Gene Information gene info

  1. Home

GENE：SHC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SHC1
FullNmae SHC adaptor protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10840
EnsembleID ENSG00000160691
Uniprot P29353

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SHC1 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SHC1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SHC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SHC1 GO:0001525,GO:0001784,GO:0005068,GO:0005154,GO:0005158,GO:0005159,GO:0005168,GO:0005515,GO:0005543,GO:0005759,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005925,GO:0007173,GO:0007507,GO:0008284,GO:0008286,GO:0008286,GO:0030036,GO:0030971,GO:0035556,GO:0042742,GO:0043066,GO:0043410,GO:0043410,GO:0045892,GO:0045893,GO:0046875,GO:0048009,GO:0048408,GO:0070374,GO:0070435,GO:0071363,GO:0098609

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SHC1 hsa:6464 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
SHC1 hsa:6464 path:hsa01522 Endocrine resistance - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04510 Focal adhesion - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04915 Estrogen signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
SHC1 hsa:6464 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05034 Alcoholism - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05214 Glioma - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05224 Breast cancer - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
SHC1 hsa:6464 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GRB2 SHC1 10022831 10086337 10358164 10567412 10749687 10811803 10849428 10961885 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11782427 11960372 11997181 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15341520 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16436051 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23180781 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26192618 26201938 26552706 7510700 7717978 8551221 8837607 9157999 9199344 9570538 9753319 9763606 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
SHC1 ANGPT1 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 CRK 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 CRKL 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 FLT4 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 KDR 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
SHC1 NCK1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
SHC1 VEGFB 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
VEGFA SHC1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
SHC1 SYK 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615 interaction type N/A ACSN
SHC1 PIK3R1 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 MAP2K4 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 PLCG1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
FLT1 SHC1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
SHC1 CXCL8 10086337 10567412 10811803 10849428 10982827 11283723 11447289 11449354 11777939 12175651 12393695 12640133 15520864 15567848 15574420 16076871 16582911 16887996 17496910 17673906 19223473 19449109 26192618 26552706 8551221 interaction type N/A ACSN
SHC1 FYN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
FGFR1 SHC1 17496910 25467007 26192618 interaction type N/A ACSN
EGFR SHC1 10404636 20430953 23010081 23331499 25987127 26192618 28513565 9710588 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
IGF1R SHC1 10086337 10826997 12175651 12444011 12767520 14764897 16931767 17145802 19030972 21540285 23180781 24103846 24782617 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
SHC1 GAB2 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26192618 26552706 8551221 9763606 interaction type N/A ACSN
CD247 SHC1 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 19229850 20814939 21059766 2139103 23109003 23414611 24445665 26192618 7523143 8344348 8478617 8551221 9603467 9625766 9738502 interaction type,chemical activation reaction N/A ACSN,SignaLink
FCER1G SHC1 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 26192618 7523143 8344348 8478617 8551221 9603467 9625766 9738502 interaction type N/A ACSN
LAT SHC1 10072481 10781611 10811803 11169415 12640133 14764585 16102570 16329184 19494291 19909365 23620508 25137453 26192618 7523143 7890616 8649391 8976179 9489702 9535722 interaction type N/A ACSN
PTK2B SHC1 10679059 10749687 12626562 23180781 26192618 9763606 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
CSF2RB SHC1 23180781 8647804 physical association pull down InnateDB
PTK2 SHC1 10749687 23180781 physical association anti tag coimmunoprecipitation InnateDB
PIN1 SHC1 20354186 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKCD SHC1 16963224 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,protein kinase assay InnateDB
ITGB1 SHC1 19889638 23180781 physical association anti tag coimmunoprecipitation InnateDB
FGFR2 SHC1 18840094 23180781 physical association anti tag coimmunoprecipitation InnateDB
SRC SHC1 10329689 18840094 23109003 23180781 physical association,chemical activation reaction pull down InnateDB,SignaLink
ARHGEF7 SHC1 18385518 23180781 physical association anti tag coimmunoprecipitation InnateDB
FOXO3 SHC1 18385518 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPRE SHC1 18093973 23180781 physical association anti tag coimmunoprecipitation InnateDB
TEK SHC1 14665640 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRS4 SHC1 15316024 23180781 physical association anti tag coimmunoprecipitation InnateDB
EGR1 SHC1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
SHC1 LYN 23180781 7650013 physical association affinity technology InnateDB
SHC1 SHC1 10207047 24737791 26467481 9209406 bind,up-regulates,up-regulates activity N/A Signor
PDGFRB SHC1 21071413 23331499 8195171 stimulation N/A SignaLink,SignaLink
FYN SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 23331499 7516469 9121430 9446569 9710204 9741627 stimulation N/A SignaLink
SHC1 GRAP 23331499 8585965 8995379 stimulation N/A SignaLink
JAK1 SHC1 23331499 9670964 stimulation N/A SignaLink
ERBB2 SHC1 10085134 23331499 9710588 stimulation N/A SignaLink
SHC1 INPP5D 10207047 10822173 23331499 8643691 stimulation N/A SignaLink
IRS1 SHC1 10807918 23331499 7499194 stimulation N/A SignaLink
TGFBR1 SHC1 17673906 23331499 stimulation N/A SignaLink
KDR SHC1 11950700 23331499 stimulation N/A SignaLink
FLT4 SHC1 23331499 9927207 stimulation N/A SignaLink
NTRK1 SHC1 10092678 10629055 23331499 7541035 8155326 8183561 8226808 9856458 stimulation N/A SignaLink
