GENE:TAPBP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TAPBP |
| FullNmae | TAP binding protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11566 |
| EnsembleID | ENSG00000231925 |
| Uniprot | O15533 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TAPBP | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TAPBP | GO:0000139,GO:0002398,GO:0002502,GO:0002502,GO:0005515,GO:0005789,GO:0006890,GO:0010468,GO:0019885,GO:0023024,GO:0030670,GO:0033116,GO:0042288,GO:0042605,GO:0042824,GO:0042824,GO:0042824,GO:0046978,GO:0046978,GO:0046978,GO:0046979,GO:0046979,GO:0046979,GO:0050823,GO:0051082,GO:0060090,GO:0061635,GO:0061779,GO:0062061,GO:0062061,GO:0065003,GO:0098553 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| TAPBP | hsa:6892 | path:hsa04612 | Antigen processing and presentation - Homo sapiens (human) |
| TAPBP | hsa:6892 | path:hsa05163 | Human cytomegalovirus infection - Homo sapiens (human) |
| TAPBP | hsa:6892 | path:hsa05168 | Herpes simplex virus 1 infection - Homo sapiens (human) |
| TAPBP | hsa:6892 | path:hsa05169 | Epstein-Barr virus infection - Homo sapiens (human) |
| TAPBP | hsa:6892 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| IRF1 | TAPBP | 18694960 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| RELA | TAPBP | 18694960 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| PRDM1 | TAPBP | 20421211 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | TAPBP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | TAPBP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| IRF1 | TAPBP | 18694960 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFKB1 | TAPBP | 18694960 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RELA | TAPBP | 18694960 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000065D58 | TAPBP | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00000EC1BE | TAPBP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000035CC3E | TAPBP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000005481D | TAPBP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001A405B | TAPBP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000057A7C | TAPBP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000254A6 | TAPBP | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | TAPBP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | TAPBP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | TAPBP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005586D0 | TAPBP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028C188 | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000043F369 | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000047E28E | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001EB3 | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDE70 | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000072B4C8 | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000006DA05 | TAPBP | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TAP2 | TAPBP | 12213826 14525934 16828748 19201886 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| TAP1 | TAPBP | 12213826 14525934 16828748 17055437 18802093 19201886 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| PDIA3 | TAPBP | 17170699 24234451 25348397 | disulfide bond | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TAPBP | COPB1 | 11884415 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| TAPBP | COPG2 | 11884415 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| TAPBP | COPG1 | 11884415 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| TAPBP | CALR | 14525934 24234451 25348397 30021884 8769474 | physical association | cross-linking study,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| TAPBP | HLA-A | 14525934 24163410 24234451 25348397 26439010 8769474 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,fluorescence polarization spectroscopy,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| TAPBP | B2M | 25348397 | N/A | physical interaction | ComPPI |
| TAPBP | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| TAPBP | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| TAPBP | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| TAPBP | HTR2C | 25348397 | N/A | physical interaction | ComPPI |
| TAPBP | UBC | 25348397 | N/A | physical interaction | ComPPI |
| TAPBP | HLA-C | 14525934 8769474 | N/A | experimental interaction detection | HPRD |
| TAPBP | CALR | 10618487 27898060 8769474 | N/A | N/A | OmniPath |
| CALR | TAPBP | 10618487 27898060 8769474 | N/A | N/A | OmniPath |
| TAPBP | TAP1 | 10618487 11884415 12213826 16828748 17055437 27898060 | N/A | N/A | OmniPath |
| TAP1 | TAPBP | 10618487 11884415 12213826 16828748 17055437 27898060 | N/A | N/A | OmniPath |
| TAPBP | PDIA3 | 10618487 17170699 27898060 | N/A | N/A | OmniPath |
| PDIA3 | TAPBP | 10618487 17170699 27898060 | N/A | N/A | OmniPath |
| B2M | TAPBP | 10618487 27898060 | N/A | N/A | OmniPath |
| TAPBP | TAP2 | 10618487 12213826 16828748 27898060 | N/A | N/A | OmniPath |
| TAP2 | TAPBP | 10618487 12213826 16828748 27898060 | N/A | N/A | OmniPath |
