Gene Information gene info

  1. Home

GENE：NOTCH1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NOTCH1
FullNmae notch receptor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7881
EnsembleID ENSG00000148400
Uniprot P46531

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NOTCH1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NOTCH1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NOTCH1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NOTCH1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NOTCH1 anoikis 25048699 Here we show that constitutive expression of Notch1 intracellular domain impairs secretory function of mouse prostate luminal cells, suppresses anoikis of luminal epithelial cells by augmenting NF-κB activity independent of Hes1. retulator signature

Go Annotation:

GeneSymbol Go id
NOTCH1 GO:0000122,GO:0000122,GO:0000139,GO:0001554,GO:0001669,GO:0001701,GO:0001837,GO:0001837,GO:0001889,GO:0001947,GO:0002040,GO:0002052,GO:0002085,GO:0002193,GO:0002437,GO:0003151,GO:0003157,GO:0003160,GO:0003162,GO:0003169,GO:0003180,GO:0003180,GO:0003180,GO:0003181,GO:0003182,GO:0003184,GO:0003184,GO:0003192,GO:0003198,GO:0003203,GO:0003207,GO:0003208,GO:0003209,GO:0003213,GO:0003214,GO:0003219,GO:0003222,GO:0003241,GO:0003252,GO:0003270,GO:0003273,GO:0003332,GO:0003344,GO:0003713,GO:0003713,GO:0004857,GO:0004888,GO:0005112,GO:0005509,GO:0005515,GO:0005576,GO:0005634,GO:0005634,GO:0005654,GO:0005789,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005912,GO:0006355,GO:0006357,GO:0006366,GO:0006606,GO:0006955,GO:0006959,GO:0007219,GO:0007219,GO:0007219,GO:0007219,GO:0007221,GO:0007283,GO:0007368,GO:0007386,GO:0007411,GO:0007440,GO:0007492,GO:0007507,GO:0008284,GO:0008284,GO:0008285,GO:0009912,GO:0009957,GO:0009986,GO:0010614,GO:0010628,GO:0010629,GO:0010812,GO:0010832,GO:0014031,GO:0014807,GO:0016324,GO:0017156,GO:0019899,GO:0021515,GO:0021915,GO:0030163,GO:0030216,GO:0030279,GO:0030324,GO:0030335,GO:0030513,GO:0030514,GO:0030900,GO:0031069,GO:0031100,GO:0031490,GO:0032495,GO:0032496,GO:0032966,GO:0035116,GO:0035148,GO:0035914,GO:0035924,GO:0042246,GO:0042670,GO:0042802,GO:0043086,GO:0043235,GO:0043235,GO:0045070,GO:0045603,GO:0045608,GO:0045618,GO:0045662,GO:0045668,GO:0045747,GO:0045892,GO:0045893,GO:0045944,GO:0045944,GO:0045955,GO:0046427,GO:0046533,GO:0046579,GO:0048103,GO:0048708,GO:0048709,GO:0048711,GO:0048715,GO:0048754,GO:0048873,GO:0050673,GO:0050679,GO:0050680,GO:0050768,GO:0055008,GO:0060038,GO:0060045,GO:0060253,GO:0060271,GO:0060317,GO:0060354,GO:0060379,GO:0060411,GO:0060412,GO:0060528,GO:0060740,GO:0060768,GO:0060842,GO:0060843,GO:0060948,GO:0060956,GO:0060979,GO:0060982,GO:0061101,GO:0061314,GO:0061384,GO:0062043,GO:0070168,GO:0070374,GO:0070986,GO:0071228,GO:0071372,GO:0071456,GO:0072017,GO:0072044,GO:0072091,GO:0072144,GO:0072148,GO:0072538,GO:0090051,GO:0090090,GO:0097150,GO:0097400,GO:0120163,GO:0140537,GO:1901201,GO:1902263,GO:1902339,GO:1903849,GO:2000048,GO:2000737,GO:2000811,GO:2000974,GO:2001027

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NOTCH1 hsa:4851 path:hsa01522 Endocrine resistance - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa05020 Prion disease - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa05200 Pathways in cancer - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
NOTCH1 hsa:4851 path:hsa05224 Breast cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NOTCH1 DLL1 20351093 21985982 22363487 26192618 interaction type,stimulation,association N/A ACSN,SignaLink
NOTCH1 JAG1 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 22390640 23343194 24023259 25730849 26192618 7542250 8666229 interaction type,stimulation N/A ACSN,SignaLink
NOTCH1 NUMB 11955436 11967263 12051714 15001769 16039586 17143292 17936032 19567869 19619488 20351093 20705860 20940030 21841793 22330899 22363130 22363487 23343194 24023259 25730849 26192618 7542250 8666229 association N/A ACSN
PSEN1 NOTCH1 10077672 10206645 12374741 15246694 18988627 22330899 22363130 23331499 26192618 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
ADAM10 NOTCH1 18676862 19601831 19704010 19726682 22006996 26192618 interaction type N/A ACSN
ADAM17 NOTCH1 10882063 18676862 18988627 19601831 19704010 19726682 22006996 23331499 26192618 9620803 interaction type N/A ACSN,SignaLink,SignaLink
GZMB NOTCH1 16798735 23180781 protein cleavage protease assay InnateDB
NOTCH1 CHUK 18560356 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