NTRK3 SHC1 10092678 23331499 7657612 stimulation N/A SignaLink
EPHA2 SHC1 12400011 23331499 stimulation N/A SignaLink
LTK SHC1 23331499 9223670 stimulation N/A SignaLink
ALK SHC1 12185581 23331499 stimulation N/A SignaLink
DDR1 SHC1 23331499 9659899 stimulation N/A SignaLink
DDR2 SHC1 11884411 23331499 stimulation N/A SignaLink
RET SHC1 23331499 8183561 9047384 stimulation N/A SignaLink
FGR SHC1 10329689 23109003 chemical activation reaction N/A SignaLink
HCK SHC1 10329689 23109003 chemical activation reaction N/A SignaLink
LYN SHC1 10329689 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
SHC1 PIK3R2 20005715 interaction type N/A PSP
SHC1 PIK3C2B 20005715 interaction type N/A PSP
SHC1 JAK2 20005715 interaction type N/A PSP
SHC1 ABL1 20005715 21071413 8112292 interaction type N/A PSP,SignaLink
SHC1 ESR1 20005715 interaction type N/A PSP
SHC1 ERBB2 16729043 16843263 18988627 20005715 21071413 9710588 interaction type N/A PSP,SignaLink
SHC1 NTRK1 10708759 12446789 20005715 21071413 9856458 interaction type N/A PSP,SignaLink
SHC1 ITGB3 20005715 interaction type N/A PSP
SHC1 INSR 20005715 interaction type N/A PSP
SHC1 LCK 20005715 interaction type N/A PSP
SHC1 FYN 20005715 interaction type N/A PSP
SHC1 CSF1R 20005715 interaction type N/A PSP
SHC1 CD3E 20005715 interaction type N/A PSP,SignaLink
SHC1 LYN 20005715 interaction type N/A PSP
SHC1 RET 20005715 interaction type N/A PSP
SHC1 IGF1R 20005715 interaction type N/A PSP
SHC1 NGFR 20005715 interaction type N/A PSP
SHC1 MET 20005715 interaction type N/A PSP
SHC1 PDGFRB 20005715 interaction type N/A PSP
SHC1 BCR 20005715 interaction type N/A PSP
SHC1 FGFR1 20005715 interaction type N/A PSP,SignaLink
SHC1 FCGR1A 20005715 interaction type N/A PSP,SignaLink
SHC1 SRC 20005715 interaction type N/A PSP
SHC1 IL2RB 10602027 18988627 20005715 21071413 8294403 interaction type N/A PSP,SignaLink
SHC1 ITGB4 20005715 interaction type N/A PSP
SHC1 PLCG2 10623845 20005715 21071413 interaction type N/A PSP,SignaLink
SHC1 PRKCA 20005715 interaction type N/A PSP
SHC1 PLCG1 20005715 interaction type N/A PSP
SHC1 CD247 18988627 20005715 8656061 interaction type N/A PSP,SignaLink
SHC1 CBL 20005715 interaction type N/A PSP
SHC1 MAPK1 20005715 interaction type N/A PSP
SHC1 EPHA2 12400011 18988627 20005715 interaction type N/A PSP,SignaLink
SHC1 PTPN6 20005715 interaction type N/A PSP
SHC1 LTK 20005715 interaction type N/A PSP
SHC1 AXL 20005715 interaction type N/A PSP
SHC1 IL2RG 18988627 20005715 8643566 interaction type N/A PSP,SignaLink
SHC1 FCGR2B 20005715 interaction type N/A PSP
SHC1 CSF2RB 20005715 interaction type N/A PSP
SHC1 FLT4 20005715 interaction type N/A PSP
SHC1 KDR 10319320 10749680 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
SHC1 MPL 20005715 interaction type N/A PSP,SignaLink
SHC1 CSK 20005715 interaction type N/A PSP
SHC1 TEC 20005715 interaction type N/A PSP
SHC1 ZAP70 20005715 interaction type N/A PSP
SHC1 SYK 20005715 interaction type N/A PSP
SHC1 MAPK8 20005715 interaction type N/A PSP
SHC1 CRKL 20005715 interaction type N/A PSP
SHC1 MAPKAPK2 20005715 interaction type N/A PSP
SHC1 TEK 20005715 interaction type N/A PSP
SHC1 MST1R 20005715 interaction type N/A PSP
SHC1 PTK2 20005715 interaction type N/A PSP,SignaLink
SHC1 PRKCD 20005715 interaction type N/A PSP
SHC1 PTPN11 20005715 interaction type N/A PSP
SHC1 PAK1 20005715 interaction type N/A PSP,SignaLink
SHC1 CBLB 20005715 interaction type N/A PSP
SHC1 PTK2B 20005715 interaction type N/A PSP
SHC1 ERBB4 20005715 interaction type N/A PSP
SHC1 NTRK3 20005715 interaction type N/A PSP
SHC1 MAPK14 20005715 interaction type N/A PSP
SHC1 NTRK2 20005715 interaction type N/A PSP
SHC1 DDR2 20005715 interaction type N/A PSP
SHC1 INPP5D 20005715 interaction type N/A PSP,SignaLink
SHC1 MAP4K1 20005715 interaction type N/A PSP
SHC1 ALK 20005715 interaction type N/A PSP
SHC1 CBL 10570290 18988627 20005715 21071413 8621719 8662998 9234717 9461587 N/A N/A SignaLink
SHC1 CBLB 20005715 21071413 9614102 N/A N/A SignaLink
SHC1 CRKL 20005715 21071413 9344843 N/A N/A SignaLink
SHC1 ERBB4 16729043 20005715 21071413 N/A N/A SignaLink
SHC1 IGF1R 16113100 20005715 21071413 7559507 8776723 N/A N/A SignaLink
SHC1 NTRK3 18988627 20005715 7657612 N/A N/A SignaLink
SHC1 SRC 20005715 N/A N/A SignaLink
SHC1 ALK 11888936 18988627 20005715 20005715 21071413 9174053 N/A N/A SignaLink
SHC1 AXL 20005715 20005715 N/A N/A SignaLink
SHC1 BCR 18988627 20005715 20005715 9209414 N/A N/A SignaLink
SHC1 CSF1R 20005715 20005715 N/A N/A SignaLink
SHC1 CSF2RB 10477722 10704825 10704825 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 CSK 10037694 12048194 12048194 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 DDR2 11884411 11884411 11884411 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 ESR1 11773443 11773443 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 FCGR2B 20005715 20005715 21071413 8940017 N/A N/A SignaLink
SHC1 FLT4 18988627 20005715 20005715 21071413 7675451 7970715 7970715 8662748 8662748 8662748 9927207 N/A N/A SignaLink
SHC1 FYN 20005715 20005715 N/A N/A SignaLink
SHC1 INSR 10803466 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 ITGB3 20005715 20005715 N/A N/A SignaLink
SHC1 ITGB4 11044453 18988627 20005715 20005715 N/A N/A SignaLink
SHC1 JAK2 18988627 20005715 20005715 7535773 9126968 N/A N/A SignaLink
SHC1 LCK 20005715 20005715 N/A N/A SignaLink
SHC1 LTK 18988627 20005715 20005715 9223670 N/A N/A SignaLink
SHC1 LYN 18988627 20005715 20005715 21071413 7650013 7650013 N/A N/A SignaLink
SHC1 MAP4K1 20005715 20005715 N/A N/A SignaLink
SHC1 MAPK1 10996427 10996427 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 MAPK14 15688026 18988627 20005715 20005715 N/A N/A SignaLink
SHC1 MAPK8 15688026 18988627 20005715 20005715 N/A N/A SignaLink
SHC1 MAPKAPK2 15094067 15094067 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 MET 18988627 20005715 20005715 21071413 7731718 9660480 N/A N/A SignaLink
SHC1 MST1R 18988627 20005715 20005715 21071413 8918464 8918464 N/A N/A SignaLink
SHC1 NGFR 18988627 20005715 20005715 7541035 N/A N/A SignaLink
SHC1 NTRK2 20005715 20005715 N/A N/A SignaLink
SHC1 PDGFRB 18988627 20005715 20005715 21071413 8195171 8195171 N/A N/A SignaLink
SHC1 PIK3C2B 11533253 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 PIK3R2 20005715 20005715 N/A N/A SignaLink
SHC1 PLCG1 20005715 20005715 N/A N/A SignaLink
SHC1 PRKCA 20005715 20005715 N/A N/A SignaLink
SHC1 PRKCD 12024011 18988627 20005715 20005715 N/A N/A SignaLink
SHC1 PTK2B 20005715 20005715 N/A N/A SignaLink
SHC1 PTPN11 10650943 18988627 20005715 20005715 N/A N/A SignaLink
