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GENE：HDAC9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HDAC9
FullNmae histone deacetylase 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14065
EnsembleID ENSG00000048052
Uniprot Q9UKV0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HDAC9 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HDAC9 GO:0000118,GO:0000122,GO:0001818,GO:0001975,GO:0003714,GO:0004407,GO:0005080,GO:0005515,GO:0005634,GO:0005654,GO:0005667,GO:0005737,GO:0005737,GO:0006954,GO:0007507,GO:0030182,GO:0030183,GO:0031078,GO:0032129,GO:0032869,GO:0033558,GO:0034739,GO:0034983,GO:0035097,GO:0042113,GO:0042632,GO:0042826,GO:0045814,GO:0045814,GO:0045892,GO:0046872,GO:0048742,GO:0051005,GO:0051153,GO:0061629,GO:0061629,GO:0090050,GO:0140297,GO:0140297,GO:0140297

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HDAC9 hsa:9734 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
HDAC9 hsa:9734 path:hsa05034 Alcoholism - Homo sapiens (human)
HDAC9 hsa:9734 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HDAC9 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR HDAC9 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 HDAC9 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 HDAC9 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 HDAC9 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 HDAC9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BCL6 HDAC9 11929873 trascriptional regulation,stimulation inferred by curator TFlink
GATA4 HDAC9 18332107 trascriptional regulation,stimulation inferred by curator TFlink
MEF2D HDAC9 15171250 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 HDAC9 21243522 trascriptional regulation,stimulation inferred by curator TFlink
RELA HDAC9 21243522 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000148B91 HDAC9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 HDAC9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 HDAC9 25416803 26441331 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CAMK1 HDAC9 22135298 phosphorylation N/A PhosphoSite
PKN1 HDAC9 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MORF4L2 HDAC9 25348397 N/A physical interaction ComPPI
MAPK9 HDAC9 25348397 N/A physical interaction ComPPI
FIP1L1 HDAC9 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HEY2 HDAC9 25348397 N/A physical interaction ComPPI
H4C1 HDAC9 25348397 N/A physical interaction ComPPI
SYK HDAC9 25348397 N/A physical interaction ComPPI
MAPK8 HDAC9 25348397 N/A physical interaction ComPPI
MAML1 HDAC9 20203086 25348397 27898060 N/A physical interaction ComPPI,OmniPath
JUN HDAC9 25348397 N/A physical interaction ComPPI
SUMO1 HDAC9 12590135 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HDAC3 HDAC9 10655483 11466315 12590135 14525934 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD
CEBPB HDAC9 25348397 N/A physical interaction ComPPI
CTBP1 HDAC9 11022042 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HDAC4 HDAC9 12590135 14525934 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD
NCOR1 HDAC9 11466315 12590135 14525934 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
YWHAZ HDAC9 25348397 N/A physical interaction ComPPI
PKD1 HDAC9 25348397 N/A physical interaction ComPPI
PARP1 HDAC9 25348397 N/A physical interaction ComPPI
RBM14 HDAC9 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCA4 HDAC9 25348397 N/A physical interaction ComPPI
SIN3A HDAC9 12590135 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TPR HDAC9 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM29 HDAC9 20947501 25348397 27898060 N/A physical interaction ComPPI,OmniPath
EIF6 HDAC9 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MKI67 HDAC9 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RCC1 HDAC9 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TMPO HDAC9 25348397 N/A physical interaction ComPPI
ZBTB16 HDAC9 12590135 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SUMO2 HDAC9 12590135 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK10 HDAC9 25348397 N/A physical interaction ComPPI
CBX5 HDAC9 12242305 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SFN HDAC9 25348397 N/A physical interaction ComPPI
YWHAE HDAC9 15166223 20936779 24234451 25348397 27898060 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct,OmniPath
H3C15 HDAC9 25348397 N/A physical interaction ComPPI
USF1 HDAC9 14525934 19303849 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
MEF2C HDAC9 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MEF2A HDAC9 10825153 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SMC3 HDAC9 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETV6 HDAC9 12590135 14525934 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CAMK1 HDAC9 25348397 N/A physical interaction ComPPI
RFXANK HDAC9 25348397 N/A physical interaction ComPPI
SIN3B HDAC9 12590135 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ANKRA2 HDAC9 25348397 N/A physical interaction ComPPI
WNK1 HDAC9 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HDAC9 HDAC1 10487760 10655483 12590135 14525934 16611996 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
HDAC9 FOXP3 17360565 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 ESR1 25348397 N/A physical interaction ComPPI
HDAC9 NUP214 25348397 N/A physical interaction ComPPI
HDAC9 MEF2B 25348397 N/A physical interaction ComPPI
HDAC9 TP53 25348397 N/A physical interaction ComPPI
HDAC9 BCL6 12590135 16147992 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 HINT1 25348397 N/A physical interaction ComPPI
HDAC9 TOP1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 ADAR 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 H1-10 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 TMPO 25348397 N/A physical interaction ComPPI
HDAC9 NUP93 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 CCAR2 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 NOP2 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 TPX2 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 ZC3H11A 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC9 MYCN 25348397 N/A physical interaction ComPPI
H3-3A HDAC9 25348397 N/A physical interaction ComPPI
AURKB HDAC9 22865920 27898060 inhibition N/A OmniPath
PKN1 HDAC9 20188095 27898060 N/A N/A OmniPath

Visualization










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