IKBKB NOTCH1 18560356 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG NOTCH1 18560356 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOTCH1 ABCC1 23180781 24782036 physical association anti tag coimmunoprecipitation InnateDB
KLF4 NOTCH1 23180781 25644173 physical association anti tag coimmunoprecipitation InnateDB
NOTCH1 NOTCH1 11591772 16256737 16847353 16990763 18722525 19165418 26467481 up-regulates activity,up-regulates quantity by expression,transcriptional regulation,relocalization reaction N/A Signor
SMAD3 NOTCH1 14638857 18988627 23331499 stimulation N/A SignaLink,SignaLink
NOTCH1 SMAD3 14638857 21071413 23331499 interaction type N/A SignaLink,SignaLink
NOTCH1 RBPJ 10637481 16530044 18988627 19800882 21071413 23331499 8749394 9032325 9111040 stimulation N/A SignaLink,SignaLink
JAG1 NOTCH1 10958687 11006133 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
JAG2 NOTCH1 10958687 11006133 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
DLL3 NOTCH1 10958687 23331499 stimulation N/A SignaLink,SignaLink
DTX1 NOTCH1 11153911 11226752 11564735 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
NOTCH1 LEF1 11604490 18988627 23331499 stimulation N/A SignaLink,SignaLink
DLL4 NOTCH1 10837024 11739188 18988627 23331499 stimulation N/A SignaLink,SignaLink
PSEN2 NOTCH1 15246694 23331499 stimulation N/A SignaLink,SignaLink
NOTCH3 NOTCH1 10433920 11404076 21071413 23331499 interaction type N/A SignaLink,SignaLink
LFNG NOTCH1 10934472 10935626 12486116 18988627 23331499 interaction type N/A SignaLink,SignaLink
DNER NOTCH1 15965470 23331499 stimulation N/A SignaLink,SignaLink
MFAP5 NOTCH1 16492672 23331499 stimulation N/A SignaLink,SignaLink
NOTCH1 MEF2C 10082551 18988627 23331499 stimulation N/A SignaLink,SignaLink
DAB1 NOTCH1 18593473 23331499 stimulation N/A SignaLink,SignaLink
NOTCH1 HIF1A 18722525 23331499 stimulation N/A SignaLink,SignaLink
LTC4S NOTCH1 11390662 23331499 stimulation N/A SignaLink
FBXW7 NOTCH1 11425854 11585921 17646408 23331499 stimulation N/A SignaLink
MAML2 NOTCH1 12370315 23331499 stimulation N/A SignaLink
MAML3 NOTCH1 12370315 23331499 stimulation N/A SignaLink
ITCH NOTCH1 10940313 12682059 23331499 stimulation N/A SignaLink
CNTN1 NOTCH1 14567914 23331499 stimulation N/A SignaLink
CNTN6 NOTCH1 15082708 23331499 stimulation N/A SignaLink
CCN3 NOTCH1 12050162 23331499 stimulation N/A SignaLink
MFAP2 NOTCH1 16492672 23331499 stimulation N/A SignaLink
NOTCH1 MTOR 19265851 23331499 stimulation N/A SignaLink
NOTCH1 SMAD1 14597575 23331499 stimulation N/A SignaLink
NOTCH1 RRAS 17664272 23331499 stimulation N/A SignaLink
CDK8 NOTCH1 15546612 23331499 stimulation N/A SignaLink
NOTCH1 SNW1 10713164 11404076 23331499 stimulation N/A SignaLink
LCK NOTCH1 14583609 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CNTN1 NOTCH1 20005715 interaction type N/A PSP
DTX1 NOTCH1 20005715 interaction type N/A PSP,SignaLink
JAG2 NOTCH1 20005715 interaction type N/A PSP
CNTN1 NOTCH1 20005715 N/A N/A SignaLink
JAG2 NOTCH1 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 NOTCH1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NOTCH1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NOTCH1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP73 NOTCH1 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NOTCH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
KLF5 NOTCH1 21868761 trascriptional regulation,stimulation inferred by curator TFlink
SIRT1 NOTCH1 23028940 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004AC389 NOTCH1 23034333 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002E92A8 NOTCH1 21285251 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000183BED NOTCH1 N/A 17150773 rna interference,inhibition experimental interaction detection miRSponge
URS0000330617 NOTCH1 N/A 17150773 rna interference,inhibition experimental interaction detection miRSponge
URS0000065D58 NOTCH1 17150773 rna interference,inhibition array technology,experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS00000A939F NOTCH1 19955368 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00000EED18 NOTCH1 14697198 17150773 19773441 20351093 22363487 22684561 23085450 23226240 \N rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS000027352D NOTCH1 22498974 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002C7B2B NOTCH1 22498974 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001F5B39 NOTCH1 21569010 rna interference,inhibition chromatin immunoprecipitation assay,miRNA interference luciferase reporter assay miRSponge
