GENE：XCL1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | XCL1 |
| FullNmae | X-C motif chemokine ligand 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10645 |
| EnsembleID | ENSG00000143184 |
| Uniprot | P47992 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| XCL1 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| XCL1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| XCL1 | GO:0001916,GO:0002548,GO:0002690,GO:0002725,GO:0002726,GO:0002826,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0006954,GO:0007165,GO:0007186,GO:0007267,GO:0008009,GO:0008009,GO:0009615,GO:0010820,GO:0010820,GO:0030593,GO:0030593,GO:0032689,GO:0032703,GO:0032733,GO:0035782,GO:0042379,GO:0042379,GO:0042803,GO:0043433,GO:0043547,GO:0045892,GO:0048020,GO:0048245,GO:0048247,GO:0050727,GO:0051209,GO:0051281,GO:0070098,GO:0070374,GO:0071346,GO:0071347,GO:0071353,GO:0071356,GO:0071560,GO:0071636,GO:0071663,GO:0090023,GO:2000412,GO:2000503,GO:2000513,GO:2000518,GO:2000538,GO:2000553,GO:2000556,GO:2000558,GO:2000562,GO:2000563,GO:2000566 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| XCL1 | hsa:6375 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| XCL1 | hsa:6375 | path:hsa04061 | Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human) |
| XCL1 | hsa:6375 | path:hsa04062 | Chemokine signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMARCA4 | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | XCL1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CXCL9 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| COL6A2 | XCL1 | 25348397 | N/A | physical interaction | ComPPI |
| PF4 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding,surface plasmon resonance,surface plasmon resonance array | ComPPI,IntAct |
| CCL5 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding,surface plasmon resonance,surface plasmon resonance array | ComPPI,IntAct |
| CCL13 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CXCL12 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding,surface plasmon resonance,surface plasmon resonance array | ComPPI,IntAct |
| CCL11 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CXCL11 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CCL28 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CCL21 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| XCR1 | XCL1 | 11446740 14525934 25348397 9632725 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| XCL1 | KRTAP10-3 | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | FAT4 | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | TUBB8 | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | MC1R | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | TUBB3 | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | FAT3 | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | ADGRV1 | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | FSTL1 | 25348397 | N/A | physical interaction | ComPPI |
| XCL1 | CCL24 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| XCL1 | PF4V1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| XCL1 | CCL26 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| XCL1 | CXCL2 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| XCL1 | CXCL10 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| XCL1 | CXCL17 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| CXCL14 | XCL1 | 24234451 25348397 28381538 | N/A | filter binding | ComPPI,IntAct |
| XCL1 | VCAN | 11083865 14525934 | N/A | experimental interaction detection | HPRD |
| XCL1 | XCL1 | 11601972 14525934 18364395 24234451 | N/A | experimental interaction detection,nuclear magnetic resonance | HPRD,IntAct |
| XCL1 | XCR1 | 10518929 11446740 24218476 27898060 9632725 | stimulant | N/A | OmniPath |