SHC1 PTPN6 20005715 20005715 N/A N/A SignaLink
SHC1 RET 18988627 20005715 20005715 8183561 9047384 N/A N/A SignaLink
SHC1 SYK 20005715 20005715 N/A N/A SignaLink
SHC1 TEC 11825908 18988627 20005715 20005715 N/A N/A SignaLink
SHC1 TEK 20005715 20005715 N/A N/A SignaLink
SHC1 ZAP70 15688026 18988627 20005715 20005715 21071413 7961936 8761298 9685404 9685404 9685404 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR SHC1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SHC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SHC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SHC1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C SHC1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SHC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SHC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SHC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SHC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SHC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SHC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SIRT1 SHC1 21778425 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 SHC1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003E1A9 SHC1 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000008DA94 SHC1 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000012A1DD SHC1 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS0000171525 SHC1 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000055BBE5 SHC1 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000055BBE5 SHC1 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000008DA94 SHC1 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000171525 SHC1 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003E1A9 SHC1 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000012A1DD SHC1 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002152A8 SHC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000031B6ED SHC1 24216611 25416803 mrna cleavage,inhibition array technology,western blot TarBase
URS0000330617 SHC1 24177325 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SRC SHC1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MAPK14 SHC1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
MET SHC1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCB SHC1 22135298 phosphorylation N/A PhosphoSite
IRS2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 IRS2 25361965 interaction type N/A PTMCode2
EPS8 SHC1 25361965 interaction type N/A PTMCode2
SHC1 EPS8 25361965 interaction type N/A PTMCode2
PLCG2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PLCG2 25361965 interaction type N/A PTMCode2
LCK SHC1 25361965 interaction type N/A PTMCode2
SHC1 LCK 25361965 interaction type N/A PTMCode2
IL2RG SHC1 25361965 interaction type N/A PTMCode2
SHC1 IL2RG 25361965 interaction type N/A PTMCode2
GRAP2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 GRAP2 25361965 interaction type N/A PTMCode2
CSF2RB SHC1 25361965 interaction type N/A PTMCode2
SHC1 CSF2RB 25361965 interaction type N/A PTMCode2
SHCBP1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 SHCBP1 25361965 interaction type N/A PTMCode2
MAPK1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 MAPK1 25361965 interaction type N/A PTMCode2
PRKCD SHC1 25361965 interaction type N/A PTMCode2
SHC1 PRKCD 25361965 interaction type N/A PTMCode2
PTK2B SHC1 25361965 interaction type N/A PTMCode2
SHC1 PTK2B 25361965 interaction type N/A PTMCode2
IL4R SHC1 25361965 interaction type N/A PTMCode2
SHC1 IL4R 25361965 interaction type N/A PTMCode2
CALD1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 CALD1 25361965 interaction type N/A PTMCode2
GHR SHC1 25361965 interaction type N/A PTMCode2
SHC1 GHR 25361965 interaction type N/A PTMCode2
KDR SHC1 25361965 interaction type N/A PTMCode2
SHC1 KDR 25361965 interaction type N/A PTMCode2
NGFR SHC1 25361965 interaction type N/A PTMCode2
SHC1 NGFR 25361965 interaction type N/A PTMCode2
ALK SHC1 25361965 interaction type N/A PTMCode2
SHC1 ALK 25361965 interaction type N/A PTMCode2
FGFR1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 FGFR1 25361965 interaction type N/A PTMCode2
IGF1R SHC1 25361965 interaction type N/A PTMCode2
SHC1 IGF1R 25361965 interaction type N/A PTMCode2
CSK SHC1 25361965 interaction type N/A PTMCode2
SHC1 CSK 25361965 interaction type N/A PTMCode2
IL6ST SHC1 25361965 interaction type N/A PTMCode2
SHC1 IL6ST 25361965 interaction type N/A PTMCode2
CD3E SHC1 25361965 interaction type N/A PTMCode2
SHC1 CD3E 25361965 interaction type N/A PTMCode2
CBL SHC1 25361965 interaction type N/A PTMCode2
SHC1 CBL 25361965 interaction type N/A PTMCode2
PLSCR1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PLSCR1 25361965 interaction type N/A PTMCode2
PSTPIP2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PSTPIP2 25361965 interaction type N/A PTMCode2
CSF3R SHC1 25361965 interaction type N/A PTMCode2
SHC1 CSF3R 25361965 interaction type N/A PTMCode2
SHC1 MET 25361965 interaction type N/A PTMCode2
FYN SHC1 25361965 interaction type N/A PTMCode2
SHC1 FYN 25361965 interaction type N/A PTMCode2
CSF1R SHC1 25361965 interaction type N/A PTMCode2
SHC1 CSF1R 25361965 interaction type N/A PTMCode2
AXL SHC1 25361965 interaction type N/A PTMCode2
SHC1 AXL 25361965 interaction type N/A PTMCode2
MAPK10 SHC1 25361965 interaction type N/A PTMCode2
SHC1 MAPK10 25361965 interaction type N/A PTMCode2
ZAP70 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ZAP70 25361965 interaction type N/A PTMCode2
STAT5A SHC1 25361965 interaction type N/A PTMCode2
SHC1 STAT5A 25361965 interaction type N/A PTMCode2
SOS2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 SOS2 25361965 interaction type N/A PTMCode2
SHC1 AP2A2 25361965 interaction type N/A PTMCode2
AP2A2 SHC1 25361965 interaction type N/A PTMCode2
CD247 SHC1 25361965 interaction type N/A PTMCode2
SHC1 CD247 25361965 interaction type N/A PTMCode2
MAP4K1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 MAP4K1 25361965 interaction type N/A PTMCode2
ITGB3 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ITGB3 25361965 interaction type N/A PTMCode2
LCP2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 LCP2 25361965 interaction type N/A PTMCode2
EPOR SHC1 25361965 interaction type N/A PTMCode2
SHC1 EPOR 25361965 interaction type N/A PTMCode2
AP1B1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 AP1B1 25361965 interaction type N/A PTMCode2
PTPN6 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PTPN6 25361965 interaction type N/A PTMCode2
GAB1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 GAB1 25361965 interaction type N/A PTMCode2
