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GENE：STT3A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol STT3A
FullNmae STT3 oligosaccharyltransferase complex catalytic subunit A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6172
EnsembleID ENSG00000134910
Uniprot P46977

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
STT3A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
STT3A GO:0004579,GO:0004579,GO:0004579,GO:0005515,GO:0005789,GO:0005789,GO:0006487,GO:0006487,GO:0008250,GO:0008250,GO:0008250,GO:0016020,GO:0018279,GO:0018279,GO:0018279,GO:0035000,GO:0043686,GO:0043687,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
STT3A hsa:3703 path:hsa00510 N-Glycan biosynthesis - Homo sapiens (human)
STT3A hsa:3703 path:hsa00513 Various types of N-glycan biosynthesis - Homo sapiens (human)
STT3A hsa:3703 path:hsa01100 Metabolic pathways - Homo sapiens (human)
STT3A hsa:3703 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRAK2 STT3A 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
SARM1 STT3A 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
STING1 STT3A 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
UNC93B1 STT3A 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 STT3A 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 STT3A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 STT3A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 STT3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 STT3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS STT3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 STT3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF STT3A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE STT3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005FDE70 STT3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 STT3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 STT3A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039607D STT3A 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D STT3A 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 STT3A 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RPN1 STT3A 25361965 interaction type N/A PTMCode2
STT3A RPN1 25361965 interaction type N/A PTMCode2
DAD1 STT3A 25361965 interaction type N/A PTMCode2
STT3A DAD1 25361965 interaction type N/A PTMCode2
DDOST STT3A 25361965 interaction type N/A PTMCode2
STT3A DDOST 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
DERL2 STT3A 25348397 N/A physical interaction ComPPI
NTRK1 STT3A 25348397 N/A physical interaction ComPPI
CANX STT3A 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
TIRAP STT3A 21903422 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HNRNPL STT3A 25348397 N/A physical interaction ComPPI
EGFR STT3A 25348397 N/A physical interaction ComPPI
RAB11A STT3A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
USF1 STT3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IRAK2 STT3A 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB9A STT3A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TFEB STT3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELAVL1 STT3A 25348397 N/A physical interaction ComPPI
TGOLN2 STT3A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AURKAIP1 STT3A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 STT3A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FAF2 STT3A 25348397 N/A physical interaction ComPPI
CSDE1 STT3A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ITM2C STT3A 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HJURP STT3A 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
STT3A SARM1 25348397 N/A physical interaction ComPPI
STT3A STING1 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STT3A UNC93B1 25348397 N/A physical interaction ComPPI
STT3A FBXO6 25348397 N/A physical interaction ComPPI
STT3A OST4 25348397 N/A physical interaction ComPPI
STT3A KRTCAP2 25348397 N/A physical interaction ComPPI
STT3A HAUS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STT3A TMEM258 25348397 N/A physical interaction ComPPI
STT3A EDEM3 25348397 N/A physical interaction ComPPI
STT3A E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
STT3A COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
STT3A LAMP1 24234451 25348397 29568061 association pull down ComPPI,IntAct
HSCB STT3A 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
METTL14 STT3A 24234451 29507755 association anti tag coimmunoprecipitation IntAct
CLN6 STT3A 24234451 30177828 association anti tag coimmunoprecipitation IntAct
RPN1 STT3A 24234451 30021884 physical association cross-linking study IntAct
STING1 STT3A 21903422 27898060 N/A N/A OmniPath

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