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GENE：COL5A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COL5A1
FullNmae collagen type V alpha 1 chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2209
EnsembleID ENSG00000130635
Uniprot P20908

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COL5A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
COL5A1 GO:0001568,GO:0003007,GO:0005178,GO:0005515,GO:0005576,GO:0005576,GO:0005588,GO:0005588,GO:0005588,GO:0005604,GO:0005615,GO:0005788,GO:0007155,GO:0007155,GO:0008201,GO:0008201,GO:0016477,GO:0030020,GO:0030020,GO:0030020,GO:0030199,GO:0030199,GO:0030199,GO:0032964,GO:0035313,GO:0035989,GO:0043394,GO:0043588,GO:0045112,GO:0046872,GO:0048407,GO:0048592,GO:0051128,GO:0062023,GO:0062023,GO:0062023,GO:0097435,GO:1903225

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
COL5A1 hsa:1289 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR COL5A1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 COL5A1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 COL5A1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 COL5A1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 COL5A1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP1 COL5A1 7646438 trascriptional regulation,stimulation electrophoretic mobility shift assay TFlink
TFAP2C COL5A1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 COL5A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 COL5A1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EC1BE COL5A1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004F4657 COL5A1 23108408 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry TarBase
URS0000008A99 COL5A1 22942087 25416803 mrna cleavage,inhibition array technology TarBase
URS000019F055 COL5A1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 COL5A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 COL5A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D COL5A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 COL5A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 COL5A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 COL5A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 COL5A1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD COL5A1 25416803 25827718 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
DCN COL5A1 25361965 interaction type N/A PTMCode2
COL5A1 DCN 25361965 interaction type N/A PTMCode2
COL11A1 COL5A1 25361965 interaction type N/A PTMCode2
COL5A1 COL11A1 25361965 interaction type N/A PTMCode2
SPARC COL5A1 25361965 interaction type N/A PTMCode2
COL5A1 SPARC 25361965 interaction type N/A PTMCode2
THBS1 COL5A1 25361965 interaction type N/A PTMCode2
COL5A1 THBS1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
COL1A2 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
C1QTNF2 COL5A1 25348397 N/A physical interaction ComPPI
TGFB1 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
TGM2 COL5A1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COL6A2 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
SPARC COL5A1 25348397 N/A physical interaction ComPPI
THBS1 COL5A1 14525934 25348397 27898060 6693501 9840442 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
PCOLCE COL5A1 20979576 24234451 25348397 physical association two hybrid,surface plasmon resonance ComPPI,IntAct
PTPN1 COL5A1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDGFB COL5A1 25348397 N/A physical interaction ComPPI
PTPN2 COL5A1 25348397 N/A physical interaction ComPPI
PDGFA COL5A1 25348397 N/A physical interaction ComPPI
HNRNPL COL5A1 25348397 N/A physical interaction ComPPI
CSNK2A2 COL5A1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TIMP1 COL5A1 20979576 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid ComPPI,IntAct
TRIM25 COL5A1 25348397 N/A physical interaction ComPPI
BMP1 COL5A1 11741999 14525934 20979576 24234451 25348397 physical association experimental interaction detection,protease assay ComPPI,HPRD,IntAct
COL1A1 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
MMP2 COL5A1 20979576 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
MMP9 COL5A1 25348397 N/A physical interaction ComPPI
COL6A1 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
PRSS23 COL5A1 25348397 N/A physical interaction ComPPI
MAG COL5A1 25348397 N/A physical interaction ComPPI
COL6A3 COL5A1 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
SIRT7 COL5A1 25348397 N/A physical interaction ComPPI
PLOD1 COL5A1 25348397 N/A physical interaction ComPPI
TNC COL5A1 20979576 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid ComPPI,IntAct
COL5A1 FN1 20979576 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid ComPPI,IntAct
COL5A1 GALNT7 20979576 24234451 25348397 physical association two hybrid ComPPI,IntAct
DCN COL5A1 14525934 27898060 8440685 N/A experimental interaction detection HPRD,OmniPath
COL5A3 COL5A1 10722718 14525934 6501291 7346227 N/A experimental interaction detection HPRD
SDC3 COL5A1 11751872 14525934 N/A experimental interaction detection HPRD
LGALS3BP COL5A1 14525934 9501082 N/A experimental interaction detection HPRD
SUGP2 COL5A1 24234451 30021884 physical association cross-linking study IntAct
BMP1 COL5A1 11741999 27898060 N/A N/A OmniPath

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