SHC1 SRC 25361965 interaction type N/A PTMCode2
ITGB4 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ITGB4 25361965 interaction type N/A PTMCode2
SOS1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 SOS1 25361965 interaction type N/A PTMCode2
INPPL1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 INPPL1 25361965 interaction type N/A PTMCode2
NTRK2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 NTRK2 25361965 interaction type N/A PTMCode2
YWHAB SHC1 25361965 interaction type N/A PTMCode2
SHC1 YWHAB 25361965 interaction type N/A PTMCode2
PTPN12 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PTPN12 25361965 interaction type N/A PTMCode2
EGFR SHC1 25361965 interaction type N/A PTMCode2
SHC1 EGFR 25361965 interaction type N/A PTMCode2
FCGR2A SHC1 25361965 interaction type N/A PTMCode2
SHC1 FCGR2A 25361965 interaction type N/A PTMCode2
ABL1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ABL1 25361965 interaction type N/A PTMCode2
IRS1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 IRS1 25361965 interaction type N/A PTMCode2
SYK SHC1 25361965 interaction type N/A PTMCode2
SHC1 SYK 25361965 interaction type N/A PTMCode2
GRB2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 GRB2 25361965 interaction type N/A PTMCode2
UBASH3B SHC1 25361965 interaction type N/A PTMCode2
SHC1 UBASH3B 25361965 interaction type N/A PTMCode2
NPM1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 NPM1 25361965 interaction type N/A PTMCode2
EPHA2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 EPHA2 25361965 interaction type N/A PTMCode2
FLT4 SHC1 25361965 interaction type N/A PTMCode2
SHC1 FLT4 25361965 interaction type N/A PTMCode2
SHC1 MAPK14 25361965 interaction type N/A PTMCode2
MPL SHC1 25361965 interaction type N/A PTMCode2
SHC1 MPL 25361965 interaction type N/A PTMCode2
PRKCA SHC1 25361965 interaction type N/A PTMCode2
SHC1 PRKCA 25361965 interaction type N/A PTMCode2
ERBB3 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ERBB3 25361965 interaction type N/A PTMCode2
NTRK3 SHC1 25361965 interaction type N/A PTMCode2
SHC1 NTRK3 25361965 interaction type N/A PTMCode2
CRK SHC1 25361965 interaction type N/A PTMCode2
SHC1 CRK 25361965 interaction type N/A PTMCode2
SPTA1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 SPTA1 25361965 interaction type N/A PTMCode2
DOK2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 DOK2 25361965 interaction type N/A PTMCode2
CRKL SHC1 25361965 interaction type N/A PTMCode2
SHC1 CRKL 25361965 interaction type N/A PTMCode2
TEK SHC1 25361965 interaction type N/A PTMCode2
SHC1 TEK 25361965 interaction type N/A PTMCode2
ERBB2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ERBB2 25361965 interaction type N/A PTMCode2
DNM2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 DNM2 25361965 interaction type N/A PTMCode2
LTK SHC1 25361965 interaction type N/A PTMCode2
SHC1 LTK 25361965 interaction type N/A PTMCode2
AP2A1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 AP2A1 25361965 interaction type N/A PTMCode2
CAD SHC1 25361965 interaction type N/A PTMCode2
SHC1 CAD 25361965 interaction type N/A PTMCode2
FLT1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 FLT1 25361965 interaction type N/A PTMCode2
APP SHC1 25361965 interaction type N/A PTMCode2
SHC1 APP 25361965 interaction type N/A PTMCode2
CDH5 SHC1 25361965 interaction type N/A PTMCode2
SHC1 CDH5 25361965 interaction type N/A PTMCode2
PIK3R1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PIK3R1 25361965 interaction type N/A PTMCode2
RET SHC1 25361965 interaction type N/A PTMCode2
SHC1 RET 25361965 interaction type N/A PTMCode2
JAK2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 JAK2 25361965 interaction type N/A PTMCode2
GAB2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 GAB2 25361965 interaction type N/A PTMCode2
TGFBR2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 TGFBR2 25361965 interaction type N/A PTMCode2
DOK1 SHC1 25361965 interaction type N/A PTMCode2
SHC1 DOK1 25361965 interaction type N/A PTMCode2
INSR SHC1 25361965 interaction type N/A PTMCode2
SHC1 INSR 25361965 interaction type N/A PTMCode2
ERBB4 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ERBB4 25361965 interaction type N/A PTMCode2
IL2RB SHC1 25361965 interaction type N/A PTMCode2
SHC1 IL2RB 25361965 interaction type N/A PTMCode2
PIK3R2 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PIK3R2 25361965 interaction type N/A PTMCode2
BCR SHC1 25361965 interaction type N/A PTMCode2
SHC1 BCR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIK3R2 SHC1 14525934 19380743 24234451 25348397 8662998 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
NUDT21 SHC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KRT6A SHC1 25348397 N/A physical interaction ComPPI
KRT18 SHC1 12577067 14525934 24234451 25348397 colocalization experimental interaction detection,fluorescence microscopy,in vitro ComPPI,HPRD,IntAct
LCP2 SHC1 14525934 24234451 25348397 9716598 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
CDC5L SHC1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA8 SHC1 25348397 N/A physical interaction ComPPI
UBASH3B SHC1 19380743 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
KRT5 SHC1 25348397 N/A physical interaction ComPPI
KRT4 SHC1 25348397 N/A physical interaction ComPPI
KRT2 SHC1 25348397 N/A physical interaction ComPPI
NPM1 SHC1 14525934 25348397 8633037 N/A experimental interaction detection,in vitro ComPPI,HPRD
GRAP SHC1 14525934 24234451 25348397 8995379 association experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
ACTG1 SHC1 25348397 N/A physical interaction ComPPI
TUBB SHC1 25348397 N/A physical interaction ComPPI
FASTKD3 SHC1 20869947 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ACTB SHC1 25348397 N/A physical interaction ComPPI
SMAD4 SHC1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PTPN6 SHC1 14525934 25348397 8541543 N/A experimental interaction detection,in vivo ComPPI,HPRD
KRT77 SHC1 25348397 N/A physical interaction ComPPI
HSP90AB1 SHC1 25348397 N/A physical interaction ComPPI
CRK SHC1 14525934 19380743 23397142 24234451 25348397 8035825 9461587 9837978 association,physical association experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,proximity ligation assay ComPPI,HPRD,IntAct
GEMIN7 SHC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DUSP23 SHC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GRB7 SHC1 14525934 25348397 8940081 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ERBB2 SHC1 14525934 16273093 16729043 16843263 24234451 25348397 9710588 association,physical association experimental interaction detection,protein array,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PAK1 SHC1 25348397 N/A in vitro ComPPI
