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GENE：USF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USF2
FullNmae upstream transcription factor 2, c-fos interacting
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12594
EnsembleID ENSG00000105698
Uniprot Q15853

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USF2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
USF2 GO:0000430,GO:0000432,GO:0000432,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006357,GO:0007595,GO:0019086,GO:0042803,GO:0043231,GO:0043425,GO:0043565,GO:0045944,GO:0046982,GO:0055088,GO:1990837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
B2M USF2 12480693 23180781 physical association electrophoretic mobility supershift assay,electrophoretic mobility shift assay,enzymatic study InnateDB
USF2 CXCR4 10229837 23180781 physical association electrophoretic mobility supershift assay InnateDB
USF2 HOXB4 11085749 23180781 physical association electrophoretic mobility supershift assay InnateDB
USF2 PLA2G4C 22082005 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 USF2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TP53 USF2 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 USF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA USF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 USF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EPAS1 USF2 23991099 trascriptional regulation,stimulation inferred by curator TFlink
SP1 USF2 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP3 USF2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000016D2D4 USF2 19074828 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000085F64 USF2 23280316 rna interference,inhibition western blot miRSponge
URS000016D2D4 USF2 19074828 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000085F64 USF2 23280316 25416803 mrna cleavage,inhibition western blot TarBase
URS0000237AF9 USF2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003FD55 USF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD USF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 USF2 25074381 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003AD2AA USF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 USF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 USF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004A9320 USF2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B USF2 22135298 phosphorylation N/A PhosphoSite
USF2 FASN 25361965 interaction type N/A PTMCode2
FASN USF2 25361965 interaction type N/A PTMCode2
USF2 FOS 25361965 interaction type N/A PTMCode2
FOS USF2 25361965 interaction type N/A PTMCode2
USF2 MAF 25361965 interaction type N/A PTMCode2
MAF USF2 25361965 interaction type N/A PTMCode2
USF2 USF1 25361965 interaction type N/A PTMCode2
USF1 USF2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TFAP4 USF2 25348397 N/A physical interaction ComPPI
CDC42 USF2 25348397 N/A two hybrid ComPPI
LZTS2 USF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NPM1 USF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MAF USF2 14525934 25348397 27898060 9070273 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
NFYA USF2 12791656 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FOSL2 USF2 25348397 N/A physical interaction ComPPI
EP300 USF2 10434034 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
PPARGC1A USF2 12611894 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
RELA USF2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
USF2 USF1 14525934 15014447 16943425 17353931 17846119 18817855 19303849 21653943 24234451 25348397 26496610 27898060 8576131 9053857 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
USF2 BRCA1 14502648 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
USF2 BIRC5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 SERPINB3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 S100A9 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 SERPINB4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 HSPA4L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 PTP4A2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 S100A8 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 FUS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USF2 FOS 14525934 1589769 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
USF2 TEAD2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
USF2 ADAMTS12 25348397 N/A physical interaction ComPPI
USF2 PSG1 25348397 N/A physical interaction ComPPI
USF2 FOXJ2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
USF2 CCDC102B 25348397 N/A physical interaction ComPPI
USF2 CALML5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
USF2 TRPV5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
USF2 SPRR1B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
USF2 RPL3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
USF2 IGHG2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
USF2 USF2 14525934 17353931 24234451 8576131 9070273 physical association anti bait coimmunoprecipitation,experimental interaction detection HPRD,IntAct
GSK3B USF2 25238393 27898060 N/A N/A OmniPath

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