URS00000EED18 NOTCH1 14697198 17150773 18927107 19461653 19773441 20351093 22363487 22438124 22684561 23035210 23085450 23226240 23430952 25416803 26493107 28129650 28145431 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS0000330617 NOTCH1 17150773 23622248 25416803 mrna cleavage,inhibition experimental interaction detection,clash TarBase
URS0000183BED NOTCH1 17150773 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000065D58 NOTCH1 17150773 24029422 25311243 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000A939F NOTCH1 19955368 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00002E92A8 NOTCH1 21285251 21929751 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001F5B39 NOTCH1 21569010 23226395 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000027352D NOTCH1 22498974 23955600 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002C7B2B NOTCH1 22498974 23955600 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004AC389 NOTCH1 23034333 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00002152A8 NOTCH1 24029422 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000023BE29 NOTCH1 24885920 25416803 26299922 27738333 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000005CF5F NOTCH1 24029422 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001DE669 NOTCH1 24029422 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000012A1DD NOTCH1 23430952 23955600 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000171525 NOTCH1 23955600 25416803 26400206 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003E226A NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 NOTCH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F NOTCH1 25416803 26709677 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002233F4 NOTCH1 25416803 25998143 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS000033EBB8 NOTCH1 25416803 26742429 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001EFBE3 NOTCH1 25416803 26165719 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001C3AC1 NOTCH1 25416803 26500043 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 NOTCH1 22135298 phosphorylation N/A PhosphoSite
HIPK2 NOTCH1 22135298 phosphorylation N/A PhosphoSite
MAP3K1 NOTCH1 22135298 phosphorylation N/A PhosphoSite
YY1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 YY1 25361965 interaction type N/A PTMCode2
FURIN NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 FURIN 25361965 interaction type N/A PTMCode2
CBL NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 CBL 25361965 interaction type N/A PTMCode2
KAT2B NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 KAT2B 25361965 interaction type N/A PTMCode2
NOTCH1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 MAML1 25361965 interaction type N/A PTMCode2
MAML1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 NCSTN 25361965 interaction type N/A PTMCode2
NCSTN NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 REL 25361965 interaction type N/A PTMCode2
REL NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 ADAM17 25361965 interaction type N/A PTMCode2
ADAM17 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 DTX2 25361965 interaction type N/A PTMCode2
DTX2 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 GSK3B 25361965 interaction type N/A PTMCode2
GSK3B NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 CNTN1 25361965 interaction type N/A PTMCode2
CNTN1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 JAG2 25361965 interaction type N/A PTMCode2
JAG2 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 RBPJ 25361965 interaction type N/A PTMCode2
RBPJ NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 NUMB 25361965 interaction type N/A PTMCode2
NUMB NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 DLL1 25361965 interaction type N/A PTMCode2
DLL1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 ITCH 25361965 interaction type N/A PTMCode2
ITCH NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 POFUT1 25361965 interaction type N/A PTMCode2
POFUT1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 MEF2C 25361965 interaction type N/A PTMCode2
MEF2C NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 MAML2 25361965 interaction type N/A PTMCode2
MAML2 NOTCH1 25361965 interaction type N/A PTMCode2
JAG1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 JAG1 25361965 interaction type N/A PTMCode2