ERRFI1 SHC1 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CBL SHC1 10570290 14525934 15677445 19380743 24234451 25348397 8621719 8662998 9234717 association,physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
VAV1 SHC1 14525934 15688026 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAPK1 SHC1 10996427 14525934 23584453 24234451 25348397 physical association experimental interaction detection,fluorescent resonance energy transfer,isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SYK SHC1 10482988 14525934 25348397 9096689 9388490 9710204 N/A experimental interaction detection,in vivo ComPPI,HPRD
TEC SHC1 11825908 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IL6ST SHC1 25348397 N/A physical interaction ComPPI
PTK2B SHC1 14525934 25348397 7544443 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TGFBR2 SHC1 17440088 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
CBLB SHC1 14525934 25348397 9614102 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PAG1 SHC1 10790433 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MST1R SHC1 14525934 25348397 8918464 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ERBB4 SHC1 14525934 16273093 16729043 24234451 25348397 physical association experimental interaction detection,protein array,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SP1 SHC1 14525934 25348397 7933095 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK8 SHC1 14525934 15688026 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
KIT SHC1 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
LYN SHC1 14525934 24234451 25348397 7516469 7650013 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PIK3R1 SHC1 14525934 16219545 19380743 23397142 24234451 25348397 8621719 8662998 association,physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification,proximity ligation assay ComPPI,HPRD,IntAct
PTPN11 SHC1 10650943 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCA SHC1 12052829 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SRC SHC1 10482988 14525934 24234451 25348397 26551075 9096689 9388490 9710204 phosphorylation reaction experimental interaction detection,phosphorylation reaction,protein kinase assay,in vivo ComPPI,HPRD,IntAct
FCGR3A SHC1 25348397 27898060 9378963 N/A in vitro ComPPI,OmniPath
CRKL SHC1 14525934 25348397 9344843 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
DOK1 SHC1 11071635 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GRAP2 SHC1 14525934 25348397 9872323 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CD81 SHC1 14525934 14676841 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LCK SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 14525934 25348397 9121430 9446569 9710204 9741627 N/A experimental interaction detection,in vivo ComPPI,HPRD
SH2B2 SHC1 14525934 25348397 9233773 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
INPP5D SHC1 10704825 12024011 14525934 24234451 25348397 8643691 8723348 8874179 N/A experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
FBXW7 SHC1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
VAV3 SHC1 11094073 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FLT1 SHC1 10749680 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
KDR SHC1 10749680 11950700 12214271 14525934 24234451 25348397 association,physical association two hybrid,coimmunoprecipitation,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
PLCG2 SHC1 10623845 12135708 25348397 27898060 N/A physical interaction,in vivo ComPPI,OmniPath
SHC1 PDGFRB 14525934 25348397 8195171 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 EPHA2 12400011 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 ZAP70 14525934 15688026 24234451 25348397 7961936 8761298 9685404 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 PRKCD 12024011 14525934 19380743 24234451 25348397 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SHC1 LRP1 12069755 12789267 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 CD247 14525934 24234451 25348397 7544002 8656061 association experimental interaction detection,nuclear magnetic resonance,in vivo ComPPI,HPRD,IntAct
SHC1 GRB2 11707405 11827484 12213123 12485888 12577067 14525934 15688026 19380743 21706016 21725358 23178716 24189400 24234451 25348397 25416956 7524086 7535773 7798267 8491186 8621719 8663178 8939605 8940013 8995379 9175774 9254595 9544989 9733714 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,tandem affinity purification,bimolecular fluorescence complementation ComPPI,HPRD,IntAct
SHC1 DDR2 11884411 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SHC1 IL2RG 14525934 25348397 8643566 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 BCL3 11707390 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SHC1 PTPN12 11342545 11432829 12052829 14525934 19380743 24189400 24234451 24412244 25348397 7929214 8626541 association,physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
SHC1 EPS8 14525934 25348397 7791787 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 RAPGEF1 14525934 25348397 9344843 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 DDR1 10783152 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 IRS2 11505033 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 INPPL1 14525934 19380743 24234451 25348397 9660833 association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
SHC1 GHR 14525934 25348397 9632636 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 AP2A1 19380743 24189400 24234451 25348397 association physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,IntAct
SHC1 CDH5 11950700 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 PPP2R5A 11884620 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 MAP4K1 14525934 25348397 9346925 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 GAB2 10704825 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 AP2A2 14525934 19380743 24189400 24234451 25348397 8617812 association experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SHC1 PTPN2 25348397 N/A in vitro,in vivo ComPPI
SHC1 PLSCR1 12009895 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 CD3E 11855827 14525934 24234451 25348397 association experimental interaction detection,pull down,in vitro ComPPI,HPRD,IntAct
SHC1 TPR 25348397 N/A in vitro ComPPI
SHC1 SHCBP1 10086341 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SHC1 MAPKAPK2 14525934 15094067 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
