Gene Information gene info

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GENE：SH3GL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SH3GL2
FullNmae SH3 domain containing GRB2 like 2, endophilin A1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10831
EnsembleID ENSG00000107295
Uniprot Q99962

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SH3GL2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SH3GL2 lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SH3GL2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SH3GL2 GO:0000139,GO:0001933,GO:0005515,GO:0005737,GO:0005769,GO:0005829,GO:0005886,GO:0007165,GO:0007417,GO:0008289,GO:0010629,GO:0016191,GO:0030669,GO:0031175,GO:0042802,GO:0042995,GO:0048471,GO:0097484,GO:0098793,GO:0098978,GO:1905604,GO:1990416

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SH3GL2 hsa:6456 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ITCH SH3GL2 17038327 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
IL6 SH3GL2 16169070 23180781 physical association two hybrid InnateDB
APP SH3GL2 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
SH3GL2 CBL 20005715 interaction type N/A PSP,SignaLink
SH3GL2 DNM2 20005715 interaction type N/A PSP
SH3GL2 PAK2 20005715 interaction type N/A PSP
SH3GL2 PAK2 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
YBX1 SH3GL2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA SH3GL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SH3GL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SH3GL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 SH3GL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SH3GL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000007A060 SH3GL2 23029364 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000007A060 SH3GL2 23029364 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000003ABC4 SH3GL2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000008F0CF SH3GL2 25416803 27038654 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
ROCK2 SH3GL2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
LCP2 SH3GL2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3KBP1 SH3GL2 11894095 11894096 12218189 14525934 16164598 21900206 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PAK2 SH3GL2 14525934 16374509 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GSTM3 SH3GL2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ACTG1 SH3GL2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EMD SH3GL2 14525934 16169070 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CALM1 SH3GL2 25348397 N/A physical interaction ComPPI
DPPA4 SH3GL2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DPYSL4 SH3GL2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 AMPH 14525934 25348397 9315708 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SH3GL2 BIN1 14525934 25348397 9315708 N/A experimental interaction detection,in vitro ComPPI,HPRD
SH3GL2 DNM1 11877424 14525934 15834155 24234451 25348397 9238017 N/A experimental interaction detection,surface plasmon resonance,physical interaction,in vitro,surface plasmon resonance array ComPPI,HPRD,IntAct
SH3GL2 MAP4K3 11384986 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SH3GL2 ADAM15 10531379 14525934 16374509 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
SH3GL2 PDCD6IP 12034747 14525934 17350572 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SH3GL2 ITCH 14525934 14684745 17038327 24234451 25348397 26613292 27898060 ubiquitination reaction,colocalization,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
SH3GL2 SYNJ1 10542231 11292345 12456676 14525934 18093523 20064468 24234451 25348397 27898060 9238017 9341169 N/A two hybrid,experimental interaction detection,phage display,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
SH3GL2 SH3GL3 14525934 16115810 21900206 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SH3GL2 ADRB1 10535961 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SH3GL2 ATXN2 14525934 16115810 16713569 18602463 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
SH3GL2 SLC17A7 14525934 16606361 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
SH3GL2 IL6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SH3GL2 EGFL6 14525934 16169070 21900206 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SH3GL2 HLA-DQA1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SH3GL2 TCEA2 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SH3GL2 ADAM19 25348397 N/A physical interaction ComPPI
SH3GL2 ADAM9 10531379 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
SH3GL2 CBL 11894095 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SH3GL2 EGFR 11894095 24234451 24658140 25348397 physical association anti bait coimmunoprecipitation,ubiquitin reconstruction,physical interaction ComPPI,IntAct
SH3GL2 ZXDC 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 PPP1R21 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 DLGAP4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 F13A1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 ZNF219 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 TIAM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 SH3GL1 16115810 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 ZNF580 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 DACT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 GCH1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 PRR14 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 TMEM108 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 TYMS 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 MAST2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 PPP6R1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 CLEC3B 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 ITSN1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 DNM3 25348397 N/A physical interaction ComPPI
SH3GL2 CD2AP 25348397 N/A physical interaction ComPPI
SH3GL2 DYRK1A 25348397 N/A physical interaction ComPPI
SH3GL2 SYNM 25348397 N/A physical interaction ComPPI
SH3GL2 DNM2 15834155 16696976 17257598 24234451 25348397 physical association pull down,surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct
SH3GL2 TERF1 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
SH3GL2 LRRK2 22998870 24234451 25348397 25501810 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
SH3GL2 APP 25348397 N/A physical interaction ComPPI
SH3GL2 PAXIP1 21163940 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 IPO11 25348397 N/A physical interaction ComPPI
SH3GL2 ARNT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SH3GL2 AZU1 25348397 N/A physical interaction ComPPI
SH3GL2 TANGO2 25348397 N/A physical interaction ComPPI
SH3GL2 ARHGAP8 25348397 N/A physical interaction ComPPI
SH3GL2 FBXO32 25348397 N/A physical interaction ComPPI
SH3GL2 ADRB3 24234451 25348397 25517094 physical association pull down,physical interaction ComPPI,IntAct
SH3GL2 ADRA2A 24234451 25348397 25517094 physical association pull down,physical interaction ComPPI,IntAct
SH3GL2 ADRA2B 24234451 25348397 25517094 physical association pull down,physical interaction ComPPI,IntAct
SH3GL2 DRD3 25348397 N/A pull down,physical interaction ComPPI
SH3GL2 CHRM2 24234451 25348397 25517094 physical association pull down,physical interaction ComPPI,IntAct
SH3GL2 CHRM4 24234451 25348397 25517094 physical association pull down,physical interaction ComPPI,IntAct
SH3GL2 HRH1 24234451 25348397 25517094 physical association pull down,physical interaction ComPPI,IntAct
SH3GL2 HRH3 25348397 N/A pull down,physical interaction ComPPI
SH3GL2 RAPH1 24076656 24234451 25348397 25517094 colocalization,physical association far western blotting,protein array,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct
SH3GL2 ASAP1 16636290 24234451 25348397 N/A enzyme linked immunosorbent assay ComPPI,IntAct
SH3GL2 IGHM 21900206 24234451 25348397 physical association two hybrid ComPPI,IntAct
SH3GL2 SRGAP3 24234451 25348397 25819436 physical association anti tag coimmunoprecipitation ComPPI,IntAct
ERH SH3GL2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPN23 SH3GL2 17174262 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SH3GL2 SH3GL2 10531379 14525934 16115810 20404169 24234451 25517094 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,two hybrid HPRD,IntAct
WTAP SH3GL2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
ROCK2 SH3GL2 16164598 27898060 inhibition,stimulant N/A OmniPath
IL6 SH3GL2 16169070 27898060 N/A N/A OmniPath
LRRK2 SH3GL2 22998870 25501810 27898060 inhibition N/A OmniPath

Visualization










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