GENE：GSTM2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GSTM2 |
| FullNmae | glutathione S-transferase mu 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4634 |
| EnsembleID | ENSG00000213366 |
| Uniprot | P28161 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GSTM2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GSTM2 | GO:0004364,GO:0004364,GO:0004602,GO:0005102,GO:0005504,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0006749,GO:0006749,GO:0010880,GO:0010881,GO:0014809,GO:0016529,GO:0018916,GO:0019899,GO:0042178,GO:0042803,GO:0043295,GO:0043651,GO:0045171,GO:0051122,GO:0055119,GO:0060315,GO:0060316,GO:0070062,GO:0070458,GO:0071313,GO:0098869 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| GSTM2 | hsa:2946 | path:hsa00480 | Glutathione metabolism - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa00980 | Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa00982 | Drug metabolism - cytochrome P450 - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa00983 | Drug metabolism - other enzymes - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa01524 | Platinum drug resistance - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa05200 | Pathways in cancer - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa05204 | Chemical carcinogenesis - DNA adducts - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa05207 | Chemical carcinogenesis - receptor activation - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa05208 | Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa05225 | Hepatocellular carcinoma - Homo sapiens (human) |
| GSTM2 | hsa:2946 | path:hsa05418 | Fluid shear stress and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CTCF | GSTM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GSTM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | GSTM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | GSTM2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | GSTM2 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |