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GENE：EMSY

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EMSY
FullNmae EMSY transcriptional repressor, BRCA2 interacting
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18071
EnsembleID ENSG00000158636
Uniprot Q7Z589

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EMSY immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EMSY GO:0005515,GO:0005654,GO:0005654,GO:0006281,GO:0006325,GO:0006355,GO:0042802

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 EMSY 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 EMSY 18971253 20019798 24582497 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 EMSY 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A EMSY 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 EMSY 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 EMSY 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 EMSY 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 EMSY 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000001EB3 EMSY 24582497 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000042E1F EMSY 20371350 21572407 22012620 22473208 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 EMSY 20371350 21572407 22012620 22473208 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 EMSY 20371350 21572407 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE EMSY 20371350 21572407 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA EMSY 20371350 21572407 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B EMSY 20371350 21572407 22012620 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 EMSY 20371350 21572407 22012620 22473208 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 EMSY 20371350 21572407 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 EMSY 20371350 21572407 22012620 22473208 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 EMSY 20371350 21572407 22012620 22473208 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA EMSY 20371350 21572407 22012620 22473208 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 EMSY 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 EMSY 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AKT1 EMSY 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
BCAS2 EMSY 25348397 N/A physical interaction ComPPI
KRT18 EMSY 25348397 N/A physical interaction ComPPI
MORF4L2 EMSY 25348397 N/A physical interaction ComPPI
SNRPA1 EMSY 25348397 N/A physical interaction ComPPI
TP53BP1 EMSY 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
CBX1 EMSY 14525934 14651845 15947784 16615912 24234451 25348397 27898060 N/A experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
ASH2L EMSY 25348397 N/A physical interaction ComPPI
BRCA2 EMSY 14525934 14651845 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NUP98 EMSY 25348397 N/A physical interaction ComPPI
RBBP5 EMSY 25348397 N/A physical interaction ComPPI
KDM5A EMSY 25348397 N/A physical interaction ComPPI
MORF4L1 EMSY 25348397 N/A physical interaction ComPPI
CSNK2A2 EMSY 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SON EMSY 25348397 N/A physical interaction ComPPI
H3-4 EMSY 25348397 N/A physical interaction ComPPI
HDAC2 EMSY 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MDC1 EMSY 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
BCOR EMSY 24234451 25348397 27505670 association tandem affinity purification ComPPI,IntAct
SIN3B EMSY 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMSY ZMYND11 14525934 14651845 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EMSY ZNF335 25348397 N/A physical interaction ComPPI
EMSY CCAR2 25348397 N/A physical interaction ComPPI
EMSY TADA2A 25348397 N/A physical interaction ComPPI
EMSY HDAC1 23752268 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMSY DDIT3 25348397 N/A physical interaction ComPPI
EMSY ZNF646 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EMSY MOV10 25348397 N/A physical interaction ComPPI
EMSY NXF1 25348397 N/A physical interaction ComPPI
EMSY GATAD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMSY TMEM171 25348397 N/A physical interaction ComPPI
EMSY DYNLT1 25348397 N/A physical interaction ComPPI
EMSY RTEL1 25348397 N/A physical interaction ComPPI
EMSY PHF12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMSY KIF7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMSY FOXJ2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EMSY FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EMSY ZNF281 25348397 N/A physical interaction ComPPI
EMSY ZNF131 25348397 N/A physical interaction ComPPI
EMSY RBBP7 25348397 N/A physical interaction ComPPI
EMSY QSER1 25348397 N/A physical interaction ComPPI
EMSY CHD9 25348397 N/A physical interaction ComPPI
EMSY AKAP8 25348397 N/A physical interaction ComPPI
EMSY NUP214 25348397 N/A physical interaction ComPPI
EMSY HNRNPM 25348397 N/A physical interaction ComPPI
EMSY PHC3 25348397 N/A physical interaction ComPPI
EMSY NUP88 25348397 N/A physical interaction ComPPI
EMSY NCAPH2 25348397 N/A physical interaction ComPPI
EMSY TCTE1 24234451 25348397 26638075 association proximity-dependent biotin identification ComPPI,IntAct
EMSY BRCA1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
TRIM26 EMSY 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCB1 EMSY 24234451 30108113 association proximity-dependent biotin identification IntAct
H1-5 EMSY 24234451 30021884 physical association cross-linking study IntAct
AKT1 EMSY 22315412 27898060 N/A N/A OmniPath

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