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GENE：SOCS3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SOCS3
FullNmae suppressor of cytokine signaling 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19391
EnsembleID ENSG00000184557
Uniprot O14543

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SOCS3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SOCS3 GO:0001784,GO:0004860,GO:0005515,GO:0005829,GO:0005942,GO:0009898,GO:0016567,GO:0030292,GO:0035198,GO:0035556,GO:0042532,GO:0043066,GO:0045597,GO:0046426,GO:0046627,GO:0046854,GO:0046935,GO:0050728,GO:0060670,GO:0060674,GO:0072540,GO:0097398,GO:1990830

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SOCS3 hsa:9021 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04930 Type II diabetes mellitus - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04931 Insulin resistance - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa05160 Hepatitis C - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa05164 Influenza A - Homo sapiens (human)
SOCS3 hsa:9021 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRAF6 SOCS3 16543409 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOCS3 MAP3K7 16543409 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL2RB SOCS3 10373548 23180781 physical association gst pull down InnateDB
SOCS2 SOCS3 16199887 23180781 physical association his pull down InnateDB
ELOC SOCS3 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
ELOB SOCS3 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF7 SOCS3 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUL5 SOCS3 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
JAK3 SOCS3 15385932 23180781 physical association anti tag coimmunoprecipitation InnateDB
TFDP1 SOCS3 18687693 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
SOCS3 TFDP3 18687693 23180781 physical association anti tag coimmunoprecipitation InnateDB
AXL SOCS3 12470648 23180781 physical association two hybrid InnateDB
SOCS3 JAK1 10373548 16459330 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation,gst pull down InnateDB,SignaLink,SignaLink
CD33 SOCS3 17008544 23180781 physical association pull down InnateDB
SIGLEC7 SOCS3 17138568 23180781 physical association pull down InnateDB
SOCS3 CSF3R 12133942 23180781 physical association anti tag coimmunoprecipitation InnateDB
SOCS3 ELAVL1 23180781 23686487 physical association anti tag coimmunoprecipitation InnateDB
APP SOCS3 21832049 23180781 physical association protein array InnateDB
SOCS3 JAK2 10421843 10551777 10882725 18988627 21071413 23331499 9344848 stimulation N/A SignaLink,SignaLink
SOCS3 STAT5A 11331873 23331499 stimulation N/A SignaLink,SignaLink
SOCS3 PRLR 11713228 18988627 23331499 stimulation N/A SignaLink,SignaLink
SOCS3 STAT4 14559241 23331499 stimulation N/A SignaLink
SOCS3 LEPR 11018044 18708154 21239736 23331499 stimulation N/A SignaLink
SOCS3 IL12RB1 18708154 23331499 stimulation N/A SignaLink
SOCS3 RASA1 11331873 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
SOCS3 JAK2 20005715 interaction type N/A PSP
SOCS3 INSR 20005715 interaction type N/A PSP
SOCS3 CSF1R 20005715 interaction type N/A PSP
SOCS3 IGF1R 20005715 interaction type N/A PSP
SOCS3 IL2RB 20005715 interaction type N/A PSP,SignaLink
SOCS3 JAK1 20005715 interaction type N/A PSP
SOCS3 JAK3 20005715 interaction type N/A PSP
SOCS3 CXCR4 20005715 interaction type N/A PSP
SOCS3 PTPN11 20005715 interaction type N/A PSP
SOCS3 PIN1 20005715 interaction type N/A PSP
SOCS3 PTK2B 20005715 interaction type N/A PSP,SignaLink
SOCS3 CXCR4 12163560 18988627 20005715 N/A N/A SignaLink
SOCS3 IGF1R 11071852 18988627 20005715 21071413 N/A N/A SignaLink
SOCS3 CSF1R 12133942 18988627 20005715 20005715 N/A N/A SignaLink
SOCS3 INSR 11071852 12560330 12560330 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SOCS3 JAK1 20005715 20005715 N/A N/A SignaLink
SOCS3 JAK2 20005715 20005715 N/A N/A SignaLink
SOCS3 JAK3 20005715 20005715 N/A N/A SignaLink
SOCS3 PIN1 20005715 20005715 N/A N/A SignaLink
SOCS3 PTPN11 12403768 12403768 20005715 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 SOCS3 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SOCS3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SOCS3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SOCS3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 SOCS3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SOCS3 18971253 19332118 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SOCS3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 SOCS3 23335796 trascriptional regulation,stimulation inferred by curator TFlink
RELA SOCS3 23335796 trascriptional regulation,stimulation inferred by curator TFlink
SP3 SOCS3 10570957 trascriptional regulation,stimulation inferred by curator TFlink
STAT1 SOCS3 19115200 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 SOCS3 11788008 15184887 19332118 20357037 22179221 23335796 trascriptional regulation,stimulation inferred by curator TFlink