LFNG NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 LFNG 25361965 interaction type N/A PTMCode2
NFKB1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 NFKB1 25361965 interaction type N/A PTMCode2
NOTCH3 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 NOTCH3 25361965 interaction type N/A PTMCode2
DTX1 NOTCH1 25361965 interaction type N/A PTMCode2
NOTCH1 DTX1 25361965 interaction type N/A PTMCode2
NOTCH1 NOTCH1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 NOTCH1 19151708 24234451 25348397 physical association anti bait coimmunoprecipitation,far western blotting,pull down ComPPI,IntAct
GOLGA2 NOTCH1 25348397 N/A physical interaction ComPPI
SNW1 NOTCH1 10713164 14525934 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
GATAD2B NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RNF40 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DHX15 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PPP2R1A NOTCH1 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SMARCC1 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAGEA1 NOTCH1 25348397 N/A physical interaction ComPPI
ZBED4 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MCM5 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
VPS11 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
XIAP NOTCH1 14525934 17318174 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RING1 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM32 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ROCK1 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SNAI1 NOTCH1 25348397 N/A physical interaction ComPPI
DDX17 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TLE3 NOTCH1 25348397 N/A physical interaction ComPPI
CBL NOTCH1 11777909 14525934 25348397 26052821 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
VAV1 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK1 NOTCH1 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
REL NOTCH1 14525934 16319921 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
LCK NOTCH1 14525934 14583609 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HCLS1 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DLL4 NOTCH1 10837024 11739188 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAML1 NOTCH1 11101851 12644465 14525934 16530044 18427106 19907488 20972443 22325781 23022380 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
FBXW7 NOTCH1 11425854 11585921 14525934 17909182 20823234 23022380 24234451 25344755 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CCN3 NOTCH1 12050162 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NOTCH1 RBP3 11511084 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
NOTCH1 YY1 12913000 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 PIK3CG 14525934 14583609 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NOTCH1 KAT2A 10747963 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NOTCH1 JAG2 11006133 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 LFNG 10935626 12486116 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NOTCH1 MFNG 10935626 12486116 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NOTCH1 DTX1 11226752 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NOTCH1 SMAD3 14525934 14638857 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 ADAM17 10882063 14525934 25348397 9620803 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NOTCH1 NUMB 12682059 14525934 25348397 8755477 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 GSK3B 12123574 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 DLL1 11006133 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 KAT2B 10747963 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NOTCH1 CNTN1 14525934 14567914 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 ITCH 12682059 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 MAML2 12370315 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NOTCH1 MAML3 12370315 14525934 23022380 24234451 25348397 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
NOTCH1 DTX2 11226752 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
NOTCH1 WDR12 11827460 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NOTCH1 GFI1B 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
NOTCH1 APBA1 14525934 14756819 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
NOTCH1 MEF2C 10082551 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
