GENE:SELP
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SELP |
FullNmae | selectin P |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:10721 |
EnsembleID | ENSG00000174175 |
Uniprot | P16109 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SELP | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SELP | GO:0001530,GO:0002687,GO:0005509,GO:0005515,GO:0005615,GO:0005615,GO:0005886,GO:0005886,GO:0006954,GO:0007155,GO:0007157,GO:0007159,GO:0008201,GO:0009897,GO:0009897,GO:0010572,GO:0016339,GO:0031088,GO:0031092,GO:0031092,GO:0032496,GO:0033623,GO:0033691,GO:0033691,GO:0034097,GO:0035584,GO:0042806,GO:0043208,GO:0048306,GO:0050829,GO:0050901,GO:0050901,GO:0051897,GO:0070492,GO:0070492,GO:1903238 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
SELP | hsa:6403 | path:hsa04514 | Cell adhesion molecules - Homo sapiens (human) |
SELP | hsa:6403 | path:hsa04613 | Neutrophil extracellular trap formation - Homo sapiens (human) |
SELP | hsa:6403 | path:hsa05144 | Malaria - Homo sapiens (human) |
SELP | hsa:6403 | path:hsa05150 | Staphylococcus aureus infection - Homo sapiens (human) |
SELP | hsa:6403 | path:hsa05171 | Coronavirus disease - COVID-19 - Homo sapiens (human) |
SELP | hsa:6403 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PTX3 | SELP | 20208538 23180781 | physical association | surface plasmon resonance,solid phase assay | InnateDB |
GP1BA | SELP | 10499919 23180781 | physical association | solid phase assay | InnateDB |
SELPLG | SELP | 11081633 23180781 | physical association | solid phase assay | InnateDB |
SERPING1 | SELP | 14568956 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SNX17 | SELP | 11237770 23180781 | physical association | two hybrid | InnateDB |
VCAN | SELP | 10950950 23180781 | physical association | solid phase assay | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
FOXP3 | SELP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ETS1 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
NFKB2 | SELP | 7559449 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT6 | SELP | 10364072 | trascriptional regulation,stimulation | inferred by curator | TFlink |
BCL3 | SELP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SELP | SERPING1 | 25361965 | interaction type | N/A | PTMCode2 |
SERPING1 | SELP | 25361965 | interaction type | N/A | PTMCode2 |
SELP | GP1BA | 25361965 | interaction type | N/A | PTMCode2 |
GP1BA | SELP | 25361965 | interaction type | N/A | PTMCode2 |
SNX17 | SELP | 25361965 | interaction type | N/A | PTMCode2 |
SELP | SNX17 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CD24 | SELP | 14525934 25348397 9129046 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SERPING1 | SELP | 14525934 14568956 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SELP | SELPLG | 10713099 11081633 14525934 17064811 19118202 24234451 25348397 26627825 9128259 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,surface plasmon resonance array | ComPPI,HPRD,IntAct |
SELP | AP1M1 | 11247301 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
SELP | SNX17 | 11237770 14525934 23382219 25348397 27898060 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,OmniPath |
SELP | EZR | 10733515 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SELP | FUT4 | 14525934 25348397 27898060 7508745 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
SELP | VCAN | 10950950 14525934 25348397 | N/A | experimental interaction detection,physical interaction,solid phase assay | ComPPI,HPRD |
SELP | COL18A1 | 25348397 | N/A | solid phase assay | ComPPI |
SELP | GP1BA | 10499919 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
SELP | SNX27 | 25348397 | N/A | physical interaction | ComPPI |
SELP | SELP | 11081633 14525934 | N/A | experimental interaction detection | HPRD |
SELP | NUMB | 19138666 27898060 | N/A | N/A | OmniPath |
SELP | PTX3 | 20208538 27898060 | N/A | N/A | OmniPath |
MAP4K2 | SELP | 27898060 7691235 | N/A | N/A | OmniPath |
SELPLG | SELP | 10713099 11081633 17064811 19118202 23994464 26627825 27898060 9128259 9129046 | stimulant | N/A | OmniPath |