Gene Information gene info

GENE:TNNT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNNT1
FullNmae troponin T1, slow skeletal type
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11948
EnsembleID ENSG00000105048
Uniprot P13805

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNNT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TNNT1 GO:0003009,GO:0005515,GO:0005523,GO:0005523,GO:0005829,GO:0005861,GO:0005861,GO:0005861,GO:0014883,GO:0031014,GO:0031444,GO:0045214,GO:0045932

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNNT1 hsa:7138 path:hsa04814 Motor proteins - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TP73 TNNT1 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF TNNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TNNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TNNT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SNW1 TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FXR2 TNNT1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LDOC1 TNNT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNNI3 TNNT1 11904166 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
VIM TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D1 TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPFIA1 TNNT1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCDC85B TNNT1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KRT40 TNNT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSP90AB1 TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LARP1 TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PNMA1 TNNT1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SMURF2 TNNT1 18157088 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMAD1 TNNT1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
OSM TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD2 TNNT1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NFE2L2 TNNT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKG1 TNNT1 10601315 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FAF1 TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NAGK TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DDX5 TNNT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TPM3 TNNT1 25348397 N/A physical interaction ComPPI
MORF4L1 TNNT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSMC5 TNNT1 14525934 16189514 21516116 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MYOM2 TNNT1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TRIM63 TNNT1 18157088 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BMPR1B TNNT1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNNT1 TNNI2 14525934 25348397 9448267 9724539 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
TNNT1 TNNC1 14525934 25348397 8987992 9448267 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
TNNT1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNNT1 NINL 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TNNT1 TPM1 14525934 21516116 24234451 25348397 25416956 27898060 3611073 6822572 8987992 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct,OmniPath
TNNT1 IMMT 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 SH3GL3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 ZNF768 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 KAT5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 EEF1G 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 BLOC1S2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 ZC3H15 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 SERPINA4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 OSBP2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 TRA2A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 TMEM98 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 HAP1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 FYN 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 CHD3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNNT1 TFIP11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNNT1 CCDC136 25348397 N/A physical interaction ComPPI
TNNT1 CLIP4 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TNNT1 TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
TBPL1 TNNT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TGFBR1 TNNT1 14525934 15761153 N/A experimental interaction detection HPRD
H1-5 TNNT1 24234451 30021884 physical association cross-linking study IntAct

Visualization