GENE：ARID1A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ARID1A |
| FullNmae | AT-rich interaction domain 1A |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11110 |
| EnsembleID | ENSG00000117713 |
| Uniprot | O14497 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ARID1A | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ARID1A | GO:0000785,GO:0000785,GO:0003677,GO:0003677,GO:0003713,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006337,GO:0006338,GO:0006338,GO:0006357,GO:0006357,GO:0007399,GO:0016514,GO:0016514,GO:0016514,GO:0016922,GO:0030071,GO:0030520,GO:0030521,GO:0031491,GO:0035060,GO:0042921,GO:0045582,GO:0045597,GO:0045663,GO:0045815,GO:0045893,GO:0045893,GO:0070316,GO:0071564,GO:0071564,GO:0071565,GO:0071565,GO:0071565,GO:0140092,GO:1902459,GO:2000045,GO:2000781,GO:2000819 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ARID1A | hsa:8289 | path:hsa03082 | ATP-dependent chromatin remodeling - Homo sapiens (human) |
| ARID1A | hsa:8289 | path:hsa04714 | Thermogenesis - Homo sapiens (human) |
| ARID1A | hsa:8289 | path:hsa05225 | Hepatocellular carcinoma - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ARID1A | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ARID1A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ARID1A | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ARID1A | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | ARID1A | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | ARID1A | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | ARID1A | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | ARID1A | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ARID1A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000170CF4 | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS0000122ED0 | ARID1A | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000070B1D | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001C3AC1 | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000DD591 | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000035CC3E | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000AA464 | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005651EE | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000005481D | ARID1A | 20371350 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00001597DC | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000000B1C9 | ARID1A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00004DA9DB | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000157F5 | ARID1A | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | ARID1A | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E92A8 | ARID1A | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003677B2 | ARID1A | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000001C659 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040828B | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000235862 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017CCCB | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000383DF4 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013D17D | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005E6F45 | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FF522 | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006DA05 | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | ARID1A | 20371350 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001EB3 | ARID1A | 24793973 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000153377 | ARID1A | 25416803 26909602 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS000006372A | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039607D | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000259AE4 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDCD1 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DEA91 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007340 | ARID1A | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043C1C3 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | ARID1A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122F23 | ARID1A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | ARID1A | 20371350 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | ARID1A | 20371350 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | ARID1A | 20371350 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | ARID1A | 20371350 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000015188E | ARID1A | 20371350 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CE0C6 | ARID1A | 20371350 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F7766 | ARID1A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B83FE | ARID1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000079D48 | ARID1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000210075 | ARID1A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005C1F22 | ARID1A | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | ARID1A | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDK2 | ARID1A | 22135298 | phosphorylation | N/A | PhosphoSite |
| SMARCA2 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | SMARCA2 | 25361965 | interaction type | N/A | PTMCode2 |
| HIC1 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | HIC1 | 25361965 | interaction type | N/A | PTMCode2 |
| SMARCC1 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | SMARCC1 | 25361965 | interaction type | N/A | PTMCode2 |
| SMARCB1 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | SMARCB1 | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | SMARCE1 | 25361965 | interaction type | N/A | PTMCode2 |
| SMARCE1 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | SMARCA4 | 25361965 | interaction type | N/A | PTMCode2 |
| SMARCA4 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | SMARCD1 | 25361965 | interaction type | N/A | PTMCode2 |
| SMARCD1 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| SMARCC2 | ARID1A | 25361965 | interaction type | N/A | PTMCode2 |
| ARID1A | SMARCC2 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TFAP4 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SNW1 | ARID1A | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SMARCE1 | ARID1A | 11780067 24234451 25348397 | association | coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CDC5L | ARID1A | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RARA | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SMARCC1 | ARID1A | 24234451 24421395 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RARB | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| TP53BP1 | ARID1A | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| SKP1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| NFATC1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| JUN | ARID1A | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| AR | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SMAD2 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SMARCD1 | ARID1A | 11780067 24234451 25348397 | association | coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NCOA1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SMAD3 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| GATA1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| CUL3 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SMARCA4 | ARID1A | 11780067 11988099 12200431 12368262 15985610 23540691 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| ING1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| ARID1B | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| NFATC2 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| ECT2 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SMARCB1 | ARID1A | 24234451 25348397 30108113 | association | pull down,physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| CUL2 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| CUL1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SOX2 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| YAP1 | ARID1A | 24234451 24255178 25348397 | colocalization | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| ACTL6A | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| ITCH | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| MDC1 | ARID1A | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| EED | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| KLF1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| HIF1AN | ARID1A | 24234451 25348397 29426014 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| NR3C1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| PDCD6 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| NEDD4 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SS18 | ARID1A | 23540691 24234451 25348397 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CARM1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| ESR1 | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| BRCA1 | ARID1A | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| PGR | ARID1A | 25348397 | N/A | physical interaction | ComPPI |
| SMARCD3 | ARID1A | 18765789 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| SMARCC2 | ARID1A | 11780067 24234451 25348397 | association | coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| SMARCD2 | ARID1A | 24234451 25348397 30021884 | physical association | cross-linking study,physical interaction | ComPPI,IntAct |
| ARID1A | MLLT1 | 12665591 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| ARID1A | SMARCA2 | 11318604 12200431 14559996 16940996 22939629 24234451 25348397 26344197 27898060 8895581 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct,OmniPath |
| ARID1A | PBRM1 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | BCL7C | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | HIC1 | 19486893 24234451 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,physical interaction | ComPPI,IntAct |
| ARID1A | ADNP | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | CHD7 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | SIRT7 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | PHF10 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | DPF2 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | UNK | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | BCL7A | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | BCL7B | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | RARG | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | EYA2 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | TOP2A | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
| ARID1A | BCL6 | 16147992 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| ECH1 | ARID1A | 24234451 25348397 29426014 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |