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GENE：SLA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLA2
FullNmae Src like adaptor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17329
EnsembleID ENSG00000101082
Uniprot Q9H6Q3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLA2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLA2 GO:0000122,GO:0005515,GO:0005654,GO:0005737,GO:0005770,GO:0005794,GO:0005829,GO:0005886,GO:0005942,GO:0010008,GO:0019724,GO:0035591,GO:0042110,GO:0043231,GO:0046854,GO:0046935,GO:0050776,GO:0050849,GO:0050851,GO:0050860

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SLA2 ERBB2 20005715 interaction type N/A PSP,SignaLink
SLA2 CD247 20005715 interaction type N/A PSP
SLA2 CBL 11891219 12024036 18988627 20005715 21071413 interaction type N/A PSP,SignaLink
SLA2 ZAP70 11891219 18988627 20005715 interaction type N/A PSP,SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 SLA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SLA2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SLA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SLA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SLA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SLA2 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SLA2 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 SLA2 25361965 interaction type N/A PTMCode2
SLA2 CD247 25361965 interaction type N/A PTMCode2
CD247 SLA2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PRKAA2 SLA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBASH3A SLA2 25348397 N/A two hybrid ComPPI
ERBB2 SLA2 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
CBL SLA2 11891219 12024036 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
KIT SLA2 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
ZAP70 SLA2 11891219 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SLA2 CD247 11891219 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SLA2 CSF1 25348397 N/A physical interaction ComPPI
SLA2 LAMC2 25348397 N/A physical interaction ComPPI
SLA2 ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SLA2 EGFR 24234451 24658140 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
SLA2 MET 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
GAB1 SLA2 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
AURKA SLA2 10087264 27898060 N/A N/A OmniPath
PKN1 SLA2 20159853 27898060 N/A N/A OmniPath

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