NOTCH1 PSEN2 11518718 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NOTCH1 BLOC1S1 25348397 N/A in vivo ComPPI
NOTCH1 EP300 11604511 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NOTCH1 NUMBL 14525934 25348397 9169836 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
NOTCH1 POFUT1 12697902 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NOTCH1 XRCC6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NOTCH1 FURIN 14525934 25348397 9653148 N/A experimental interaction detection,in vitro ComPPI,HPRD
NOTCH1 RBPJ 10637481 10713164 14525934 16530044 17284587 21475249 23022380 24234451 25348397 25609649 26496610 8749394 9111040 association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro,in vivo,tandem affinity purification,surface plasmon resonance array,mass spectrometry study of hydrogen/deuterium exchange,two hybrid ComPPI,HPRD,IntAct
NOTCH1 PSEN1 10077672 10206645 12374741 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NOTCH1 NFKB1 11418662 14525934 16319921 24234451 25348397 8642313 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
NOTCH1 RELA 14525934 25348397 8642313 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NOTCH1 PIK3CA 25348397 N/A physical interaction ComPPI
NOTCH1 JAG1 11006133 14525934 18660822 23086448 24234451 25348397 colocalization experimental interaction detection,nuclear magnetic resonance,pull down,surface plasmon resonance,physical interaction,enzyme linked immunosorbent assay,confocal microscopy,surface plasmon resonance array ComPPI,HPRD,IntAct
NOTCH1 LEF1 11604490 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NOTCH1 AKT1 25348397 N/A physical interaction ComPPI
NOTCH1 CTNNB1 25348397 N/A physical interaction ComPPI
NOTCH1 CACNA1A 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NOTCH1 MDM2 25348397 N/A physical interaction ComPPI
NOTCH1 RUNX3 25348397 N/A physical interaction ComPPI
NOTCH1 KAT5 25348397 N/A physical interaction ComPPI
NOTCH1 APP 25348397 N/A physical interaction ComPPI
NOTCH1 APBB1 25348397 N/A physical interaction ComPPI
NOTCH1 EIF3F 25348397 N/A physical interaction ComPPI
NOTCH1 EPN1 25348397 N/A physical interaction ComPPI
NOTCH1 ILK 25348397 N/A physical interaction ComPPI
NOTCH1 NOTCH2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 NOTCH3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PRKAA1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 LIMK2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 TAB1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 MOB1A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RANBP9 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RANBP10 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ARHGEF2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 USP7 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 USP11 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 USP15 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PPP2CA 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PPP2R2A 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PPP6R1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PPP6R3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ARIH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ANAPC7 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ANAPC1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CDC23 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CDC27 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ANAPC5 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 STK38 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 GPS1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CAND1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SLFN5 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SLFN11 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CARMIL2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 LRCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 WDR11 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 NCKAP1L 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ARMC8 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RMC1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PTBP3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CCZ1B 25348397 N/A physical interaction,tandem affinity purification ComPPI
