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GENE：SERPING1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SERPING1
FullNmae serpin family G member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1228
EnsembleID ENSG00000149131
Uniprot P05155

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SERPING1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SERPING1 GO:0001869,GO:0004867,GO:0004867,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005615,GO:0005788,GO:0006958,GO:0007596,GO:0008015,GO:0010951,GO:0031093,GO:0042730,GO:0045087,GO:0062023,GO:0070062,GO:0072562

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SERPING1 hsa:710 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
SERPING1 hsa:710 path:hsa05133 Pertussis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
C1S SERPING1 17488724 23180781 physical association comigration in sds page InnateDB
LGALS9 SERPING1 18263896 23180781 physical association pull down InnateDB
SERPING1 SELP 14568956 23180781 physical association anti tag coimmunoprecipitation InnateDB
SERPING1 SELE 14568956 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
HNF1A SERPING1 12184632 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
SMARCA4 SERPING1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SERPING1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SERPING1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SERPING1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SERPING1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00004CCA62 SERPING1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 SERPING1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 SERPING1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 SERPING1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC SERPING1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F SERPING1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002F3336 SERPING1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 SERPING1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SERPING1 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008B558 SERPING1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED SERPING1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 SERPING1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E SERPING1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 SERPING1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD SERPING1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 SERPING1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SELP SERPING1 25361965 interaction type N/A PTMCode2
SERPING1 SELP 25361965 interaction type N/A PTMCode2
SERPING1 C1R 25361965 interaction type N/A PTMCode2
C1R SERPING1 25361965 interaction type N/A PTMCode2
SERPING1 ALB 25361965 interaction type N/A PTMCode2
ALB SERPING1 25361965 interaction type N/A PTMCode2
SERPING1 C1S 25361965 interaction type N/A PTMCode2
C1S SERPING1 25361965 interaction type N/A PTMCode2
SERPING1 MASP2 25361965 interaction type N/A PTMCode2
MASP2 SERPING1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ELANE SERPING1 14525934 25348397 6980881 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GRN SERPING1 25348397 N/A physical interaction ComPPI
PLG SERPING1 14525934 25348397 27898060 9234243 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
F2 SERPING1 11460008 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
ENO1 SERPING1 25348397 N/A physical interaction ComPPI
PLAT SERPING1 14525934 25348397 27898060 7586269 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
SERPING1 SELP 14525934 14568956 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SERPING1 C1R 14525934 25348397 6282262 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SERPING1 MASP1 10946292 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SERPING1 MASP2 10946292 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SERPING1 C1S 14525934 17488724 25348397 27898060 3756141 6604523 9882449 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
SERPING1 SELE 14525934 14568956 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SERPING1 ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SERPING1 BAG6 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SERPING1 NR4A1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SERPING1 SRPK2 25348397 N/A physical interaction ComPPI
SERPING1 CBWD3 25348397 N/A physical interaction ComPPI
SERPING1 ARFGAP2 25348397 N/A physical interaction ComPPI
SERPING1 CREB3 25348397 N/A two hybrid bait and prey pooling approach ComPPI

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