Gene Information gene info

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GENE：ATRX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATRX
FullNmae ATRX chromatin remodeler
LocusType gene with protein product
Status Approved
HGNC_id HGNC:886
EnsembleID ENSG00000085224
Uniprot P46100

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATRX pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATRX parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATRX mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATRX immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATRX GO:0000212,GO:0000228,GO:0000779,GO:0000781,GO:0000792,GO:0003682,GO:0004386,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005654,GO:0005721,GO:0005721,GO:0006281,GO:0006306,GO:0006325,GO:0006334,GO:0006338,GO:0006338,GO:0006338,GO:0006355,GO:0006366,GO:0007283,GO:0010571,GO:0015616,GO:0016604,GO:0016605,GO:0016887,GO:0030330,GO:0030900,GO:0031297,GO:0031297,GO:0031490,GO:0031509,GO:0032206,GO:0035064,GO:0035064,GO:0035128,GO:0035264,GO:0042393,GO:0045944,GO:0046872,GO:0060009,GO:0070087,GO:0070192,GO:0070198,GO:0072520,GO:0072711,GO:0099115,GO:0140658,GO:1904908

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATRX hsa:546 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NEK1 ATRX 14690447 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 ATRX 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 ATRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ATRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ATRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ATRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ATRX 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 ATRX 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS000009262D ATRX 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS0000148B91 ATRX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 ATRX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC ATRX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA ATRX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171525 ATRX 23708087 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000008DA94 ATRX 23708087 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000075D860 ATRX 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS00003B6B84 ATRX 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DAXX ATRX 25361965 interaction type N/A PTMCode2
ATRX DAXX 25361965 interaction type N/A PTMCode2
ATRX MECP2 25361965 interaction type N/A PTMCode2
MECP2 ATRX 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MFAP1 ATRX 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SNW1 ATRX 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DAXX ATRX 12953102 14990586 15252119 20147399 22102817 23135716 23222847 23329831 24234451 24651726 25348397 26496610 27898060 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,molecular sieving,physical interaction,imaging technique,in vitro ComPPI,IntAct,OmniPath
ZBED1 ATRX 22021382 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PCNA ATRX 24234451 24651726 25348397 colocalization fluorescence microscopy ComPPI,IntAct
CALM1 ATRX 25348397 N/A physical interaction ComPPI
BMI1 ATRX 25348397 N/A physical interaction ComPPI
ZNF512B ATRX 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H4C1 ATRX 25348397 N/A physical interaction ComPPI
DDX20 ATRX 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EZH2 ATRX 24234451 25348397 25417162 27898060 9499421 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,in vitro ComPPI,IntAct,OmniPath
SETDB1 ATRX 25348397 N/A physical interaction ComPPI
PRKDC ATRX 25348397 N/A physical interaction ComPPI
HDAC4 ATRX 25348397 N/A two hybrid,physical interaction ComPPI
WRN ATRX 25348397 N/A physical interaction ComPPI
XRCC5 ATRX 25348397 N/A physical interaction ComPPI
RBM14 ATRX 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RPA1 ATRX 25348397 N/A physical interaction ComPPI
RAD9A ATRX 25348397 N/A physical interaction ComPPI
PTPN4 ATRX 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
XRCC6 ATRX 25348397 N/A physical interaction ComPPI
HNRNPL ATRX 25348397 N/A physical interaction ComPPI
RAD51 ATRX 10851248 12205100 15466868 19671661 23801766 25348397 27898060 9321665 N/A two hybrid,physical interaction,in vitro ComPPI,OmniPath
BLM ATRX 25348397 N/A physical interaction ComPPI
H2BC21 ATRX 25348397 N/A physical interaction ComPPI
TMPO ATRX 25348397 N/A physical interaction ComPPI
NSD1 ATRX 25348397 N/A physical interaction ComPPI
SUMO2 ATRX 25348397 N/A physical interaction ComPPI
MDM2 ATRX 25348397 N/A physical interaction ComPPI
SMC1A ATRX 20159591 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CBX5 ATRX 10699177 15882967 20110566 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
POLD1 ATRX 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
H3C15 ATRX 21666677 21666679 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SUPT16H ATRX 25348397 N/A physical interaction ComPPI
TRIM28 ATRX 25348397 N/A physical interaction ComPPI
RASSF1 ATRX 25348397 N/A physical interaction ComPPI
SMC3 ATRX 20159591 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NEK1 ATRX 14690447 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AURKA ATRX 25348397 N/A physical interaction ComPPI
CEP126 ATRX 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ATRX PTN 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ATRX CCSER2 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ATRX LUC7L2 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ATRX SVIL 25348397 N/A two hybrid,physical interaction ComPPI
ATRX EIF4A2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ATRX RAD50 24234451 24651726 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
ATRX MRE11 24234451 24651726 25348397 colocalization,association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
ATRX NBN 24234451 24651726 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ATRX SSRP1 25348397 N/A physical interaction ComPPI
ATRX TP53 25348397 N/A physical interaction ComPPI
ATRX H1-2 25348397 N/A physical interaction ComPPI
ATRX H2BC13 25348397 N/A physical interaction ComPPI
ATRX H2AC4 25348397 N/A physical interaction ComPPI
ATRX RAD1 25348397 N/A physical interaction ComPPI
ATRX PML 25348397 N/A physical interaction ComPPI
ATRX TMPO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATRX CNOT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATRX LRRK2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATRX MACROH2A1 24234451 25348397 25417162 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATRX ZNF274 25348397 N/A physical interaction ComPPI
ATRX WDR1 25348397 N/A physical interaction ComPPI
ATRX EAF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ATRX NAF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ATRX EIF2AK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ATRX AP3B1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ATRX H2AX 25348397 N/A physical interaction ComPPI
ATRX PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
H3C1 ATRX 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
H3-3A ATRX 20110566 20211137 20504901 20651253 24234451 24530302 25348397 25538301 27898060 physical association pull down,physical interaction ComPPI,IntAct,OmniPath
COX4I1 ATRX 24234451 30021884 physical association cross-linking study IntAct
HNRNPD ATRX 24234451 30021884 physical association cross-linking study IntAct
NOMO1 ATRX 24234451 30021884 physical association cross-linking study IntAct
RRBP1 ATRX 24234451 30021884 physical association cross-linking study IntAct
ATRX MECP2 17296936 20159591 27898060 N/A N/A OmniPath

Visualization










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