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GENE：S100A4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol S100A4
FullNmae S100 calcium binding protein A4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10494
EnsembleID ENSG00000196154
Uniprot P26447

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
S100A4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
S100A4 GO:0001837,GO:0003723,GO:0003779,GO:0005509,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005615,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0042056,GO:0042802,GO:0043123,GO:0043123,GO:0046914,GO:0048306,GO:0048471,GO:0048471,GO:0050786,GO:0050786,GO:0050918,GO:0062023,GO:0070062

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMAD3 S100A4 20070253 23180781 physical association anti tag coimmunoprecipitation,pull down,surface plasmon resonance InnateDB
SMAD2 S100A4 20070253 23180781 physical association pull down InnateDB
IL7R S100A4 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFAT5 S100A4 21289293 23180781 physical association anti tag coimmunoprecipitation InnateDB
LY96 S100A4 23180781 23667563 physical association affinity technology InnateDB
S100A4 AGER 23180781 23667563 physical association affinity technology InnateDB
AGER S100A4 23180781 23667563 physical association affinity technology InnateDB

Source Target Pmid Interactiontype Methods Database
HIF1A S100A4 19637235 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 S100A4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NFAT5 S100A4 21289293 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 S100A4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 S100A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 S100A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 S100A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR S100A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CIITA S100A4 17143014 trascriptional regulation,stimulation inferred by curator TFlink
CREBBP S100A4 17143014 trascriptional regulation,stimulation inferred by curator TFlink
EP300 S100A4 17143014 trascriptional regulation,stimulation inferred by curator TFlink
PTTG1 S100A4 19351864 trascriptional regulation,stimulation inferred by curator TFlink
STAT4 S100A4 22740693 trascriptional regulation,stimulation inferred by curator TFlink
TP53 S100A4 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EB9FC S100A4 25416803 27544906 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
METAP2 S100A4 25361965 interaction type N/A PTMCode2
S100A4 METAP2 25361965 interaction type N/A PTMCode2
ANXA2 S100A4 25361965 interaction type N/A PTMCode2
S100A4 ANXA2 25361965 interaction type N/A PTMCode2
TP53 S100A4 25361965 interaction type N/A PTMCode2
S100A4 TP53 25361965 interaction type N/A PTMCode2
S100A4 S100A4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DYNLL1 S100A4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100B S100A4 21516116 24234451 25348397 25416956 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
S100P S100A4 14525934 15171681 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
S100A4 CCN3 12147716 14525934 14606958 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
S100A4 S100A1 10753920 10869553 14525934 15608682 16189514 24234451 25348397 27898060 9926943 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct,OmniPath
S100A4 TPM3 14525934 25348397 8120097 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A4 SEPTIN2 14525934 14531065 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A4 METAP2 11994292 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
S100A4 PPFIBP1 11836260 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
S100A4 SEPTIN7 14525934 14531065 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A4 SEPTIN6 14525934 14531065 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A4 MYH4 14525934 14640694 25348397 9405067 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
S100A4 TPM2 14525934 25348397 8120097 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A4 ACTA1 14525934 14640694 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A4 BAG6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
S100A4 UNC119 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
S100A4 ANXA2 14525934 15788416 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
S100A4 MYH2 12756252 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
S100A4 MYH9 14525934 15289939 20421509 22483112 24234451 25348397 27898060 9405067 physical association anti bait coimmunoprecipitation,classical fluorescence spectroscopy,transmission electron microscopy,cosedimentation in solution,experimental interaction detection,isothermal titration calorimetry,light scattering,molecular sieving,nuclear magnetic resonance,surface plasmon resonance,physical interaction,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct,OmniPath
S100A4 MYH10 25348397 N/A in vitro ComPPI
S100A4 TP53 11278647 11527429 12942774 14525934 15116098 19740107 20591429 23752197 24234451 25348397 colocalization,physical association cross-linking study,experimental interaction detection,far western blotting,fluorescence polarization spectroscopy,molecular sieving,physical interaction,confocal microscopy,proximity ligation assay ComPPI,HPRD,IntAct
S100A4 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 MDM2 20591429 24234451 25348397 physical association molecular sieving,surface plasmon resonance,physical interaction,competition binding ComPPI,IntAct
S100A4 SMAD3 25348397 N/A physical interaction ComPPI
S100A4 SMAD2 25348397 N/A physical interaction ComPPI
S100A4 IGBP1 25348397 N/A physical interaction ComPPI
S100A4 TOM1L2 25348397 N/A physical interaction ComPPI
S100A4 UNK 25348397 N/A physical interaction ComPPI
S100A4 SUGT1 25348397 N/A physical interaction ComPPI
S100A4 PSMA1 25348397 N/A physical interaction ComPPI
S100A4 SELENBP1 25348397 N/A physical interaction ComPPI
S100A4 SNRPF 25348397 N/A physical interaction ComPPI
S100A4 TRIP13 25348397 N/A physical interaction ComPPI
S100A4 ZZEF1 25348397 N/A physical interaction ComPPI
S100A4 CEP76 25348397 N/A physical interaction ComPPI
S100A4 MOV10 25348397 N/A physical interaction ComPPI
S100A4 NXF1 25348397 N/A physical interaction ComPPI
S100A4 EGFR 24234451 24658140 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
S100A4 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
S100A4 SRPK2 25348397 N/A physical interaction ComPPI
S100A4 XIAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 NPAT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 CDK2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 NR2C2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 PHF12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 S100A6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 SUV39H1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 DNAJA3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 DNAJB6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 POP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 CNTRL 25348397 N/A physical interaction ComPPI
S100A4 KAT7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 WDFY3 25348397 N/A physical interaction ComPPI
S100A4 SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 BRD1 25348397 N/A physical interaction ComPPI
S100A4 UQCR10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 BBX 25348397 N/A physical interaction ComPPI
S100A4 CORO7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 PTGR2 25348397 N/A physical interaction ComPPI
S100A4 ESCO2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 RHOU 25348397 N/A physical interaction ComPPI
S100A4 RHOA 25348397 N/A physical interaction ComPPI
S100A4 AREG 19740107 24234451 25348397 N/A far western blotting,pull down ComPPI,IntAct
S100A4 HBEGF 19740107 24234451 25348397 N/A far western blotting ComPPI,IntAct
S100A4 EGF 19740107 24234451 25348397 N/A far western blotting ComPPI,IntAct
S100A4 BTC 19740107 24234451 25348397 N/A far western blotting,pull down ComPPI,IntAct
S100A4 IGHG3 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
S100A4 S100A4 11278510 11994292 12756252 14525934 20421509 22483112 24234451 N/A transmission electron microscopy,cosedimentation in solution,cross-linking study,experimental interaction detection,light scattering,molecular sieving,x-ray crystallography,two hybrid HPRD,IntAct
MATR3 S100A4 24234451 30021884 physical association cross-linking study IntAct
IL7R S100A4 20167604 27898060 N/A N/A OmniPath

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