GENE:TNFSF13B
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | TNFSF13B |
FullNmae | TNF superfamily member 13b |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:11929 |
EnsembleID | ENSG00000102524 |
Uniprot | Q9Y275 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
TNFSF13B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
TNFSF13B | GO:0001782,GO:0002467,GO:0002636,GO:0005102,GO:0005125,GO:0005164,GO:0005515,GO:0005576,GO:0005615,GO:0005737,GO:0005886,GO:0005925,GO:0007165,GO:0016020,GO:0030183,GO:0030890,GO:0030890,GO:0030890,GO:0031295,GO:0031296,GO:0033209,GO:0042098,GO:0042100,GO:0042102,GO:0043231,GO:0048018,GO:0048471 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
TNFSF13B | hsa:10673 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
TNFSF13B | hsa:10673 | path:hsa04064 | NF-kappa B signaling pathway - Homo sapiens (human) |
TNFSF13B | hsa:10673 | path:hsa04672 | Intestinal immune network for IgA production - Homo sapiens (human) |
TNFSF13B | hsa:10673 | path:hsa05323 | Rheumatoid arthritis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AHR | TNFSF13B | 17823304 17900530 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
TNFSF13B | REL | 17567982 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TNFSF13B | CD40 | 16644731 17567982 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
TNFSF13 | TNFSF13B | 12370363 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
TNFRSF17 | TNFSF13B | 12571250 23180781 | physical association | surface plasmon resonance | InnateDB |
TNFRSF13C | TNFSF13B | 12571250 23180781 | physical association | surface plasmon resonance | InnateDB |
TNFSF13B | TNFSF13B | 15644327 15851487 26467481 | bind,up-regulates activity | N/A | Signor |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TP53 | TNFSF13B | 18922183 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | TNFSF13B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | TNFSF13B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | TNFSF13B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | TNFSF13B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | TNFSF13B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | TNFSF13B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
NFKB1 | TNFSF13B | 16497967 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT1 | TNFSF13B | 23271704 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000F31F4 | TNFSF13B | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | TNFSF13B | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00003D8730 | TNFSF13B | 25416803 25971527 26689580 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS0000065D58 | TNFSF13B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS000005CF5F | TNFSF13B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00001DE669 | TNFSF13B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
HLA-DPB1 | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
ITGA7 | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
ITGB1 | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
ITGAV | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
NUP85 | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
MAP3K5 | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
PIGQ | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
FANCD2 | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
TNFRSF17 | TNFSF13B | 10801128 10908663 10973284 14525934 24234451 25348397 | physical association | experimental interaction detection,physical interaction,saturation binding,in vitro,in vivo | ComPPI,HPRD,IntAct |
TNFSF13B | TNFRSF13B | 10801128 10880535 10956646 14525934 24234451 25348397 | physical association | anti tag coimmunoprecipitation,experimental interaction detection,fluorescence-activated cell sorting,surface plasmon resonance,physical interaction,biochemical,saturation binding,in vitro,in vivo | ComPPI,HPRD,IntAct |
TNFSF13B | TNFRSF13C | 11509692 12721620 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
TNFSF13B | TNFSF13 | 12370363 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD,OmniPath |
TNFSF13B | APP | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | TNFSF12 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | CAND2 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | IPO7 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | PDSS1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | MON2 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | RANBP6 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | MFAP3 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | FHIP2A | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | BPNT2 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | HOOK2 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | TTC17 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | HOOK1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | BRAT1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | LRIG3 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | IPO8 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | MAP3K6 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | MAP3K15 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | IPO11 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | TMEM131 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | HEATR1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | TNPO2 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | NF1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | IPO9 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | NCAPG | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | FAM118A | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | SAAL1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | BTAF1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | HOOK3 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | AKTIP | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | FHIP1B | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | PRR35 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | TMEM39A | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | ARSK | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | CHST12 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | VTI1B | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | PXYLP1 | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | DYM | 25348397 | N/A | physical interaction | ComPPI |
XPO4 | TNFSF13B | 25348397 | N/A | physical interaction | ComPPI |
TNFSF13B | TNFSF13B | 11853672 11862220 12721620 14525934 | N/A | experimental interaction detection | HPRD |
TNFSF13B | STAT1 | 23271704 24234451 | association | chromatin immunoprecipitation assay | IntAct |
TNFSF13B | MAP3K14 | 17183360 27898060 | stimulant | N/A | OmniPath |
TNFSF13B | TNFRSF13B | 10801128 10880535 10956646 23493554 27898060 | stimulant | N/A | OmniPath |
TNFSF13B | TNFRSF13C | 11509692 12571250 12721620 15644327 15851487 23493554 27898060 | stimulant | N/A | OmniPath |