GENE：RBP4
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RBP4 |
| FullNmae | retinol binding protein 4 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9922 |
| EnsembleID | ENSG00000138207 |
| Uniprot | P02753 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RBP4 | pyroptosis | 39706833 | NNMT inhibited the stability of RBP4 mRNA via m6A modification, thereby preventing pyroptosis following PI(4,5)P2 treatment. | retulator signature |
| RBP4 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RBP4 | GO:0001654,GO:0001654,GO:0002639,GO:0005515,GO:0005576,GO:0005615,GO:0005615,GO:0005615,GO:0006094,GO:0006094,GO:0007507,GO:0007601,GO:0016918,GO:0019841,GO:0019841,GO:0030277,GO:0030324,GO:0032024,GO:0032526,GO:0034632,GO:0034633,GO:0034633,GO:0042572,GO:0042593,GO:0048562,GO:0048706,GO:0048738,GO:0048807,GO:0060044,GO:0060059,GO:0060065,GO:0060068,GO:0060157,GO:0060347,GO:0070062 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | RBP4 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | RBP4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RBP4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | RBP4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TTR | RBP4 | 11853533 12593674 14525934 21777382 24234451 25348397 27898060 29997244 574085 8089102 | physical association | bioluminescence resonance energy transfer,experimental interaction detection,physical interaction,blue native page,in vitro,in vivo,luminescence based mammalian interactome mapping | ComPPI,HPRD,IntAct,OmniPath |
| FTH1 | RBP4 | 25348397 | N/A | physical interaction | ComPPI |
| GRB2 | RBP4 | 18624398 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RBBP6 | RBP4 | 25348397 | N/A | physical interaction | ComPPI |
| RBP4 | ALB | 14525934 25348397 27898060 571335 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| RBP4 | LAMTOR5 | 25348397 | N/A | physical interaction | ComPPI |
| RBP4 | MSRB3 | 25348397 | N/A | physical interaction | ComPPI |
| RBP4 | MARCKSL1 | 25348397 | N/A | physical interaction | ComPPI |
| RBP4 | POLR3D | 25348397 | N/A | physical interaction | ComPPI |
| RBP4 | KLHL24 | 25348397 | N/A | physical interaction | ComPPI |
| TRADD | RBP4 | 24234451 30561431 | association | virotrap | IntAct |