005E58C | RRAD | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003ACE11 | RRAD | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F0C23 | RRAD | 23592263 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005C1F22 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F4AC3 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5BAA | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AA464 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122ED0 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032EF64 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237CBD | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000B1C9 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A07C1 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000324096 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CC005 | RRAD | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C1E1 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A8BC6 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032AE90 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5ECC | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048F59D | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004CCDA3 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000451A1 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D12AC | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CE28 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | RRAD | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CAMK2A | RRAD | 22135298 | phosphorylation | N/A | PhosphoSite |
| CSNK2A1 | RRAD | 22135298 | phosphorylation | N/A | PhosphoSite |
| PRKACA | RRAD | 22135298 | phosphorylation | N/A | PhosphoSite |
| PRKCA | RRAD | 22135298 | phosphorylation | N/A | PhosphoSite |
| RRAD | CAMK2B | 25361965 | interaction type | N/A | PTMCode2 |
| CAMK2B | RRAD | 25361965 | interaction type | N/A | PTMCode2 |
| RRAD | TPM2 | 25361965 | interaction type | N/A | PTMCode2 |
| TPM2 | RRAD | 25361965 | interaction type | N/A | PTMCode2 |
| NME1 | RRAD | 25361965 | interaction type | N/A | PTMCode2 |
| RRAD | NME1 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CALM1 | RRAD | 25348397 | N/A | physical interaction | ComPPI |
| MMP14 | RRAD | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| PRKCA | RRAD | 14525934 25348397 7876254 9677319 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| TPM2 | RRAD | 14525934 25348397 27898060 8557685 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| PRKACA | RRAD | 14525934 25348397 7876254 9677319 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CCNDBP1 | RRAD | 20460530 24234451 25348397 27898060 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,pull down,confocal microscopy | ComPPI,IntAct,OmniPath |
| YWHAZ | RRAD | 10441394 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| PRKCB | RRAD | 14525934 25348397 7876254 9677319 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CSNK2A1 | RRAD | 14525934 25348397 7876254 9677319 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| NME1 | RRAD | 10611312 11280768 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| RRAD | CAMK2G | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| RRAD | CSNK2B | 25348397 | N/A | physical interaction | ComPPI |
| RRAD | EGFR | 25348397 | N/A | physical interaction | ComPPI |
| RRAD | STAT3 | 25348397 | N/A | physical interaction | ComPPI |
| RRAD | EEA1 | 25348397 | N/A | physical interaction | ComPPI |
| RRAD | CCDC141 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| RRAD | CALM2 | 14525934 9115241 | N/A | experimental interaction detection | HPRD |
| PRKCA | RRAD | 27898060 7876254 9677319 | N/A | N/A | OmniPath |
| PRKCZ | RRAD | 27898060 9677319 | N/A | N/A | OmniPath |