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GENE：SPRY2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPRY2
FullNmae sprouty RTK signaling antagonist 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11270
EnsembleID ENSG00000136158
Uniprot O43597

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPRY2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SPRY2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SPRY2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPRY2 GO:0000132,GO:0005515,GO:0005634,GO:0005829,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0007605,GO:0008543,GO:0010628,GO:0010719,GO:0010801,GO:0015629,GO:0015630,GO:0016020,GO:0016525,GO:0019901,GO:0030291,GO:0030335,GO:0030512,GO:0031345,GO:0031397,GO:0032587,GO:0033138,GO:0035924,GO:0040037,GO:0042472,GO:0043066,GO:0043407,GO:0043539,GO:0045165,GO:0045742,GO:0046580,GO:0048513,GO:0051387,GO:0051897,GO:0055105,GO:0060437,GO:0060449,GO:0070371,GO:0070373,GO:0070373,GO:0070373,GO:0070374,GO:1900747,GO:1902747,GO:1990752,GO:1990830

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SPRY2 hsa:10253 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SPRY2 GRB2 11447289 11997436 15173823 16339969 17496910 23180781 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
SPRY2 FRS2 11447289 11997436 15173823 17496910 26192618 interaction type N/A ACSN
RAF1 SPRY2 12717443 23180781 physical association anti tag coimmunoprecipitation InnateDB
SPRY2 SPRY4 16339969 23180781 physical association anti tag coimmunoprecipitation InnateDB
SPRY2 SPRY3 16339969 23180781 physical association anti tag coimmunoprecipitation InnateDB
SPRY2 SOS1 16339969 23180781 physical association anti tag coimmunoprecipitation InnateDB
AQP1 SPRY2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
SPRY2 RAF1 20005715 interaction type N/A PSP,SignaLink
SPRY2 CBL 20005715 interaction type N/A PSP
SPRY2 PTPN11 20005715 interaction type N/A PSP,SignaLink
SPRY2 CBLB 20005715 interaction type N/A PSP
SPRY2 CBLC 20005715 interaction type N/A PSP
SPRY2 CBL 11053437 11983899 12234920 12593795 12593796 16246327 16893902 18273061 18988627 20005715 20877636 21071413 21596750 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR SPRY2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SPRY2 14644509 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SPRY2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 SPRY2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SPRY2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 SPRY2 14644509 trascriptional regulation,stimulation inferred by curator TFlink
SP1 SPRY2 14644509 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 SPRY2 14644509 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A SPRY2 14644509 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D SPRY2 18508928 21278789 23239100 \N rna interference,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001B341F SPRY2 20638779 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS000009262D SPRY2 18508928 18927107 21278789 23239100 25416803 25728247 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS00001B341F SPRY2 20638779 23649631 23650389 25416803 mrna cleavage,inhibition array technology,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00003BBF48 SPRY2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000003ABC4 SPRY2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000FFC8B SPRY2 23649631 25416803 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001CC864 SPRY2 23649631 25416803 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003380CC SPRY2 25416803 27943426 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SRC SPRY2 22135298 phosphorylation N/A PhosphoSite
MKNK2 SPRY2 22135298 phosphorylation N/A PhosphoSite
DYRK1A SPRY2 22135298 phosphorylation N/A PhosphoSite
MKNK1 SPRY2 22135298 phosphorylation N/A PhosphoSite
RAF1 SPRY2 25361965 interaction type N/A PTMCode2
SPRY2 RAF1 25361965 interaction type N/A PTMCode2
CBL SPRY2 25361965 interaction type N/A PTMCode2
SPRY2 CBL 25361965 interaction type N/A PTMCode2
SPRY2 SH3KBP1 25361965 interaction type N/A PTMCode2
SH3KBP1 SPRY2 25361965 interaction type N/A PTMCode2
SPRY2 PPP2CA 25361965 interaction type N/A PTMCode2
PPP2CA SPRY2 25361965 interaction type N/A PTMCode2
GRB2 SPRY2 25361965 interaction type N/A PTMCode2
SPRY2 GRB2 25361965 interaction type N/A PTMCode2
TESK1 SPRY2 25361965 interaction type N/A PTMCode2
SPRY2 TESK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP9-2 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STK16 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FRS3 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP10-5 SPRY2 24234451 25348397 25416956 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HEXIM2 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
USP20 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CATSPER1 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 SPRY1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 KRTAP5-9 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 OTX1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 UBASH3A 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 KRTAP10-1 25348397 N/A two hybrid,physical interaction ComPPI
SPRY2 KRTAP10-8 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 LCE3E 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 LCE1B 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 UBASH3B 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 KRTAP4-12 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
SPRY2 KRTAP9-4 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 PACSIN3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 MEOX2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 MDFI 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 CBL 11053437 12234920 12815057 14525934 15962011 16893902 18273061 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,x-ray crystallography,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SPRY2 PTPN11 14525934 15031289 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SPRY2 GRB2 10940627 12402043 14525934 16893902 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,filter binding,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SPRY2 CBLC 12234920 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SPRY2 CBLB 11053437 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SPRY2 TRAF2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPRY2 PLSCR1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPRY2 TRIM51 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPRY2 GPRIN2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPRY2 ADAMTSL4 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPRY2 RAF1 12717443 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SPRY2 TESK1 25348397 N/A physical interaction ComPPI
