Gene Information gene info

GENE:EMP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EMP2
FullNmae epithelial membrane protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3334
EnsembleID ENSG00000213853
Uniprot P54851

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EMP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EMP2 autophagy 39866225 Conversely, overexpression of EMP2 enhances the invasive capacity of HCC cells and induces autophagy. retulator signature

Go Annotation:

GeneSymbol Go id
EMP2 GO:0000139,GO:0001765,GO:0001787,GO:0001913,GO:0001952,GO:0001954,GO:0003093,GO:0005178,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005794,GO:0005794,GO:0005829,GO:0005886,GO:0005886,GO:0006915,GO:0007015,GO:0007155,GO:0007155,GO:0007160,GO:0007566,GO:0008284,GO:0009986,GO:0010594,GO:0016020,GO:0016324,GO:0016477,GO:0019900,GO:0019901,GO:0019901,GO:0031410,GO:0032060,GO:0032147,GO:0034394,GO:0034394,GO:0043534,GO:0043549,GO:0044854,GO:0045022,GO:0045121,GO:0045177,GO:0045765,GO:0045765,GO:0045766,GO:0048471,GO:0060136,GO:0060914,GO:0062043,GO:0070252,GO:0072659,GO:1990266,GO:2001046,GO:2001046,GO:2001212

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EMP2 hsa:2013 path:hsa04510 Focal adhesion - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR EMP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 EMP2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 EMP2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C EMP2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EMP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000277201 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000237E04 EMP2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005C1F22 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000544FF1 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000054A671 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043F369 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006DA05 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 EMP2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 EMP2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 EMP2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 EMP2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 EMP2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EPM2AIP1 EMP2 25348397 N/A physical interaction ComPPI
EMP2 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization