Gene Information gene info

GENE:CCNH

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CCNH
FullNmae cyclin H
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1594
EnsembleID ENSG00000134480
Uniprot P51946

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CCNH pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNH mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCNH immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CCNH GO:0000079,GO:0000439,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005675,GO:0006357,GO:0006366,GO:0006367,GO:0007049,GO:0016251,GO:0016538,GO:0019907,GO:0019907,GO:0050821,GO:0070516,GO:0070985,GO:0070985,GO:2000045

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CCNH hsa:902 path:hsa03022 Basal transcription factors - Homo sapiens (human)
CCNH hsa:902 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)
CCNH hsa:902 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CCNH CTBP2 21988832 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR CCNH 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CCNH 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CCNH 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CCNH 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CCNH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CCNH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CCNH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CCNH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CCNH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CCNH N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000FC8EB CCNH 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 CCNH 22135298 phosphorylation N/A PhosphoSite
CSNK2A2 CCNH 22135298 phosphorylation N/A PhosphoSite
CDK8 CCNH 22135298 phosphorylation N/A PhosphoSite
CCNH MNAT1 25361965 interaction type N/A PTMCode2
MNAT1 CCNH 25361965 interaction type N/A PTMCode2
CCNH CDK2 25361965 interaction type N/A PTMCode2
CDK2 CCNH 25361965 interaction type N/A PTMCode2
CCNH TP53 25361965 interaction type N/A PTMCode2
TP53 CCNH 25361965 interaction type N/A PTMCode2
CCNH GTF2H2 25361965 interaction type N/A PTMCode2
GTF2H2 CCNH 25361965 interaction type N/A PTMCode2
CCNH CDK5 25361965 interaction type N/A PTMCode2
CDK5 CCNH 25361965 interaction type N/A PTMCode2
CCNH MCM7 25361965 interaction type N/A PTMCode2
MCM7 CCNH 25361965 interaction type N/A PTMCode2
CCNH GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 CCNH 25361965 interaction type N/A PTMCode2
CCNH CDK9 25361965 interaction type N/A PTMCode2
CDK9 CCNH 25361965 interaction type N/A PTMCode2
CCNH SUPT5H 25361965 interaction type N/A PTMCode2
SUPT5H CCNH 25361965 interaction type N/A PTMCode2
CCNH ERCC2 25361965 interaction type N/A PTMCode2
ERCC2 CCNH 25361965 interaction type N/A PTMCode2
POLR2I CCNH 25361965 interaction type N/A PTMCode2
CCNH POLR2I 25361965 interaction type N/A PTMCode2
CDK7 CCNH 25361965 interaction type N/A PTMCode2
CCNH CDK7 25361965 interaction type N/A PTMCode2
CCNB1 CCNH 25361965 interaction type N/A PTMCode2
CCNH CCNB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 CCNH 21516116 21988832 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH NDC80 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH ZNRD2 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
CCNH PPFIA1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH CCDC170 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH DUSP12 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH GTF2E2 11113176 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CCNH GTF2H1 10734143 14525934 24234451 25348397 26340423 7533895 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
CCNH CDK8 10993082 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNH MTA1 12527756 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNH FUBP1 25348397 N/A physical interaction,in vitro ComPPI
CCNH CDK7 14525934 23602568 24234451 25348397 26340423 29568061 8078587 8521818 9056480 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,cross-linking study,experimental interaction detection,pull down,physical interaction,protein kinase assay,in vivo,tandem affinity purification,proximity-dependent biotin identification,two hybrid ComPPI,HPRD,IntAct
CCNH PSMA1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
CCNH CDK2 14525934 24234451 25348397 26496610 8521818 9464540 9840943 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,protein kinase assay,in vitro ComPPI,HPRD,IntAct
CCNH ESR1 12527756 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CCNH AR 10734072 14525934 25348397 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CCNH CDK20 25348397 N/A two hybrid,physical interaction ComPPI
CCNH ERCC3 10734143 14525934 24234451 25348397 26340423 9118947 association,physical association anti bait coimmunoprecipitation,cross-linking study,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CCNH MCM7 11056214 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CCNH MNAT1 17353931 24234451 25348397 26340423 8521818 phosphorylation reaction,physical association anti bait coimmunoprecipitation,cross-linking study,physical interaction,protein kinase assay ComPPI,IntAct
CCNH RADIL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNH TP53 14525934 25348397 9840937 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CCNH GTF2H2 24234451 25348397 26340423 physical association cross-linking study,physical interaction ComPPI,IntAct
CCNH SUPT5H 25348397 N/A physical interaction ComPPI
CCNH MYC 25348397 N/A physical interaction ComPPI
CCNH ERCC2 24234451 25348397 26340423 physical association cross-linking study,physical interaction ComPPI,IntAct
CCNH POLR2B 25348397 N/A physical interaction ComPPI
CCNH CDK9 25348397 N/A physical interaction ComPPI
CCNH BRCA1 25348397 N/A physical interaction ComPPI
CCNH GTF2H4 19172752 24234451 25348397 26340423 association,physical association anti bait coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
CCNH POLR2A 25348397 N/A physical interaction ComPPI
CCNH CCNC 25348397 N/A physical interaction ComPPI
CCNH CTBP2 21988832 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid array,confocal microscopy ComPPI,IntAct
CCNH TRIM8 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CCNH CSNK2B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CCNH RARB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CCNH GANAB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CCNH SSX2IP 21988832 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH RPA3 25348397 N/A physical interaction ComPPI
CCNH RPA2 25348397 N/A physical interaction ComPPI
CCNH RPA1 25348397 N/A physical interaction ComPPI
CCNH NEDD4 25348397 N/A physical interaction ComPPI
CCNH SFN 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH CALCOCO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH CCDC33 25348397 N/A physical interaction ComPPI
CCNH KLC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CCNH TBC1D15 25348397 N/A physical interaction ComPPI
CCNH ERCC5 25348397 N/A physical interaction ComPPI
CCNH BIVM 25348397 N/A physical interaction ComPPI
CCNH CPSF4L 25348397 N/A physical interaction ComPPI
CCNH PTBP1 25348397 N/A physical interaction ComPPI
CCNH HNRNPF 25348397 N/A physical interaction ComPPI
CCNH GTF2H5 24234451 25348397 26340423 26496610 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
CCNH MTMR7 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH RARA 16769902 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CCNH XPC 10734143 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CCNH CDK6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH TRIML2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH BLZF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH CCT4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH SORBS3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH PICK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH GRIPAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH ZNF655 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCNH GTF2H3 24234451 25348397 26340423 physical association cross-linking study ComPPI,IntAct
CCNH CDK7 10082552 10958691 11113184 11713533 15328539 15698475 16782892 17643375 19153657 22939629 23602568 26186194 26344197 27898060 8078587 8521393 8521818 8692841 9056480 9218599 9334327 stimulant N/A OmniPath
DAPK3 CCNH 12140753 27898060 N/A N/A OmniPath
CDK8 CCNH 10993082 27898060 inhibition,stimulant N/A OmniPath
CSNK2A2 CCNH 12140753 20624369 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009C0A98 CCNH 27087310 direct interaction,inhibition N/A NPInter

Visualization