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GENE：S100A6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol S100A6
FullNmae S100 calcium binding protein A6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10496
EnsembleID ENSG00000197956
Uniprot P06703

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
S100A6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
S100A6 GO:0001726,GO:0005509,GO:0005509,GO:0005509,GO:0005515,GO:0005523,GO:0005576,GO:0005634,GO:0005634,GO:0005635,GO:0005635,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0007165,GO:0007409,GO:0008270,GO:0009898,GO:0015075,GO:0034220,GO:0042803,GO:0042803,GO:0044548,GO:0044548,GO:0048146,GO:0048306,GO:0048306,GO:0048471,GO:0048471,GO:0062023,GO:0070062

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 S100A6 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA2 S100A6 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 S100A6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
USF1 S100A6 11118618 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
FOXP3 S100A6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 S100A6 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 S100A6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 S100A6 12859951 trascriptional regulation,stimulation inferred by curator TFlink
NFKBIA S100A6 12859951 trascriptional regulation,stimulation inferred by curator TFlink
RELA S100A6 12859951 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003E1A9 S100A6 25241899 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection,clip TarBase

Source Target Pmid Interactiontype Methods Database
S100B S100A6 25361965 interaction type N/A PTMCode2
S100A6 S100B 25361965 interaction type N/A PTMCode2
ANXA2 S100A6 25361965 interaction type N/A PTMCode2
S100A6 ANXA2 25361965 interaction type N/A PTMCode2
S100A6 SUGT1 25361965 interaction type N/A PTMCode2
SUGT1 S100A6 25361965 interaction type N/A PTMCode2
FKBP4 S100A6 25361965 interaction type N/A PTMCode2
S100A6 FKBP4 25361965 interaction type N/A PTMCode2
TP53 S100A6 25361965 interaction type N/A PTMCode2
S100A6 TP53 25361965 interaction type N/A PTMCode2
ANXA11 S100A6 25361965 interaction type N/A PTMCode2
S100A6 ANXA11 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KPNA2 S100A6 20965181 24234451 25348397 physical association pull down,electrophoretic mobility supershift assay ComPPI,IntAct
CD2BP2 S100A6 25348397 N/A physical interaction ComPPI
S100B S100A6 10913138 14525934 24234451 25348397 29997244 9925766 colocalization,physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid,experimental interaction detection,physical interaction,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
S100A4 S100A6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 S100A6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
S100A6 GAPDH 14525934 1999197 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A6 ANXA2 14525934 1999197 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A6 ANXA11 10037139 12601007 1299619 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
S100A6 CACYBP 12042313 14525934 18803400 22295074 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
S100A6 SUGT1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
S100A6 MDM2 20591429 24234451 25348397 N/A molecular sieving,surface plasmon resonance,physical interaction ComPPI,IntAct
S100A6 CDK2 25348397 N/A physical interaction ComPPI
S100A6 DHX36 25348397 N/A physical interaction ComPPI
S100A6 CLNS1A 25348397 N/A physical interaction ComPPI
S100A6 SEC24A 25348397 N/A physical interaction ComPPI
S100A6 NUP214 25348397 N/A physical interaction ComPPI
S100A6 TOM1L2 25348397 N/A physical interaction ComPPI
S100A6 SEC23A 25348397 N/A physical interaction ComPPI
S100A6 STUB1 25348397 N/A physical interaction ComPPI
S100A6 FKBP4 20188096 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,competition binding ComPPI,IntAct
S100A6 PEX5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
S100A6 TP53 20591429 24234451 25348397 N/A molecular sieving,physical interaction ComPPI,IntAct
S100A6 HEBP1 25348397 N/A physical interaction ComPPI
S100A6 YEATS4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A6 TM9SF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A6 U2AF2 25348397 N/A physical interaction ComPPI
S100A6 CHCHD7 25348397 N/A physical interaction ComPPI
S100A6 MANBAL 25348397 N/A physical interaction ComPPI
S100A6 TBC1D2B 25348397 N/A physical interaction ComPPI
S100A6 UFM1 25348397 N/A physical interaction ComPPI
S100A6 TRIM25 25348397 N/A physical interaction ComPPI
S100A6 CCND2 25348397 N/A physical interaction ComPPI
S100A6 GRB2 12577067 24234451 25348397 association pull down ComPPI,IntAct
S100A6 YWHAZ 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
S100A6 FAM25C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
S100A6 CANX 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PPID S100A6 25348397 N/A physical interaction ComPPI
S100A6 S100A6 10913138 11937060 14525934 24234451 physical association two hybrid,experimental interaction detection HPRD,IntAct

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