SPRY2 PPP2CA 25348397 N/A physical interaction ComPPI
SPRY2 SIAH2 25348397 N/A physical interaction ComPPI
SPRY2 NEDD4 25348397 N/A physical interaction ComPPI
SPRY2 EGLN2 25348397 N/A physical interaction ComPPI
SPRY2 EGLN1 25348397 N/A physical interaction ComPPI
SPRY2 EGLN3 25348397 N/A physical interaction ComPPI
SPRY2 VHL 25348397 N/A physical interaction ComPPI
SPRY2 SDHB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 ZNF266 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 ZBTB16 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 UBR1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 FBN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 CTSB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 CRIP2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 DNM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 SEMA5B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 FAM219A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 NUBP1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 CSTB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 CRMP1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 NR1H2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 RTF2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 ITSN1 22158968 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SPRY2 ELAVL1 25348397 N/A physical interaction ComPPI
SPRY2 HRAS 25348397 N/A physical interaction ComPPI
SPRY2 VPS25 25348397 N/A physical interaction ComPPI
SPRY2 VPS36 25348397 N/A physical interaction ComPPI
SPRY2 PPP2R1A 25348397 N/A physical interaction ComPPI
SPRY2 HGS 25348397 N/A physical interaction ComPPI
SPRY2 SPRY4 25348397 N/A physical interaction ComPPI
SPRY2 FRS2 25348397 N/A physical interaction ComPPI
SPRY2 MKNK1 25348397 N/A physical interaction ComPPI
SPRY2 CTNNA3 25348397 N/A physical interaction ComPPI
SPRY2 KDM1A 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPRY2 DGCR6 25348397 N/A physical interaction ComPPI
SPRY2 KIF1A 25348397 N/A physical interaction ComPPI
SPRY2 PRKAB2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 AQP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 RUNX1T1 25348397 N/A physical interaction ComPPI
SPRY2 GP9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 LASP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 MLLT6 25348397 N/A physical interaction ComPPI
SPRY2 PTGER3 25348397 N/A physical interaction ComPPI
SPRY2 CHRD 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 GRAP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 EIF4E2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 CREB5 25348397 N/A physical interaction ComPPI
SPRY2 TCAF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 GNE 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 MID2 25348397 N/A physical interaction ComPPI
SPRY2 MAPKBP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 ZDHHC17 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 FAIM 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 SHFL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 HSD3B7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 TXNDC5 25348397 N/A physical interaction ComPPI
SPRY2 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 ZNF587 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 LONRF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 ZNF417 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 KRTAP10-9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 KRTAP10-3 25348397 N/A physical interaction ComPPI
SPRY2 ZFP36 25348397 N/A physical interaction ComPPI
SPRY2 PLS1 25348397 N/A physical interaction ComPPI
SPRY2 VANGL1 25348397 N/A physical interaction ComPPI
SPRY2 UBE2D2 25348397 N/A physical interaction ComPPI
SPRY2 SNX3 25348397 N/A physical interaction ComPPI
SPRY2 VANGL2 25348397 N/A physical interaction ComPPI
SPRY2 CAB39 25348397 N/A physical interaction ComPPI
SPRY2 TNS2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SPRY2 TMEM14B 25348397 N/A physical interaction ComPPI
SPRY2 HIF1A 25348397 N/A physical interaction ComPPI
SPRY2 S100A13 25348397 N/A physical interaction ComPPI
SPRY2 TES 25348397 N/A physical interaction ComPPI
SPRY2 CTH 25348397 N/A physical interaction ComPPI
SPRY2 BRAF 25348397 N/A physical interaction ComPPI
SPRY2 PRKCD 25348397 N/A physical interaction ComPPI
SPRY2 PRKD1 25348397 N/A physical interaction ComPPI
SPRY2 KRTAP4-7 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SPRY2 GRN 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP10-11 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LCE3C SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LCE4A SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LCE2D SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP5-6 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SH3KBP1 SPRY2 15962011 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
KRTAP4-11 SPRY2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2E3 SPRY2 25348397 N/A physical interaction ComPPI
SPRY2 SPRY2 24234451 25416956 physical association two hybrid array IntAct
SRC SPRY2 12593795 12815057 15564375 16479008 18683950 19864419 27898060 inhibition,stimulant N/A OmniPath
MAPK10 SPRY2 15637081 27898060 N/A N/A OmniPath
SOS1 SPRY2 11585837 16339969 27898060 N/A N/A OmniPath
GRB2 SPRY2 10940627 11585837 12402043 15004239 16339969 16893902 17255109 17974561 27898060 N/A N/A OmniPath
SPRY2 RAF1 12717443 27898060 N/A N/A OmniPath
RAF1 SPRY2 12717443 27898060 N/A N/A OmniPath
PTPN11 SPRY2 15031289 27898060 N/A N/A OmniPath
SPRY2 CBLB 11053437 27898060 inhibition N/A OmniPath
MKNK1 SPRY2 16479008 19690147 19864419 27898060 inhibition,stimulant N/A OmniPath
SPRY4 SPRY2 16339969 27898060 N/A N/A OmniPath
SPRY2 SPRY3 16339969 27898060 N/A N/A OmniPath
DYRK1A SPRY2 12593795 12815057 15637081 16000370 18678649 20804972 27898060 inhibition N/A OmniPath

Visualization










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