Gene Information gene info

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GENE：ISYNA1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ISYNA1
FullNmae inositol-3-phosphate synthase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29821
EnsembleID ENSG00000105655
Uniprot Q9NPH2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ISYNA1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ISYNA1 GO:0004512,GO:0004512,GO:0004512,GO:0005515,GO:0005737,GO:0005829,GO:0006021,GO:0006021,GO:0006021,GO:0008654

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ISYNA1 hsa:51477 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
ISYNA1 hsa:51477 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 ISYNA1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ISYNA1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 ISYNA1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ISYNA1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ISYNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ISYNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ISYNA1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ISYNA1 15464731 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F4AC3 ISYNA1 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS00003CF1AD ISYNA1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 ISYNA1 24234451 25348397 29568061 association pull down ComPPI,IntAct
PPIB ISYNA1 25348397 N/A physical interaction ComPPI
GLRX3 ISYNA1 25348397 N/A physical interaction ComPPI
VCP ISYNA1 25348397 N/A physical interaction ComPPI
HNRNPH2 ISYNA1 25348397 N/A physical interaction ComPPI
ARHGDIA ISYNA1 25348397 N/A physical interaction ComPPI
DLD ISYNA1 25348397 N/A physical interaction ComPPI
PGD ISYNA1 25348397 N/A physical interaction ComPPI
NTRK1 ISYNA1 25348397 N/A physical interaction ComPPI
CDH1 ISYNA1 25348397 N/A physical interaction ComPPI
PPP2CA ISYNA1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RDX ISYNA1 25348397 N/A physical interaction ComPPI
ABCE1 ISYNA1 25348397 N/A physical interaction ComPPI
SUMO3 ISYNA1 25348397 N/A physical interaction ComPPI
CYB5A ISYNA1 25348397 N/A physical interaction ComPPI
DUSP14 ISYNA1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TPD52L1 ISYNA1 25348397 N/A physical interaction ComPPI
MSN ISYNA1 25348397 N/A physical interaction ComPPI
TRAF4 ISYNA1 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
ACE2 ISYNA1 25348397 N/A physical interaction ComPPI
ALDOC ISYNA1 25348397 N/A physical interaction ComPPI
PREP ISYNA1 25348397 N/A physical interaction ComPPI
TRIM25 ISYNA1 25348397 N/A physical interaction ComPPI
POT1 ISYNA1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
EEF2 ISYNA1 25348397 N/A physical interaction ComPPI
UCHL3 ISYNA1 25348397 N/A physical interaction ComPPI
FBXW11 ISYNA1 25348397 N/A physical interaction ComPPI
IKBKE ISYNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EZR ISYNA1 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ECHS1 ISYNA1 25348397 N/A physical interaction ComPPI
NME2 ISYNA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
USE1 ISYNA1 19369418 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ALDOA ISYNA1 25348397 N/A physical interaction ComPPI
ISYNA1 PLS1 25348397 N/A physical interaction ComPPI

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