GENE:SELP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SELP |
| FullNmae | selectin P |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10721 |
| EnsembleID | ENSG00000174175 |
| Uniprot | P16109 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SELP | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SELP | GO:0001530,GO:0002687,GO:0005509,GO:0005515,GO:0005615,GO:0005615,GO:0005886,GO:0005886,GO:0006954,GO:0007155,GO:0007157,GO:0007159,GO:0008201,GO:0009897,GO:0009897,GO:0010572,GO:0016339,GO:0031088,GO:0031092,GO:0031092,GO:0032496,GO:0033623,GO:0033691,GO:0033691,GO:0034097,GO:0035584,GO:0042806,GO:0043208,GO:0048306,GO:0050829,GO:0050901,GO:0050901,GO:0051897,GO:0070492,GO:0070492,GO:1903238 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SELP | hsa:6403 | path:hsa04514 | Cell adhesion molecules - Homo sapiens (human) |
| SELP | hsa:6403 | path:hsa04613 | Neutrophil extracellular trap formation - Homo sapiens (human) |
| SELP | hsa:6403 | path:hsa05144 | Malaria - Homo sapiens (human) |
| SELP | hsa:6403 | path:hsa05150 | Staphylococcus aureus infection - Homo sapiens (human) |
| SELP | hsa:6403 | path:hsa05171 | Coronavirus disease - COVID-19 - Homo sapiens (human) |
| SELP | hsa:6403 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PTX3 | SELP | 20208538 23180781 | physical association | surface plasmon resonance,solid phase assay | InnateDB |
| GP1BA | SELP | 10499919 23180781 | physical association | solid phase assay | InnateDB |
| SELPLG | SELP | 11081633 23180781 | physical association | solid phase assay | InnateDB |
| SERPING1 | SELP | 14568956 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| SNX17 | SELP | 11237770 23180781 | physical association | two hybrid | InnateDB |
| VCAN | SELP | 10950950 23180781 | physical association | solid phase assay | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FOXP3 | SELP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | SELP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFKB2 | SELP | 7559449 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT6 | SELP | 10364072 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| BCL3 | SELP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SELP | SERPING1 | 25361965 | interaction type | N/A | PTMCode2 |
| SERPING1 | SELP | 25361965 | interaction type | N/A | PTMCode2 |
| SELP | GP1BA | 25361965 | interaction type | N/A | PTMCode2 |
| GP1BA | SELP | 25361965 | interaction type | N/A | PTMCode2 |
| SNX17 | SELP | 25361965 | interaction type | N/A | PTMCode2 |
| SELP | SNX17 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CD24 | SELP | 14525934 25348397 9129046 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| SERPING1 | SELP | 14525934 14568956 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| SELP | SELPLG | 10713099 11081633 14525934 17064811 19118202 24234451 25348397 26627825 9128259 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,surface plasmon resonance array | ComPPI,HPRD,IntAct |
| SELP | AP1M1 | 11247301 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| SELP | SNX17 | 11237770 14525934 23382219 25348397 27898060 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,OmniPath |
| SELP | EZR | 10733515 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| SELP | FUT4 | 14525934 25348397 27898060 7508745 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| SELP | VCAN | 10950950 14525934 25348397 | N/A | experimental interaction detection,physical interaction,solid phase assay | ComPPI,HPRD |
| SELP | COL18A1 | 25348397 | N/A | solid phase assay | ComPPI |
| SELP | GP1BA | 10499919 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| SELP | SNX27 | 25348397 | N/A | physical interaction | ComPPI |
| SELP | SELP | 11081633 14525934 | N/A | experimental interaction detection | HPRD |
| SELP | NUMB | 19138666 27898060 | N/A | N/A | OmniPath |
| SELP | PTX3 | 20208538 27898060 | N/A | N/A | OmniPath |
| MAP4K2 | SELP | 27898060 7691235 | N/A | N/A | OmniPath |
| SELPLG | SELP | 10713099 11081633 17064811 19118202 23994464 26627825 27898060 9128259 9129046 | stimulant | N/A | OmniPath |
