Gene Information gene info

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GENE：FGF7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FGF7
FullNmae fibroblast growth factor 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3685
EnsembleID ENSG00000140285
Uniprot P21781

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FGF7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FGF7 GO:0001935,GO:0001938,GO:0005111,GO:0005515,GO:0005576,GO:0005615,GO:0005737,GO:0005794,GO:0007165,GO:0008083,GO:0008201,GO:0008284,GO:0008543,GO:0008543,GO:0008544,GO:0009611,GO:0009887,GO:0010463,GO:0010628,GO:0010838,GO:0030036,GO:0030154,GO:0030324,GO:0030334,GO:0031069,GO:0034394,GO:0042056,GO:0045893,GO:0050679,GO:0050679,GO:0050731,GO:0050731,GO:0050918,GO:0050918,GO:0051450,GO:0051549,GO:0051781,GO:0060445,GO:0060501,GO:0060665,GO:0061033,GO:2000288

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FGF7 hsa:2252 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
FGF7 hsa:2252 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
FGF7 hsa:2252 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
FGF7 hsa:2252 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
FGF7 hsa:2252 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
FGF7 hsa:2252 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
FGF7 hsa:2252 path:hsa05200 Pathways in cancer - Homo sapiens (human)
FGF7 hsa:2252 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
FGF7 hsa:2252 path:hsa05218 Melanoma - Homo sapiens (human)
FGF7 hsa:2252 path:hsa05224 Breast cancer - Homo sapiens (human)
FGF7 hsa:2252 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FGF7 FGFR2 21071413 23331499 8663044 9582367 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
AR FGF7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 FGF7 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 FGF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FGF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FGF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN FGF7 15840658 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 FGF7 9869450 trascriptional regulation,stimulation inferred by curator TFlink
RELA FGF7 9869450 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 FGF7 19177201 19701459 \N rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000338542 FGF7 18668040 19177201 19701459 23807165 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS0000171CD1 FGF7 21106054 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000042E1F FGF7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000B59A2 FGF7 22100165 22291592 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS000006A1CB FGF7 22100165 22291592 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 FGF7 22100165 22291592 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 FGF7 22100165 22291592 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C FGF7 22100165 22291592 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 FGF7 22100165 22291592 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 FGF7 22100165 22291592 23708386 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FGF7 HSPG2 25361965 interaction type N/A PTMCode2
HSPG2 FGF7 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FGFR2 FGF7 25348397 N/A affinity chromatography technology,cross-linking study,physical interaction,physical interaction,biochemical,in vivo ComPPI
DUSP3 FGF7 1281549 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGFR3 FGF7 14525934 25348397 8663044 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FGFR1 FGF7 25348397 N/A in vitro ComPPI
COL2A1 FGF7 11973338 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
COL3A1 FGF7 11973338 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HSPG2 FGF7 10702276 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,solid phase assay,two hybrid ComPPI,HPRD,OmniPath
UBQLN1 FGF7 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
COL1A1 FGF7 11973338 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGFR4 FGF7 14525934 25348397 7680645 N/A experimental interaction detection,in vivo ComPPI,HPRD
FGF7 COL6A1 11973338 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGF7 DESI1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FGF7 NRP1 14525934 15695515 N/A experimental interaction detection HPRD
FGF7 FGFR2 10339576 10950949 11121055 27898060 7687739 8663044 9582367 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
NUDT6 FGF7 27087310 7999082 direct interaction,inhibition N/A NPInter

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