Gene Information gene info

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GENE：PSMA4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMA4
FullNmae proteasome 20S subunit alpha 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9533
EnsembleID ENSG00000041357
Uniprot P25789

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMA4 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMA4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMA4 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMA4 GO:0000502,GO:0000502,GO:0000932,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0005839,GO:0005839,GO:0010498,GO:0019773,GO:0019773,GO:0019773,GO:0043161,GO:0043231,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMA4 hsa:5685 path:hsa03050 Proteasome - Homo sapiens (human)
PSMA4 hsa:5685 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMA4 hsa:5685 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMA4 hsa:5685 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMA4 hsa:5685 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMA4 hsa:5685 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMA4 hsa:5685 path:hsa05020 Prion disease - Homo sapiens (human)
PSMA4 hsa:5685 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PSMA4 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PSMA4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PSMA4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PSMA4 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PSMA4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PSMA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PSMA4 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000005481D PSMA4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PSMA4 PSMC4 25361965 interaction type N/A PTMCode2
PSMC4 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMD8 25361965 interaction type N/A PTMCode2
PSMD8 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMA3 25361965 interaction type N/A PTMCode2
PSMA3 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMD7 25361965 interaction type N/A PTMCode2
PSMD7 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB3 25361965 interaction type N/A PTMCode2
PSMB3 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB7 25361965 interaction type N/A PTMCode2
PSMB7 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMC1 25361965 interaction type N/A PTMCode2
PSMC1 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMA6 25361965 interaction type N/A PTMCode2
PSMA6 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMD11 25361965 interaction type N/A PTMCode2
PSMD11 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB1 25361965 interaction type N/A PTMCode2
PSMB1 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB6 25361965 interaction type N/A PTMCode2
PSMB6 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMA5 25361965 interaction type N/A PTMCode2
PSMA5 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB4 25361965 interaction type N/A PTMCode2
PSMB4 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMD6 25361965 interaction type N/A PTMCode2
PSMD6 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMC3 25361965 interaction type N/A PTMCode2
PSMC3 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMD1 25361965 interaction type N/A PTMCode2
PSMD1 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMA1 25361965 interaction type N/A PTMCode2
PSMA1 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 CUL1 25361965 interaction type N/A PTMCode2
CUL1 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB10 25361965 interaction type N/A PTMCode2
PSMB10 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMD14 25361965 interaction type N/A PTMCode2
PSMD14 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMB9 25361965 interaction type N/A PTMCode2
PSMB9 PSMA4 25361965 interaction type N/A PTMCode2
PSMA4 PSMC6 25361965 interaction type N/A PTMCode2
PSMC6 PSMA4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EXOSC5 PSMA4 25348397 N/A physical interaction ComPPI
GOLGA2 PSMA4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRIM38 PSMA4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GET3 PSMA4 25348397 N/A physical interaction ComPPI
PPIB PSMA4 25348397 N/A physical interaction ComPPI
PSMC3 PSMA4 25348397 N/A physical interaction ComPPI
PSMC6 PSMA4 25348397 N/A physical interaction ComPPI
KIF5B PSMA4 25348397 N/A physical interaction ComPPI
PSMD14 PSMA4 25348397 N/A physical interaction ComPPI
TRAF6 PSMA4 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PSMD7 PSMA4 25348397 N/A physical interaction ComPPI
VCP PSMA4 25348397 N/A physical interaction ComPPI
RAN PSMA4 25348397 N/A physical interaction ComPPI
SKP1 PSMA4 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
KEAP1 PSMA4 25348397 N/A physical interaction ComPPI
PSMB2 PSMA4 25348397 N/A physical interaction ComPPI
AP3M1 PSMA4 25348397 N/A physical interaction ComPPI
FBXW7 PSMA4 25348397 N/A physical interaction ComPPI
JUN PSMA4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
HIF1A PSMA4 22801492 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA3 PSMA4 14525934 14733938 15225636 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PSMD11 PSMA4 25348397 N/A physical interaction ComPPI
U2AF2 PSMA4 25348397 N/A physical interaction ComPPI
UBB PSMA4 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBC PSMA4 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RPS27A PSMA4 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBA52 PSMA4 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
NTRK1 PSMA4 25348397 N/A physical interaction ComPPI
YBX1 PSMA4 25348397 N/A physical interaction ComPPI
PLK1 PSMA4 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PSMA1 PSMA4 12376572 14525934 15225636 24234451 25348397 25599644 29568061 association,physical association affinity chromatography technology,cosedimentation in solution,experimental interaction detection,pull down,x-ray crystallography,physical interaction,in vitro,proximity-dependent biotin identification ComPPI,HPRD,IntAct
PSMA6 PSMA4 14525934 15225636 17948026 19581590 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PSMA5 PSMA4 14525934 15225636 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PSMB9 PSMA4 25348397 N/A physical interaction ComPPI
MYC PSMA4 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NFKBIA PSMA4 24234451 24509793 25348397 physical association pull down,physical interaction ComPPI,IntAct
CSNK2A1 PSMA4 14525934 25348397 8619999 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CFTR PSMA4 25348397 N/A physical interaction ComPPI
EIF6 PSMA4 25348397 N/A physical interaction ComPPI
PSMD8 PSMA4 25348397 N/A physical interaction ComPPI
EWSR1 PSMA4 25348397 N/A physical interaction ComPPI
PSMB8 PSMA4 25348397 N/A physical interaction ComPPI
PSMD1 PSMA4 25348397 N/A physical interaction ComPPI
SDCBP PSMA4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMC5 PSMA4 25348397 N/A physical interaction ComPPI
HUWE1 PSMA4 25348397 N/A physical interaction ComPPI
RAD23A PSMA4 25348397 N/A physical interaction ComPPI
UBA2 PSMA4 25348397 N/A physical interaction ComPPI
HNRNPA2B1 PSMA4 25348397 N/A physical interaction ComPPI
NEDD8 PSMA4 25348397 N/A physical interaction ComPPI
EPB41L1 PSMA4 25348397 N/A physical interaction ComPPI
CUL1 PSMA4 25348397 N/A physical interaction ComPPI
EGFR PSMA4 25348397 N/A physical interaction ComPPI
PSMC4 PSMA4 25348397 N/A physical interaction ComPPI
NOS2 PSMA4 25348397 N/A physical interaction ComPPI
PSMD2 PSMA4 25348397 N/A physical interaction ComPPI
VCAM1 PSMA4 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
DNM1L PSMA4 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRKN PSMA4 25348397 N/A physical interaction ComPPI
PSMD4 PSMA4 25348397 N/A physical interaction ComPPI
EXOSC4 PSMA4 25348397 N/A physical interaction ComPPI
FKBP8 PSMA4 25348397 N/A physical interaction ComPPI
NFKB1 PSMA4 25348397 N/A physical interaction ComPPI
IKZF1 PSMA4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TFIP11 PSMA4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BUB1B PSMA4 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMURF1 PSMA4 25348397 N/A physical interaction ComPPI
PSMB5 PSMA4 25348397 N/A physical interaction ComPPI
PSME3 PSMA4 25348397 N/A physical interaction ComPPI
PSME1 PSMA4 25348397 N/A physical interaction ComPPI
PSME2 PSMA4 25348397 N/A physical interaction ComPPI
PSMC1 PSMA4 25348397 N/A physical interaction ComPPI
AMFR PSMA4 25348397 N/A physical interaction ComPPI
XPOT PSMA4 25348397 N/A physical interaction ComPPI
PSMB4 PSMA4 25348397 N/A physical interaction ComPPI
PSMB1 PSMA4 25348397 N/A physical interaction ComPPI
PSMB3 PSMA4 25348397 N/A physical interaction ComPPI
PSMB7 PSMA4 20723761 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 PSMA4 14525934 14733938 15225636 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
PSMA4 PSMA2 14525934 14733938 15225636 15887188 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PSMA4 BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA4 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA4 RNF185 25348397 N/A physical interaction ComPPI
PSMA4 PSMB6 25348397 N/A physical interaction ComPPI
PSMA4 ABL1 25348397 N/A physical interaction ComPPI
PSMA4 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA4 BHLHE41 25348397 N/A physical interaction ComPPI
PSMA4 PSMG2 17948026 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA4 POMP 17948026 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMA4 PSMC2 25348397 N/A physical interaction ComPPI
PSMA4 PSMD12 25348397 N/A physical interaction ComPPI
PSMA4 PSMD13 25348397 N/A physical interaction ComPPI
PSMA4 PSMD6 25348397 N/A physical interaction ComPPI
PSMA4 PSMD3 25348397 N/A physical interaction ComPPI
PSMA4 PSMD5 25348397 N/A physical interaction ComPPI
PSMA4 PSMA8 25348397 N/A physical interaction ComPPI
PSMA4 USP9X 25348397 N/A physical interaction ComPPI
PSMA4 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA4 ASB10 25348397 N/A physical interaction ComPPI
PSMA4 FBXO6 25348397 N/A physical interaction ComPPI
PSMA4 RPP38 25348397 N/A physical interaction ComPPI
PSMA4 PSME4 25348397 N/A physical interaction ComPPI
PSMA4 PYCR3 25348397 N/A physical interaction ComPPI
PSMA4 AMBRA1 25348397 N/A physical interaction ComPPI
PSMA4 CCAR2 25348397 N/A physical interaction ComPPI
PSMA4 ELP6 25348397 N/A physical interaction ComPPI
PSMA4 CHMP5 25348397 N/A physical interaction ComPPI
PSMA4 ERO1B 25348397 N/A physical interaction ComPPI
PSMA4 MRPS9 25348397 N/A physical interaction ComPPI
PSMA4 WDR11 25348397 N/A physical interaction ComPPI
PSMA4 RHOU 25348397 N/A physical interaction ComPPI
PSMA4 HERC3 25348397 N/A physical interaction ComPPI
PSMA4 CYLD 25348397 N/A physical interaction ComPPI
PSMA4 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PSMA4 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMA4 SHLD3 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
ADRM1 PSMA4 25348397 N/A physical interaction ComPPI
PSMA4 C2 14525934 8175701 N/A experimental interaction detection HPRD
PSMA4 PSMA4 14525934 15225636 24234451 physical association experimental interaction detection,pull down HPRD,IntAct

Visualization










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