Gene Information gene info

GENE:CSTF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CSTF2
FullNmae cleavage stimulation factor subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2484
EnsembleID ENSG00000101811
Uniprot P33240

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CSTF2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CSTF2 GO:0003723,GO:0003723,GO:0003729,GO:0005515,GO:0005654,GO:0005654,GO:0005847,GO:0005847,GO:0016604,GO:0031124,GO:0071920,GO:1990090

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CSTF2 hsa:1478 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CSTF2 ELP1 16169070 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 CSTF2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 CSTF2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CSTF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 CSTF2 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C770D CSTF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000184017 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD CSTF2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075D860 CSTF2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000042935A CSTF2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001DA458 CSTF2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E728C CSTF2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 CSTF2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 CSTF2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005FDE70 CSTF2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE CSTF2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 CSTF2 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 CSTF2 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039607D CSTF2 20371350 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000003ABC4 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C CSTF2 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC73 CSTF2 19136632 24234451 25348397 association,physical association anti bait coimmunoprecipitation,cosedimentation through density gradient,physical interaction ComPPI,IntAct
CHMP2A CSTF2 25348397 N/A physical interaction ComPPI
CSTF2 CSTF3 10669729 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CSTF2 SUB1 11389848 14525934 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
CSTF2 DDX1 11598190 14525934 22939629 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
CSTF2 SYMPK 10669729 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CSTF2 KAT5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
CSTF2 BAG6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 IMMT 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 ELP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 ERG28 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 UBQLN1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
CSTF2 FEZ1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 EEF1G 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 CEP126 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CSTF2 ECH1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 BARD1 10477523 20379136 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
CSTF2 BRCA1 10477523 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF2 CHD3 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CSTF2 CSTF1 25348397 N/A physical interaction ComPPI
CSTF2 CPSF1 25348397 N/A physical interaction ComPPI
CSTF2 CPSF2 18688255 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF2 SRRM1 25348397 N/A physical interaction ComPPI
CSTF2 POLR2A 25348397 N/A physical interaction ComPPI
CSTF2 APP 25348397 N/A physical interaction ComPPI
CSTF2 CPSF6 25348397 N/A physical interaction ComPPI
CSTF2 MAX 25348397 N/A physical interaction ComPPI
CSTF2 EIF4B 25348397 N/A physical interaction ComPPI
CSTF2 NUP153 25348397 N/A physical interaction ComPPI
CSTF2 DDB1 25348397 N/A physical interaction ComPPI
CSTF2 CPSF3 18688255 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF2 PARN 20379136 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF2 BABAM1 25348397 N/A physical interaction ComPPI
CSTF2 CDKN2A 25348397 N/A physical interaction ComPPI
CSTF2 CDKN2A 25348397 N/A physical interaction ComPPI
CSTF2 AKAP2 25348397 N/A physical interaction ComPPI
CSTF2 GET4 25348397 N/A physical interaction ComPPI
CSTF2 MAP4 25348397 N/A physical interaction ComPPI
CSTF2 LSM8 25348397 N/A physical interaction ComPPI
CSTF2 WWOX 25348397 N/A physical interaction ComPPI
CSTF2 RBBP6 25348397 N/A physical interaction ComPPI
CSTF2 HGS 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CSTF2 TFG 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CSTF2 SS18L1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CSTF2 SPAG8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CSTF2 ZNF341 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CSTF2 MOV10 25348397 N/A physical interaction ComPPI
CSTF2 CUL7 25348397 N/A physical interaction ComPPI
CSTF2 OBSL1 25348397 N/A physical interaction ComPPI
CSTF2 SLC25A41 25348397 N/A physical interaction ComPPI
CSTF2 TTC29 25348397 N/A physical interaction ComPPI
CSTF2 RP2 25348397 N/A physical interaction ComPPI
CSTF2 SLC30A4 25348397 N/A physical interaction ComPPI
CSTF2 AGER 25348397 N/A physical interaction ComPPI
CSTF2 CYP1A1 25348397 N/A physical interaction ComPPI
CSTF2 CD2AP 25348397 N/A physical interaction ComPPI
CSTF2 NONO 25348397 N/A physical interaction ComPPI
CSTF2 PABPC1 25348397 N/A physical interaction ComPPI
CSTF2 PAPOLA 25348397 N/A physical interaction ComPPI
CSTF2 PFDN6 25348397 N/A physical interaction ComPPI
CSTF2 XPO1 25348397 N/A physical interaction ComPPI
CSTF2 CSTF2T 25348397 N/A physical interaction ComPPI
CSTF2 KIAA1143 25348397 N/A physical interaction ComPPI
CSTF2 PCF11 25348397 N/A physical interaction ComPPI
CSTF2 SH3KBP1 25348397 N/A physical interaction ComPPI
CSTF2 TTC27 25348397 N/A physical interaction ComPPI
CSTF2 EWSR1 25348397 N/A physical interaction ComPPI
CSTF2 MKNK2 25348397 N/A physical interaction ComPPI
CSTF2 KIF21B 25348397 N/A physical interaction ComPPI
CSTF2 FIP1L1 25348397 N/A physical interaction ComPPI
CSTF2 SSU72 25348397 N/A physical interaction ComPPI
CSTF2 CPSF4 25348397 N/A physical interaction ComPPI
CSTF2 CPEB1 25348397 N/A physical interaction ComPPI
CSTF2 TUT1 18288197 21102410 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CSTF2 HDHD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 ATP23 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 STH 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 UFSP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 METTL27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 LINC01565 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 POU6F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 CNOT2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 CEACAM6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 PRDM6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 RFX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 AKAP8L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CSTF2 MDC1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
DDX19B CSTF2 25348397 N/A physical interaction ComPPI
KRT222 CSTF2 24234451 30021884 physical association cross-linking study IntAct
SMC1A CSTF2 24234451 30021884 physical association cross-linking study IntAct
SYMPK CSTF2 10669729 21896654 26496610 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008C0EDC CSTF2 27087310 direct interaction,inhibition N/A NPInter

Visualization