GENE：ST3GAL4
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ST3GAL4 |
| FullNmae | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10864 |
| EnsembleID | ENSG00000110080 |
| Uniprot | Q11206 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ST3GAL4 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ST3GAL4 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ST3GAL4 | GO:0000139,GO:0003836,GO:0003836,GO:0003836,GO:0005576,GO:0006486,GO:0006486,GO:0008118,GO:0008118,GO:0008373,GO:0009101,GO:0009247,GO:0009247,GO:0009312,GO:0009312,GO:0016020,GO:0016266,GO:0018146,GO:0019082,GO:0030194,GO:0030259,GO:0032580,GO:0047288,GO:0047288,GO:0050890,GO:0097503,GO:1903238,GO:1990743 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ST3GAL4 | hsa:6484 | path:hsa00601 | Glycosphingolipid biosynthesis - lacto and neolacto series - Homo sapiens (human) |
| ST3GAL4 | hsa:6484 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ST3GAL4 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ST3GAL4 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA1 | ST3GAL4 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ST3GAL4 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | ST3GAL4 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ST3GAL4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | ST3GAL4 | 22547830 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ARHGDIA | ST3GAL4 | 14525934 16169070 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| AVP | ST3GAL4 | 25348397 | N/A | physical interaction | ComPPI |
| PLAUR | ST3GAL4 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | ST3GAL4 | 25348397 | N/A | physical interaction | ComPPI |
| CRP | ST3GAL4 | 25348397 | N/A | physical interaction | ComPPI |
| ST3GAL4 | IDS | 25348397 | N/A | physical interaction | ComPPI |
| ST3GAL4 | PCSK1N | 25348397 | N/A | physical interaction | ComPPI |
| ST3GAL4 | PTCH1 | 25348397 | N/A | physical interaction | ComPPI |