SHC1 CEACAM1 11694516 14525934 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
SHC1 CALD1 10559276 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 ITGB3 10964917 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 AXL 14525934 25348397 8610109 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 CALCOCO2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SHC1 MME 14525934 25348397 9659899 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 CSF1R 14525934 25348397 7520523 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 SOS1 14525934 19380743 24234451 25348397 7520523 8631299 9544989 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SHC1 RASA1 14525934 25348397 8155326 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SHC1 MPL 10224114 14525934 25348397 9122198 N/A experimental interaction detection,in vivo ComPPI,HPRD
SHC1 NTRK1 10629055 14525934 24234451 25348397 7541035 8155326 8226808 association coimmunoprecipitation,experimental interaction detection,physical interaction,competition binding,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 NTRK2 12419535 14525934 16034442 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 SOS2 10675333 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 STAT5A 10996427 14525934 23397142 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
SHC1 STAT5B 10996427 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 PLPP3 14525934 16099422 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 CSK 10037694 12048194 14525934 19380743 24234451 25348397 association experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SHC1 DAG1 25348397 N/A physical interaction,in vivo ComPPI
SHC1 MAPK14 14525934 15688026 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SHC1 EGFR 12577067 14525934 15657067 16273093 16729043 20935677 21278788 23178716 23799367 24189400 24234451 25348397 26551075 7518560 7542744 8034616 8662998 8887653 9544989 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,protein array,pull down,x-ray crystallography,phosphorylation reaction,physical interaction,competition binding,protein kinase assay,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
SHC1 EPOR 14525934 25348397 8400282 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 ESR1 11773443 14525934 25348397 N/A anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 FGFR1 25348397 N/A physical interaction,in vitro ComPPI
SHC1 FLT4 14525934 25348397 7675451 8662748 9927207 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 FYN 10482988 10764799 10816433 10896916 10921922 11075717 12237775 14525934 24234451 25348397 7516469 9121430 9446569 9710204 9741627 N/A experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 CSF3R 14525934 25348397 9824671 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 CSF2RB 10477722 10704825 14525934 16437163 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
SHC1 IL2RB 10602027 14525934 25348397 8294403 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 FCGR2A 10382761 14525934 25348397 8940017 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 IRS1 14525934 25348397 7499194 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 ITGB4 11044453 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 INSR 10482988 10764799 10816433 10896916 10921922 11075717 12237775 14525934 15629149 24234451 25348397 8702728 9083103 9121430 9446569 9593725 9710204 9741627 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 IL2 10662798 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHC1 IL4R 10652211 11714803 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 JAK2 14525934 25348397 7535773 9126968 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 BCR 14525934 25348397 9209414 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 LTK 14525934 25348397 9223670 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 NGFR 14525934 25348397 7541035 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 ALK 14525934 25348397 9174053 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SHC1 CD22 10748054 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SHC1 RET 14525934 15677445 24234451 25348397 8183561 9047384 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 MET 14525934 24234451 24728074 25348397 7731718 N/A experimental interaction detection,fluorescence polarization spectroscopy,physical interaction,in vivo ComPPI,HPRD,IntAct
SHC1 ERBB3 14525934 16273093 16729043 24189400 24234451 25348397 9694850 association,physical association experimental interaction detection,protein array,pull down,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
SHC1 DOK2 25348397 N/A physical interaction ComPPI
SHC1 ABL1 25348397 N/A physical interaction ComPPI
SHC1 PTK2 25348397 N/A physical interaction ComPPI
SHC1 PLCG1 10652211 14525934 25348397 8155326 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SHC1 CEACAM5 25348397 N/A physical interaction ComPPI
SHC1 NTRK3 14525934 25348397 7657612 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SHC1 APP 11877420 12485888 14525934 24234451 25348397 9045663 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid ComPPI,HPRD,IntAct
SHC1 GH1 25348397 N/A physical interaction ComPPI
SHC1 PIK3C2B 25348397 N/A physical interaction ComPPI
SHC1 FCGR2B 10382761 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
SHC1 HIF1A 25348397 N/A physical interaction ComPPI
SHC1 HMOX2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHC1 OSGEP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHC1 CBLC 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHC1 ILK 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHC1 SUV39H2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHC1 PRKRA 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHC1 SMAP 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SHC1 LRRK1 24234451 24947832 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SHC1 SPTBN1 25348397 N/A physical interaction ComPPI
SHC1 SPTAN1 25348397 N/A physical interaction ComPPI
SHC1 USP9X 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 KRT1 25348397 N/A physical interaction ComPPI
SHC1 MYH10 25348397 N/A physical interaction ComPPI
SHC1 KRT10 25348397 N/A physical interaction ComPPI
SHC1 KRT9 25348397 N/A physical interaction ComPPI
SHC1 TUBB4B 25348397 N/A physical interaction ComPPI
SHC1 TUBA1B 25348397 N/A physical interaction ComPPI
SHC1 TUBA1C 25348397 N/A physical interaction ComPPI
SHC1 TUBA1A 25348397 N/A physical interaction ComPPI
SHC1 AP2B1 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 USP9Y 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 TUBB2B 25348397 N/A physical interaction ComPPI