NOTCH1 SMARCA4 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PBRM1 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SMARCC2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 HLTF 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SMARCA5 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SMC1A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SMC3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PDS5A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 MAU2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SMCHD1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 TRIM28 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 WIZ 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RB1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PHF8 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CHD4 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RBBP4 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 HDAC1 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 KDM1A 23022380 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RNF2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 FRYL 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 HCFC1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ASCC3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SRRT 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 WWTR1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 HTATSF1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 MED23 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 MED25 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 BCL11B 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 IKZF1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 IKZF2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 IKZF3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 TCF12 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RUNX1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SMAD9 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 ZBTB2 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RFX1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 IFI16 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PRKDC 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PARP1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 TOP2B 23022380 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 MCM3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RFC1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RFC4 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 MMS19 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 RIF1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PRPF6 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PRPF8 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PRPF19 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 DHX8 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 SART1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PTBP1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CNOT1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 XPO5 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 NBEA 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 LRBA 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 MDN1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 TNPO1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 KPNB1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 IPO5 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 TRAPPC9 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 TRAPPC10 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CCT3 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CCT6A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 CCT8 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 VPS39 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 KIF3A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 KIF2A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 PPP2CB 25348397 N/A physical interaction ComPPI
NOTCH1 CAMK4 25348397 N/A physical interaction ComPPI
NOTCH1 ARRB1 25348397 N/A physical interaction ComPPI
NOTCH1 EGFL7 19503073 25348397 27898060 N/A physical interaction ComPPI,OmniPath
NOTCH1 LATS2 25348397 N/A physical interaction ComPPI
NOTCH1 WWP1 16785210 25348397 27898060 N/A physical interaction ComPPI,OmniPath
NOTCH1 TGFBR1 25348397 N/A physical interaction ComPPI
NOTCH1 USP12 25348397 N/A physical interaction ComPPI
NOTCH1 ANKRD44 25348397 N/A physical interaction ComPPI
NOTCH1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NOTCH1 RND3 25348397 N/A physical interaction ComPPI