STAT4 SOCS3 14559241 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004DA9DB SOCS3 17622355 22207897 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS00004DA9DB SOCS3 17622355 22207897 23775225 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000006FDD4 SOCS3 22473208 23894411 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000170CF4 SOCS3 25019494 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000338542 SOCS3 23428672 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS00000753AD SOCS3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F SOCS3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001D69F6 SOCS3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 SOCS3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F SOCS3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 SOCS3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 SOCS3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 SOCS3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 SOCS3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 SOCS3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C SOCS3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA SOCS3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C SOCS3 25416803 25888955 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS00000AD002 SOCS3 25416803 28260062 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
LCK SOCS3 22135298 phosphorylation N/A PhosphoSite
JAK2 SOCS3 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
IL12RB2 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 IL12RB2 25361965 interaction type N/A PTMCode2
NONO SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 NONO 25361965 interaction type N/A PTMCode2
MAP1S SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 MAP1S 25361965 interaction type N/A PTMCode2
GHR SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 GHR 25361965 interaction type N/A PTMCode2
IGF1R SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 IGF1R 25361965 interaction type N/A PTMCode2
EPOR SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 EPOR 25361965 interaction type N/A PTMCode2
BCL10 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 BCL10 25361965 interaction type N/A PTMCode2
IRS1 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 IRS1 25361965 interaction type N/A PTMCode2
TRAF6 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 TRAF6 25361965 interaction type N/A PTMCode2
CUL5 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 CUL5 25361965 interaction type N/A PTMCode2
SOCS3 LEPR 25361965 interaction type N/A PTMCode2
LEPR SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 IL6ST 25361965 interaction type N/A PTMCode2
IL6ST SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 JAK1 25361965 interaction type N/A PTMCode2
JAK1 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 IRS2 25361965 interaction type N/A PTMCode2
IRS2 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 JAK2 25361965 interaction type N/A PTMCode2
SOCS3 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 JAK3 25361965 interaction type N/A PTMCode2
JAK3 SOCS3 25361965 interaction type N/A PTMCode2
INSR SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 INSR 25361965 interaction type N/A PTMCode2
IL2RB SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 IL2RB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 SOCS3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CUL5 SOCS3 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOCS3 YES1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SOCS3 PRLR 11713228 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SOCS3 IL6ST 10946280 12403768 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SOCS3 ELOB 10051596 14525934 15601820 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SOCS3 ELOC 10051596 14525934 15601820 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SOCS3 GHR 10585430 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SOCS3 LEPR 11018044 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SOCS3 PPP3CB 11970967 25348397 27898060 N/A in vitro,in vivo ComPPI,OmniPath
SOCS3 CSF3R 12133942 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SOCS3 PTPN11 12403768 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SOCS3 IRS2 14525934 15514089 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SOCS3 JAK1 10707961 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SOCS3 IL2RB 10373548 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SOCS3 JAK3 10373548 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SOCS3 CSNK1E 14525934 15070676 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SOCS3 BCL10 14525934 15213237 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SOCS3 SOCS2 14525934 16199887 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SOCS3 EGFR 12070153 14525934 24234451 24658140 25348397 physical association experimental interaction detection,ubiquitin reconstruction,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SOCS3 EPOR 10882725 12027890 14525934 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SOCS3 RASA1 11331873 14525934 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SOCS3 IGF1R 11071852 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SOCS3 IRS1 12228220 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SOCS3 INSR 11071852 12560330 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SOCS3 JAK2 10421843 14525934 24234451 25348397 9344848 association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SOCS3 CXCR4 12163560 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SOCS3 CSF1R 12133942 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SOCS3 PTK2B 18507841 25348397 27898060 9344848 N/A physical interaction ComPPI,OmniPath
SOCS3 NONO 25348397 N/A physical interaction ComPPI
SOCS3 MAP3K7 25348397 N/A physical interaction ComPPI
SOCS3 TRAF6 25348397 N/A physical interaction ComPPI
SOCS3 MAP3K5 25348397 N/A physical interaction ComPPI