SHC1 ACACA 25348397 N/A physical interaction ComPPI
SHC1 ACTN4 25348397 N/A physical interaction ComPPI
SHC1 HSPA1A 25348397 N/A physical interaction ComPPI
SHC1 HSPA1B 25348397 N/A physical interaction ComPPI
SHC1 SPTA1 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 MC1R 25348397 N/A physical interaction ComPPI
SHC1 TUBB3 25348397 N/A physical interaction ComPPI
SHC1 FASN 25348397 N/A physical interaction ComPPI
SHC1 HSPA5 25348397 N/A physical interaction ComPPI
SHC1 MYH9 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 CAD 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 TUBA8 25348397 N/A physical interaction ComPPI
SHC1 PSTPIP2 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 KRT14 25348397 N/A physical interaction ComPPI
SHC1 MYO1D 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 HSPA1L 25348397 N/A physical interaction ComPPI
SHC1 KRT16 25348397 N/A physical interaction ComPPI
SHC1 ACTA1 25348397 N/A physical interaction ComPPI
SHC1 TUBB6 25348397 N/A physical interaction ComPPI
SHC1 HSPA6 25348397 N/A physical interaction ComPPI
SHC1 MYH11 25348397 N/A physical interaction ComPPI
SHC1 ACLY 25348397 N/A physical interaction ComPPI
SHC1 RUVBL2 25348397 N/A physical interaction ComPPI
SHC1 KRT3 25348397 N/A physical interaction ComPPI
SHC1 DNM2 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 HSP90AA1 25348397 N/A physical interaction ComPPI
SHC1 HSP90AA2P 25348397 N/A physical interaction ComPPI
SHC1 RAB3GAP2 25348397 N/A physical interaction ComPPI
SHC1 MYH14 25348397 N/A physical interaction ComPPI
SHC1 PRKDC 25348397 N/A physical interaction ComPPI
SHC1 KRT17 25348397 N/A physical interaction ComPPI
SHC1 AP2M1 19380743 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 ELP1 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 TUBAL3 25348397 N/A physical interaction ComPPI
SHC1 RUVBL1 25348397 N/A physical interaction ComPPI
SHC1 CORO1C 25348397 N/A physical interaction ComPPI
SHC1 TIMM50 25348397 N/A physical interaction ComPPI
SHC1 PRMT5 25348397 N/A physical interaction ComPPI
SHC1 SEC16A 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 DNAJA2 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 PPP1R9B 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 MYO1C 19380743 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 KRT13 25348397 N/A physical interaction ComPPI
SHC1 DNAJA1 25348397 N/A physical interaction ComPPI
SHC1 IARS1 25348397 N/A physical interaction ComPPI
SHC1 S100A8 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 RPS19 25348397 N/A physical interaction ComPPI
SHC1 ATAD3B 25348397 N/A physical interaction ComPPI
SHC1 CCT2 25348397 N/A physical interaction ComPPI
SHC1 AIFM1 25348397 N/A physical interaction ComPPI
SHC1 VARS1 25348397 N/A physical interaction ComPPI
SHC1 S100A9 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 HNRNPH1 25348397 N/A physical interaction ComPPI
SHC1 ARAP1 25348397 N/A physical interaction ComPPI
SHC1 CLTC 25348397 N/A physical interaction ComPPI
SHC1 USP15 25348397 N/A physical interaction ComPPI
SHC1 PRDX1 25348397 N/A physical interaction ComPPI
SHC1 DDX5 25348397 N/A physical interaction ComPPI
SHC1 HAX1 25348397 N/A physical interaction ComPPI
SHC1 CCT6A 25348397 N/A physical interaction ComPPI
SHC1 DDB1 25348397 N/A physical interaction ComPPI
SHC1 S100A7 25348397 N/A physical interaction ComPPI
SHC1 ANXA2P2 25348397 N/A physical interaction ComPPI
SHC1 ANXA2 25348397 N/A physical interaction ComPPI
SHC1 MOV10 25348397 N/A physical interaction ComPPI
SHC1 NXF1 25348397 N/A physical interaction ComPPI
SHC1 RFFL 25348397 N/A physical interaction ComPPI
SHC1 CLIC4 25348397 N/A physical interaction ComPPI
SHC1 PLS3 25348397 N/A physical interaction ComPPI
SHC1 PPP1R8 25348397 N/A physical interaction ComPPI
SHC1 RMDN1 25348397 N/A physical interaction ComPPI
SHC1 STXBP1 25348397 N/A physical interaction ComPPI
SHC1 ARHGAP32 25348397 N/A physical interaction ComPPI
SHC1 CEP170 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SHC1 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SHC1 XPO1 25348397 N/A physical interaction ComPPI
SHC1 TRIM15 25348397 N/A physical interaction ComPPI
SHC1 ARHGEF5 24189400 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 GFAP 25348397 N/A physical interaction ComPPI
SHC1 HNRNPU 25348397 N/A physical interaction ComPPI
SHC1 LGALS3BP 25348397 N/A physical interaction ComPPI
SHC1 PRSS3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 HNRNPA2B1 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SHC1 ITGAV 25348397 N/A physical interaction ComPPI
SHC1 ITGB1 25348397 N/A physical interaction ComPPI
SHC1 SHC2 25348397 N/A physical interaction ComPPI
SHC1 OXT 25348397 N/A physical interaction ComPPI
SHC1 RASAL2 25348397 N/A physical interaction ComPPI
SHC1 CORO2B 25348397 N/A physical interaction ComPPI
SHC1 PEAK1 25348397 N/A physical interaction ComPPI
SHC1 GAREM1 25348397 N/A physical interaction ComPPI
SHC1 CDC25C 25348397 N/A physical interaction ComPPI
SHC1 AMD1 25348397 N/A physical interaction ComPPI
SHC1 AP1B1 25348397 N/A physical interaction ComPPI
SHC1 YWHAZ 11342545 19218246 24234451 25348397 27898060 association coimmunoprecipitation ComPPI,IntAct,OmniPath
SHC1 FCGR1A 24234451 25348397 9716598 phosphorylation reaction experimental interaction detection ComPPI,IntAct
SHC1 TEK 14525934 14665640 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,pull down ComPPI,HPRD,IntAct
SHC1 BUB1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
SHC1 RB1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
SHC1 AR 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SHC1 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
SHC1 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
GAB1 SHC1 12808090 14525934 24234451 24728074 25348397 N/A experimental interaction detection,fluorescence polarization spectroscopy,physical interaction,in vitro ComPPI,HPRD,IntAct
IQGAP1 SHC1 20075861 24234451 25348397 27898060 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
MAPK6 SHC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSPA9 SHC1 25348397 N/A physical interaction ComPPI
IGF1R SHC1 15629149 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MRPL44 SHC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FAM118B SHC1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSPH SHC1 25348397 N/A physical interaction ComPPI
MAT1A SHC1 25348397 N/A physical interaction ComPPI
SHC1 SHC1 19380743 24234451 association tandem affinity purification IntAct
