GENE：SLC22A3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | SLC22A3 |
| FullNmae | solute carrier family 22 member 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:10967 |
| EnsembleID | ENSG00000146477 |
| Uniprot | O75751 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| SLC22A3 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| SLC22A3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| SLC22A3 | GO:0001692,GO:0005326,GO:0005326,GO:0005515,GO:0005640,GO:0005886,GO:0005886,GO:0006811,GO:0006836,GO:0006837,GO:0008504,GO:0008504,GO:0008514,GO:0012505,GO:0015101,GO:0015101,GO:0015101,GO:0015606,GO:0015651,GO:0015695,GO:0015697,GO:0015711,GO:0015718,GO:0015844,GO:0015848,GO:0015872,GO:0015874,GO:0016020,GO:0016323,GO:0016324,GO:0019534,GO:0031966,GO:0032098,GO:0042908,GO:0043025,GO:0048241,GO:0051608,GO:0051610,GO:0051615,GO:0051615,GO:0051620,GO:0051625,GO:0072530,GO:0090494,GO:0098793,GO:0150104,GO:1901998,GO:1903711 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| SLC22A3 | hsa:6581 | path:hsa05231 | Choline metabolism in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | SLC22A3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA2 | SLC22A3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | SLC22A3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | SLC22A3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | SLC22A3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | SLC22A3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | SLC22A3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | SLC22A3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| KLF8 | SLC22A3 | 17671186 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000521626 | SLC22A3 | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000298BA3 | SLC22A3 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000E1E9E | SLC22A3 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008B558 | SLC22A3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000101787 | SLC22A3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000183BED | SLC22A3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC864 | SLC22A3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | SLC22A3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | SLC22A3 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | SLC22A3 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |