Gene Information gene info

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GENE：GSTT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GSTT1
FullNmae glutathione S-transferase theta 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4641
EnsembleID ENSG00000277656
Uniprot P30711

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GSTT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GSTT1 GO:0004364,GO:0004364,GO:0004602,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0006749,GO:0006749,GO:0070062,GO:0098869

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GSTT1 hsa:2952 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa05200 Pathways in cancer - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa05204 Chemical carcinogenesis - DNA adducts - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
GSTT1 hsa:2952 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 GSTT1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GSTT1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
FKBP1A GSTT1 25348397 N/A physical interaction ComPPI
HBA1 GSTT1 25348397 N/A physical interaction ComPPI
ACTN2 GSTT1 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
EGFR GSTT1 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SIRT2 GSTT1 25348397 N/A physical interaction ComPPI
MID1 GSTT1 25348397 N/A physical interaction ComPPI
ATOX1 GSTT1 25348397 N/A physical interaction ComPPI
CSTB GSTT1 25348397 N/A physical interaction ComPPI
HBB GSTT1 25348397 N/A physical interaction ComPPI
HINT1 GSTT1 25348397 N/A physical interaction ComPPI
MYLK2 GSTT1 25348397 N/A physical interaction ComPPI
CHD4 GSTT1 24234451 30021884 physical association cross-linking study IntAct

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