Gene Information gene info

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GENE：AKR1B10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AKR1B10
FullNmae aldo-keto reductase family 1 member B10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:382
EnsembleID ENSG00000198074
Uniprot O60218

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AKR1B10 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AKR1B10 GO:0001523,GO:0001523,GO:0001758,GO:0004032,GO:0004033,GO:0005515,GO:0005576,GO:0005739,GO:0005764,GO:0005829,GO:0005829,GO:0008106,GO:0016488,GO:0042572,GO:0044597,GO:0044598,GO:0045550,GO:0047655,GO:0047718,GO:0052650,GO:0110095

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
AKR1B10 hsa:57016 path:hsa00040 Pentose and glucuronate interconversions - Homo sapiens (human)
AKR1B10 hsa:57016 path:hsa00051 Fructose and mannose metabolism - Homo sapiens (human)
AKR1B10 hsa:57016 path:hsa00052 Galactose metabolism - Homo sapiens (human)
AKR1B10 hsa:57016 path:hsa00561 Glycerolipid metabolism - Homo sapiens (human)
AKR1B10 hsa:57016 path:hsa00790 Folate biosynthesis - Homo sapiens (human)
AKR1B10 hsa:57016 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR AKR1B10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 AKR1B10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AKR1B10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AKR1B10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 AKR1B10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AKR1B10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AKR1B10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 AKR1B10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC AKR1B10 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004F4657 AKR1B10 21351259 rna interference,inhibition array technology,experimental interaction detection miRSponge
URS00004F4657 AKR1B10 21351259 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS0000122ED0 AKR1B10 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00002AB575 AKR1B10 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000AF45F AKR1B10 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA AKR1B10 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004B83FE AKR1B10 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 AKR1B10 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA AKR1B10 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A AKR1B10 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 AKR1B10 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D AKR1B10 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C AKR1B10 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 AKR1B10 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF AKR1B10 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008B558 AKR1B10 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ACACA AKR1B10 25361965 interaction type N/A PTMCode2
AKR1B10 ACACA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TBC1D22B AKR1B10 25348397 N/A physical interaction ComPPI
PDE4DIP AKR1B10 25348397 N/A physical interaction ComPPI
TSNAX AKR1B10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NOS2 AKR1B10 25348397 N/A physical interaction ComPPI
PGK1 AKR1B10 25348397 N/A physical interaction ComPPI
TERF2IP AKR1B10 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PCBP3 AKR1B10 25348397 N/A physical interaction ComPPI
DDX19B AKR1B10 25348397 N/A physical interaction ComPPI
HNRNPA1 AKR1B10 25348397 N/A physical interaction ComPPI
HINT1 AKR1B10 25348397 N/A physical interaction ComPPI
CDK15 AKR1B10 25348397 N/A physical interaction ComPPI
ACACA AKR1B10 18056116 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct,OmniPath
AKR1B10 AKR1B15 25348397 N/A physical interaction ComPPI
AKR1B10 POTEF 25348397 N/A physical interaction ComPPI
AKR1B10 AKR1D1 25348397 N/A physical interaction ComPPI
VDAC1 AKR1B10 24234451 30021884 physical association cross-linking study IntAct

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