Gene Information gene info

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GENE：GSTO2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GSTO2
FullNmae glutathione S-transferase omega 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23064
EnsembleID ENSG00000065621
Uniprot Q9H4Y5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GSTO2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GSTO2 GO:0004364,GO:0005515,GO:0005737,GO:0005829,GO:0006749,GO:0006805,GO:0016491,GO:0019852,GO:0019852,GO:0042802,GO:0045174,GO:0045174,GO:0050610,GO:0070062,GO:0071243,GO:0098869

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GSTO2 hsa:119391 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa05200 Pathways in cancer - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa05204 Chemical carcinogenesis - DNA adducts - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
GSTO2 hsa:119391 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GSTO2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GSTO2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GSTO2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GSTO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000000EF0B GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003804D8 GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 GSTO2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C GSTO2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000072B4C8 GSTO2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC379 GSTO2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E GSTO2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000075A513 GSTO2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA GSTO2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001F9A0F GSTO2 23706177 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SMARCC1 GSTO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FKBP1A GSTO2 25348397 N/A physical interaction ComPPI
CPNE1 GSTO2 25348397 N/A physical interaction ComPPI
TFAP2A GSTO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TXN GSTO2 25348397 N/A physical interaction ComPPI
PFDN5 GSTO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WDR1 GSTO2 25348397 N/A physical interaction ComPPI
INCA1 GSTO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SAV1 GSTO2 22570112 24234451 25348397 physical association two hybrid ComPPI,IntAct
NTAQ1 GSTO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HINT1 GSTO2 25348397 N/A physical interaction ComPPI
HOXC8 GSTO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLR1C GSTO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAGLN2 GSTO2 25348397 N/A physical interaction ComPPI

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