NOTCH1 PRKCD 25348397 N/A physical interaction ComPPI
NOTCH1 RAB5A 25348397 N/A physical interaction ComPPI
NOTCH1 RAB7A 25348397 N/A physical interaction ComPPI
NOTCH1 LAMP1 25348397 N/A physical interaction ComPPI
NOTCH1 HGS 25348397 N/A physical interaction ComPPI
NOTCH1 ZMIZ1 25348397 N/A physical interaction ComPPI
NOTCH1 MAP1LC3A 25348397 N/A physical interaction ComPPI
NOTCH1 SQSTM1 25348397 N/A physical interaction ComPPI
NOTCH1 MAP3K1 25348397 N/A physical interaction ComPPI
NOTCH1 CDH1 25348397 N/A physical interaction ComPPI
NOTCH1 CTDSPL 25348397 N/A physical interaction ComPPI
NOTCH1 DLK2 25348397 N/A physical interaction ComPPI
NOTCH1 FANCA 25348397 N/A physical interaction ComPPI
NOTCH1 FANCC 25348397 N/A physical interaction ComPPI
NOTCH1 FANCF 25348397 N/A physical interaction ComPPI
NOTCH1 FANCG 25348397 N/A physical interaction ComPPI
NOTCH1 TRIM25 25348397 N/A physical interaction ComPPI
NOTCH1 B3GALT4 25348397 N/A physical interaction ComPPI
NOTCH1 CEP57L1 25348397 N/A physical interaction ComPPI
NOTCH1 COL4A6 25348397 N/A physical interaction ComPPI
NOTCH1 EXT1 25348397 N/A physical interaction ComPPI
NOTCH1 FAM185A 25348397 N/A physical interaction ComPPI
NOTCH1 KIAA1191 25348397 N/A physical interaction ComPPI
NOTCH1 HMGN5 25348397 N/A physical interaction ComPPI
NOTCH1 MAGED1 25348397 N/A physical interaction ComPPI
NOTCH1 GOPC 25348397 N/A physical interaction ComPPI
NOTCH1 POU2AF1 25348397 N/A physical interaction ComPPI
NOTCH1 DAZAP2 25348397 N/A physical interaction ComPPI
NOTCH1 KCTD10 25348397 N/A physical interaction ComPPI
NOTCH1 CUL3 25348397 N/A physical interaction ComPPI
NOTCH1 DTX4 25348397 N/A physical interaction ComPPI
NOTCH1 ADAM10 25348397 N/A physical interaction ComPPI
NOTCH1 HIF1A 18427106 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NOTCH1 UBC 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
NOTCH1 UBA52 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
NOTCH1 ATM 24234451 25348397 25895060 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
NOTCH1 HIF1AN 24234451 25348397 26752685 hydroxylation reaction hydroxylase assay ComPPI,IntAct
NOTCH1 LILRB2 24234451 25348397 25714926 27898060 physical association anti bait coimmunoprecipitation ComPPI,IntAct,OmniPath
RHOA NOTCH1 25348397 N/A physical interaction ComPPI
UBB NOTCH1 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
RPS27A NOTCH1 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
RBM10 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NEDD4L NOTCH1 25348397 N/A physical interaction ComPPI
TBL1XR1 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LNX2 NOTCH1 25348397 N/A physical interaction ComPPI
ERH NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ARL6IP5 NOTCH1 25348397 N/A physical interaction ComPPI
RTRAF NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ARIH2 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
WDR6 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NOTCH1 NOTCH1 10669757 11425854 11585921 14525934 N/A experimental interaction detection HPRD
BX42 NOTCH1 10713164 24234451 physical association two hybrid IntAct
NOTCH1 CCZ1 23022380 24234451 association tandem affinity purification IntAct
LCK NOTCH1 14583609 27898060 stimulant N/A OmniPath
NUMB NOTCH1 12682059 15358736 23252402 27898060 8755477 inhibition,stimulant N/A OmniPath
ITCH NOTCH1 10940313 12682059 1268206 27898060 inhibition,stimulant N/A OmniPath
NOTCH1 TCF3 27898060 9528794 inhibition N/A OmniPath
WNT1 NOTCH1 18495817 27898060 stimulant N/A OmniPath
NOTCH1 WNT1 18495817 27898060 stimulant N/A OmniPath
NOTCH1 BMP4 17537801 27898060 stimulant N/A OmniPath
CHUK NOTCH1 18560356 27898060 N/A N/A OmniPath
NOTCH1 CHUK 18560356 27898060 stimulant N/A OmniPath
SIAH1 NOTCH1 20940030 27898060 stimulant N/A OmniPath
NOTCH1 MYC 16847353 27898060 stimulant N/A OmniPath
MDM2 NOTCH1 22128911 23252402 27898060 stimulant N/A OmniPath
PIN1 NOTCH1 19151708 27898060 stimulant N/A OmniPath
FBXW7 NOTCH1 11425854 11461910 11585921 15546612 17526737 17646408 17646409 17909182 20571051 20823234 21820430 22388891 23022380 24085301 25344755 26033182 26108681 27898060 inhibition,stimulant N/A OmniPath
NOTCH1 SMAD1 14597575 27898060 stimulant N/A OmniPath
NOTCH1 NFKB1 11418662 11591772 16319921 27898060 8642313 stimulant N/A OmniPath
SIRT1 NOTCH1 22223095 27898060 inhibition N/A OmniPath
NOTCH1 PAX8 18495817 27898060 stimulant N/A OmniPath
NOTCH1 ATOH1 16283144 27898060 inhibition N/A OmniPath