SOCS3 ACADVL 22093833 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SOCS3 PTK2 16007195 18031698 25348397 25416956 27898060 N/A physical interaction ComPPI,OmniPath
SOCS3 MAPK11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 PDPK1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 MAPK6 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 VHL 25348397 N/A physical interaction ComPPI
SOCS3 DAB1 25348397 N/A physical interaction ComPPI
SOCS3 ETV6 25348397 N/A physical interaction ComPPI
SOCS3 MAPK8IP1 25348397 N/A physical interaction ComPPI
SOCS3 CUEDC2 25348397 N/A physical interaction ComPPI
SOCS3 MAP1S 19027008 24234451 25348397 27898060 colocalization,physical association two hybrid,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
SOCS3 IL12RB2 14559241 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
SOCS3 SIGLEC7 25348397 N/A physical interaction ComPPI
SOCS3 FGFR3 25348397 N/A physical interaction ComPPI
SOCS3 NFKB1 25348397 N/A physical interaction ComPPI
SOCS3 RELA 25348397 N/A physical interaction ComPPI
SOCS3 REL 25348397 N/A physical interaction ComPPI
SOCS3 NFKBIA 25348397 N/A physical interaction ComPPI
SOCS3 TNFSF10 25348397 N/A physical interaction ComPPI
SOCS3 LCK 25348397 N/A physical interaction ComPPI
SOCS3 TFDP1 25348397 N/A physical interaction ComPPI
SOCS3 APP 25348397 N/A physical interaction ComPPI
SOCS3 RNF7 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOCS3 ABL1 25348397 N/A physical interaction ComPPI
SOCS3 NME4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 HIVEP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 RPL7A 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 RBMX 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 BIK 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 GFRA1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SOCS3 TFR2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 TES 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 TXNDC11 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 RNF31 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOCS3 ELAVL1 25348397 N/A physical interaction ComPPI
SOCS3 KIAA1958 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SOCS3 PTK6 25348397 N/A physical interaction ComPPI
SOCS3 TBK1 25348397 N/A physical interaction ComPPI
SOCS3 SH2D2A 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
SOCS3 TRDN 25348397 N/A physical interaction ComPPI
SOCS3 YWHAQ 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SOCS3 AMBRA1 25348397 N/A physical interaction ComPPI
SOCS3 RGP1 25348397 N/A physical interaction ComPPI
SOCS3 AR 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SOCS3 GAB1 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SOCS3 KIT 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SOCS3 MET 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
SOCS3 PKM 25348397 N/A protein kinase assay ComPPI
SOCS3 SNAI1 24234451 25203322 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
SOCS3 BLK 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SOCS3 IDO1 19088199 27898060 N/A N/A OmniPath
LCK SOCS3 12783885 15173187 16352613 27898060 stimulant N/A OmniPath
SOCS3 MAP3K7 16543409 27898060 N/A N/A OmniPath
MAP3K7 SOCS3 16543409 27898060 N/A N/A OmniPath
SOCS3 IFNGR1 14525967 27898060 inhibition N/A OmniPath
SOCS3 CSF3R 12133942 17312100 27898060 inhibition,stimulant N/A OmniPath
CSF3R SOCS3 12133942 27898060 N/A N/A OmniPath
SOCS3 JAK3 10373548 15385932 21508344 27898060 inhibition N/A OmniPath
JAK3 SOCS3 10373548 15385932 27898060 stimulant N/A OmniPath
ELAVL1 SOCS3 23686487 27898060 N/A N/A OmniPath
SOCS3 APP 21832049 27898060 N/A N/A OmniPath
APP SOCS3 21832049 27898060 N/A N/A OmniPath
SOCS3 IL6ST 10777583 10946280 12403768 23663276 27898060 inhibition N/A OmniPath
SOCS3 STAT5A 11331873 27898060 inhibition,stimulant N/A OmniPath
SOCS3 TRAF6 16543409 18055217 27898060 inhibition N/A OmniPath
TRAF6 SOCS3 16543409 27898060 N/A N/A OmniPath
SOCS3 LIFR 17312100 27898060 inhibition N/A OmniPath
SOCS3 IL6R 17312100 27898060 inhibition N/A OmniPath
SOCS3 IRS1 12228220 23115649 27898060 inhibition N/A OmniPath
SOCS3 LEPR 11018044 18708154 21239736 27898060 inhibition,stimulant N/A OmniPath
SOCS3 JAK1 10373548 10707961 16459330 27898060 inhibition,stimulant N/A OmniPath
JAK1 SOCS3 10373548 10707961 16459330 27898060 stimulant N/A OmniPath
SOCS3 MAPK8IP1 18055217 27898060 inhibition N/A OmniPath
SOCS3 PRLR 11713228 27898060 inhibition,stimulant N/A OmniPath
SOCS3 JAK2 10421843 10551777 10882725 11314018 15143188 15514089 19543316 22342841 23454976 24354892 27898060 9344848 inhibition,stimulant N/A OmniPath
SOCS3 STAT4 14559241 27898060 stimulant N/A OmniPath
SOCS3 RNF7 15601820 27898060 N/A N/A OmniPath
SOCS3 IL12RB1 18708154 27898060 inhibition,stimulant N/A OmniPath
SOCS2 SOCS3 16199887 27898060 N/A N/A OmniPath
SOCS3 SOCS2 16199887 27898060 N/A N/A OmniPath
SOCS3 TFDP3 18687693 27898060 N/A N/A OmniPath
SOCS3 ELOC 10051596 12783885 15601820 17135358 18590740 19385048 22084247 27898060 9869640 N/A N/A OmniPath
SOCS3 ELOB 10051596 15601820 16007195 17135358 18590740 19385048 27898060 9869640 N/A N/A OmniPath
SOCS3 RASA1 11331873 27898060 stimulant N/A OmniPath
SOCS3 IL2RB 10373548 27898060 inhibition N/A OmniPath
SOCS3 CD33 17008544 27898060 N/A N/A OmniPath
SOCS3 SIGLEC7 17138568 27898060 N/A N/A OmniPath
SOCS3 CUL5 15601820 17135358 18590740 19385048 27898060 N/A N/A OmniPath
SOCS3 TFDP1 18687693 27898060 inhibition N/A OmniPath
AXL SOCS3 12470648 27898060 N/A N/A OmniPath

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