SRC SHC1 10329689 10482988 1409579 15688026 16497976 17016520 17389395 18840094 19901323 20068231 27898060 8939605 9096689 9388490 9566877 9685404 9710204 stimulant N/A OmniPath
SHC1 SRC 10482988 18840094 27898060 8939605 9096689 9388490 9710204 N/A N/A OmniPath
LCK SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 16497976 17016520 17389395 18452278 18578522 18669648 19651622 19664994 19901323 20068231 20230923 27898060 9121430 9446569 9710204 9741627 stimulant N/A OmniPath
PRKCA SHC1 12052829 17924679 18669648 19651622 27898060 N/A N/A OmniPath
NTRK2 SHC1 12419535 16034442 27898060 8808684 stimulant N/A OmniPath
LYN SHC1 27898060 7516469 7650013 stimulant N/A OmniPath
FYN SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 16497976 17016520 17389395 18452278 18578522 18669648 19651622 19664994 19901323 20068231 20230923 27898060 7516469 9121430 9446569 9710204 9741627 stimulant N/A OmniPath
NTRK1 SHC1 10092678 10629055 10708759 12446789 15056278 25921289 27898060 7537849 7541035 8155326 8183561 8226808 8524391 8552402 9715270 9856458 stimulant N/A OmniPath
EGFR SHC1 10049786 10595738 10635327 11350724 11370743 11408594 12218049 12577067 16273093 16729043 18271526 19531499 20935677 23178716 23799367 23956138 24189400 24658140 24797263 25402006 26551075 27898060 7506413 7518560 7537849 7542744 7681824 8034616 8662998 8808684 8887653 9130710 9544989 9722539 9742218 9756944 stimulant N/A OmniPath
PTEN SHC1 10427092 21206972 27898060 inhibition N/A OmniPath
SHC1 PRKCD 12024011 16963224 19380743 27898060 N/A N/A OmniPath
PRKCD SHC1 12024011 16963224 19380743 27898060 stimulant N/A OmniPath
RET SHC1 15677445 16189514 27898060 8183561 9047383 9047384 stimulant N/A OmniPath
ITGB1 SHC1 19889638 27898060 N/A N/A OmniPath
PDGFRB SHC1 27898060 8195171 stimulant N/A OmniPath
PTPN2 SHC1 15588985 27898060 9488479 inhibition N/A OmniPath
HRAS SHC1 17138645 27898060 stimulant N/A OmniPath
JAK3 SHC1 24795043 27898060 stimulant N/A OmniPath
KDR SHC1 10319320 10749680 11950700 12214271 27898060 stimulant N/A OmniPath
FOXO3 SHC1 18385518 27898060 N/A N/A OmniPath
SHC1 FOXO3 15930121 18385518 27898060 inhibition N/A OmniPath
EPHA2 SHC1 12400011 27898060 stimulant N/A OmniPath
SHC1 PIN1 20354186 27898060 N/A N/A OmniPath
IGF1R SHC1 14764897 15629149 16113100 24051437 27898060 7537849 7541045 7559507 8776723 stimulant N/A OmniPath
IL6ST SHC1 27898060 9126968 stimulant N/A OmniPath
IRS1 SHC1 10807918 27898060 7499194 stimulant N/A OmniPath
SHC1 PTK2 10749687 11980671 27898060 stimulant N/A OmniPath
PTK2 SHC1 10725339 10749687 11980671 27898060 stimulant N/A OmniPath
SHC1 SOS1 10025673 10570290 10675333 10783152 19380743 27898060 7520523 8114695 8631299 8950973 9344843 9544989 stimulant N/A OmniPath
SHC1 GRB2 10049786 10080542 10207047 10356320 10477741 10570290 10749687 10961885 11302736 11370743 11505033 11707405 11782427 11792427 11827484 11964172 11997181 12167719 12213123 12441060 12485888 12577067 12898421 1465135 15341520 15688026 15812354 16436051 19380743 20697350 21706016 21725358 22974441 23178716 24189400 24737791 25416956 27898060 7514169 7524086 7535773 7537740 7538132 7717978 7798267 8112292 8114695 8195171 8294403 8491186 8621719 8647288 8662733 8662998 8663178 8808684 8939605 8940013 8950973 8995379 9045692 9083103 9126968 9129019 9175774 9199344 9254595 9434624 9541596 9544989 9566877 9710204 9722539 9733714 9886492 9918770 9927207 stimulant N/A OmniPath
MAPK3 SHC1 15930121 27898060 stimulant N/A OmniPath
JAK1 SHC1 27898060 9670964 stimulant N/A OmniPath
SHC1 PIK3CA 27898060 7537361 stimulant N/A OmniPath
MAPK14 SHC1 15688026 16251354 27898060 N/A N/A OmniPath
ABL1 SHC1 10194451 1623525 19380743 20841568 27898060 8112292 stimulant N/A OmniPath
ERBB2 SHC1 10085134 16273093 16729043 16843263 27898060 8026468 9710588 9756944 stimulant N/A OmniPath
DDR1 SHC1 10783152 27898060 9659899 stimulant N/A OmniPath
FLT3 SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 16497976 17016520 17389395 18452278 18578522 18669648 19651622 19664994 19901323 20068231 20230923 27898060 9096689 9121430 9388490 9446569 9710204 9741627 N/A N/A OmniPath
MET SHC1 11687594 11884620 14685170 14990987 15688026 15708852 18687633 19690143 24728074 27898060 7731718 8084588 8939605 8947042 9083103 stimulant N/A OmniPath
INSR SHC1 10482988 10764799 10803466 10816433 10896916 10921922 11075717 12237775 15629149 16497976 17016520 17389395 18452278 18578522 18669648 19651622 19664994 19901323 20068231 20230923 27898060 7499194 7537849 7559507 8626723 8702728 9083103 9121430 9446569 9593725 9710204 9741627 stimulant N/A OmniPath
MAPK8 SHC1 11075717 15688026 15837797 16251354 27898060 8610109 9741627 stimulant N/A OmniPath
TGFBR1 SHC1 17673906 27898060 stimulant N/A OmniPath
ZAP70 SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 15688026 16497976 17016520 17389395 18452278 18578522 18669648 19651622 19664994 19901323 20068231 20230923 23267066 27898060 7961936 8761298 9096689 9121430 9388490 9446569 9685404 9710204 9741627 stimulant N/A OmniPath
PTPRE SHC1 18093973 27898060 N/A N/A OmniPath
CBLB SHC1 11375397 27898060 9614102 inhibition N/A OmniPath
SHC1 CSF2RB 10477722 10704825 27898060 8647804 N/A N/A OmniPath
CSF2RB SHC1 10477722 10704825 27898060 8647804 stimulant N/A OmniPath
NTRK3 SHC1 10092678 27898060 7657612 stimulant N/A OmniPath
SHC1 TEK 14665640 27898060 N/A N/A OmniPath
TEK SHC1 14665640 27898060 stimulant N/A OmniPath
SHC1 INPP5D 10194451 10207047 10704825 10822173 10900203 11970986 12008030 12024011 15470047 20697350 27898060 8643691 8723348 8874179 9083021 9099679 9393882 stimulant N/A OmniPath
LTK SHC1 27898060 9223670 stimulant N/A OmniPath
ARHGEF7 SHC1 18385518 27898060 N/A N/A OmniPath
IL2RB SHC1 10602027 24737791 27898060 8294403 8643566 stimulant N/A OmniPath
SYK SHC1 10482988 10598576 10891441 11075717 11687594 12237775 15688026 16251354 16477370 16497976 17016520 17389395 19901323 20068231 24552815 27898060 9096689 9121430 9388490 9685404 9710204 9741627 9813159 stimulant N/A OmniPath
FGFR2 SHC1 18840094 27898060 N/A N/A OmniPath
IRS4 SHC1 15316024 27898060 N/A N/A OmniPath
SHC1 GRAP 27898060 8585965 8995379 stimulant N/A OmniPath
PTK2B SHC1 10749687 27898060 7544443 stimulant N/A OmniPath
FLT4 SHC1 27898060 7675451 7970715 8662748 9927207 stimulant N/A OmniPath
ALK SHC1 12185581 27898060 9174053 stimulant N/A OmniPath
RBP1 SHC1 10995764 11313948 12242309 27898060 stimulant N/A OmniPath
PTPN12 SHC1 11342545 11432829 12052829 19380743 24189400 24412244 27898060 7929214 8626541 8939605 inhibition N/A OmniPath
DDR2 SHC1 11884411 16186108 27898060 stimulant N/A OmniPath

Visualization










  Return