GSK3A NOTCH1 19214430 27898060 inhibition N/A OmniPath
KAT5 NOTCH1 17368826 17636029 27898060 inhibition,stimulant N/A OmniPath
NOTCH1 SOX2 17537801 27898060 stimulant N/A OmniPath
NOTCH1 JAG2 11006133 15358736 27898060 inhibition N/A OmniPath
JAG2 NOTCH1 11006133 27898060 9315665 inhibition,stimulant N/A OmniPath
ADAM17 NOTCH1 10882063 27898060 9620803 stimulant N/A OmniPath
MAML1 NOTCH1 11101851 11390662 11997524 12370315 12644465 16530044 21820430 22100894 23022380 27898060 inhibition,stimulant N/A OmniPath
EIF3F NOTCH1 21124883 27898060 stimulant N/A OmniPath
NOTCH1 LEF1 11604490 27898060 stimulant N/A OmniPath
NOTCH1 FOXI2 18495817 27898060 inhibition N/A OmniPath
NOTCH1 RBPJ 10637481 10713164 11390662 11518718 11997524 12644465 16530044 17210915 17284587 17526737 17636029 19165418 19800882 19907488 21820430 22100894 22143792 22325781 23022380 23103515 25609649 26033182 26186194 26496610 27898060 8749394 9032325 9111040 stimulant N/A OmniPath
DLL1 NOTCH1 11006133 15358736 16140393 17537801 27898060 stimulant N/A OmniPath
NOTCH1 DLL1 11006133 15358736 17537801 27898060 inhibition N/A OmniPath
RUNX3 NOTCH1 19800882 27898060 inhibition N/A OmniPath
MAPK8IP1 NOTCH1 20508646 27898060 inhibition N/A OmniPath
LFNG NOTCH1 10934472 10935626 12486116 27898060 inhibition,stimulant N/A OmniPath
NOTCH1 RRAS 17664272 27898060 stimulant N/A OmniPath
CSNK2A1 NOTCH1 21685388 24220241 27898060 N/A N/A OmniPath
NOTCH1 JAG1 11006133 16713569 17537801 18495817 18660822 20720151 21820430 23086448 27898060 stimulant N/A OmniPath
JAG1 NOTCH1 11006133 16713569 17537801 18495817 18660822 20720151 21820430 23086448 27898060 7697721 inhibition,stimulant N/A OmniPath
PSEN1 NOTCH1 10077672 10206645 10593990 12374741 15246694 27898060 stimulant N/A OmniPath
YY1 NOTCH1 12913000 27898060 inhibition N/A OmniPath
NOTCH1 HIF1A 16256737 18722525 27898060 stimulant N/A OmniPath
KAT2B NOTCH1 10747963 22120716 23029358 27898060 stimulant N/A OmniPath
NOTCH1 HES1 18495817 19165418 27898060 stimulant N/A OmniPath
NOTCH1 MTOR 19265851 27898060 stimulant N/A OmniPath
GSK3B NOTCH1 12123574 27898060 stimulant N/A OmniPath
NLK NOTCH1 20118921 27898060 inhibition N/A OmniPath
HIF1AN NOTCH1 18299578 26752685 27898060 inhibition N/A OmniPath
IKBKB NOTCH1 18560356 27898060 N/A N/A OmniPath
NOTCH1 SMAD3 14638857 27898060 N/A N/A OmniPath
SMAD3 NOTCH1 14638857 27898060 stimulant N/A OmniPath
RUNX2 NOTCH1 20740684 27898060 inhibition N/A OmniPath
NOTCH1 SNW1 10713164 11404076 1140408 15546612 27898060 stimulant N/A OmniPath
SNW1 NOTCH1 10713164 11404076 15546612 27898060 stimulant N/A OmniPath
DLL4 NOTCH1 10837024 11739188 16140393 27898060 stimulant N/A OmniPath
CSK NOTCH1 22479394 27898060 stimulant N/A OmniPath
NOTCH3 NOTCH1 1043392 11404076 27898060 N/A N/A OmniPath
CNTN1 NOTCH1 14567914 27898060 stimulant N/A OmniPath
MAML3 NOTCH1 12370315 23022380 27898060 stimulant N/A OmniPath
POFUT1 NOTCH1 12697902 12909620 27898060 stimulant N/A OmniPath
DLL3 NOTCH1 16140393 27898060 stimulant N/A OmniPath
KPNA3 NOTCH1 20454918 27898060 stimulant N/A OmniPath
DNER NOTCH1 15965470 27898060 stimulant N/A OmniPath
CDK8 NOTCH1 15546612 27898060 inhibition,stimulant N/A OmniPath
PSEN2 NOTCH1 11518718 15246694 27898060 stimulant N/A OmniPath
KPNA6 NOTCH1 20454918 27898060 stimulant N/A OmniPath
NOTCH1 HEY1 15207708 27898060 stimulant N/A OmniPath
MAML2 NOTCH1 12370315 27898060 stimulant N/A OmniPath
DYRK1A NOTCH1 19383720 27898060 inhibition N/A OmniPath
DTX1 NOTCH1 11153911 11226752 11564735 20208568 27898060 stimulant N/A OmniPath
DLK1 NOTCH1 21419176 27898060 inhibition N/A OmniPath
KPNA4 NOTCH1 20454918 27898060 stimulant N/A OmniPath
RFNG NOTCH1 12486116 27898060 stimulant N/A OmniPath
FURIN NOTCH1 22479394 27898060 9653148 stimulant N/A OmniPath
GXYLT1 NOTCH1 22117070 27898060 stimulant N/A OmniPath
MFNG NOTCH1 10935626 12486116 27898060 stimulant N/A OmniPath
XXYLT1 NOTCH1 22117070 27898060 stimulant N/A OmniPath
DAB1 NOTCH1 22394407 27898060 stimulant N/A OmniPath
HEY2 NOTCH1 16682003 27898060 inhibition N/A OmniPath
GXYLT2 NOTCH1 22117070 27898060 stimulant N/A OmniPath
CCNC NOTCH1 15546612 27898060 inhibition N/A OmniPath
CNTN6 NOTCH1 15082708 27898060 stimulant N/A OmniPath
DLK2 NOTCH1 21419176 27898060 inhibition N/A OmniPath
POGLUT1 NOTCH1 22872643 27898060 stimulant N/A OmniPath
MFAP2 NOTCH1 16492672 27898060 N/A N/A OmniPath
MFAP5 NOTCH1 16492672 27898060 inhibition N/A OmniPath

Visualization










  Return