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GENE：SERPINB5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SERPINB5
FullNmae serpin family B member 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8949
EnsembleID ENSG00000206075
Uniprot P36952

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SERPINB5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SERPINB5 GO:0001533,GO:0002009,GO:0004867,GO:0005515,GO:0005615,GO:0005737,GO:0010951,GO:0016528,GO:0030198,GO:0050678,GO:0060512

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SERPINB5 hsa:5268 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
SERPINB5 hsa:5268 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SERPINB5 IRF6 16049006 23180781 physical association anti tag coimmunoprecipitation InnateDB
ISG15 SERPINB5 16009940 23180781 physical association anti tag coimmunoprecipitation,unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
AR SERPINB5 16304843 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
YBX1 SERPINB5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SERPINB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SERPINB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SERPINB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SERPINB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SERPINB5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SERPINB5 20197383 trascriptional regulation,stimulation inferred by curator TFlink
HDAC1 SERPINB5 10709100 trascriptional regulation,stimulation inferred by curator TFlink
SP1 SERPINB5 17376297 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 SERPINB5 17376297 trascriptional regulation,stimulation inferred by curator TFlink
SPDEF SERPINB5 12907642 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 SERPINB5 N/A trascriptional regulation,stimulation inferred by curator TFlink
TP63 SERPINB5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D SERPINB5 N/A 18270520 19253296 20693317 21636785 \N rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D SERPINB5 18270520 19253296 20693317 21636785 25416803 26296971 27409165 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,chromatin immunoprecipitation assay,rna immunoprecipitation,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 SERPINB5 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 SERPINB5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 SERPINB5 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003E1A9 SERPINB5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF SERPINB5 25416803 26296971 27409165 mrna cleavage,inhibition array technology,western blot,chromatin immunoprecipitation assay,rna immunoprecipitation,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRSS21 SERPINB5 25361965 interaction type N/A PTMCode2
SERPINB5 PRSS21 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TBC1D22B SERPINB5 25348397 N/A physical interaction ComPPI
PDE4DIP SERPINB5 25348397 N/A physical interaction ComPPI
MAPK9 SERPINB5 25348397 N/A physical interaction ComPPI
COL1A2 SERPINB5 25348397 N/A physical interaction ComPPI
KRAS SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ISG15 SERPINB5 25348397 N/A physical interaction ComPPI
GSTM3 SERPINB5 25348397 N/A physical interaction ComPPI
SMAD4 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HSP90AB1 SERPINB5 25348397 N/A physical interaction ComPPI
TBP SERPINB5 25348397 N/A physical interaction ComPPI
RHOA SERPINB5 25348397 N/A physical interaction ComPPI
HSP90AA1 SERPINB5 25348397 N/A physical interaction ComPPI
HSPA5 SERPINB5 25348397 N/A physical interaction ComPPI
CASP8 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HDLBP SERPINB5 25348397 N/A physical interaction ComPPI
EEF1A1 SERPINB5 25348397 N/A physical interaction ComPPI
GOLGA4 SERPINB5 25348397 N/A physical interaction ComPPI
UBA6 SERPINB5 25348397 N/A physical interaction ComPPI
ZRANB2 SERPINB5 25348397 N/A physical interaction ComPPI
TPI1 SERPINB5 25348397 N/A physical interaction ComPPI
SF3A1 SERPINB5 25348397 N/A physical interaction ComPPI
VRK1 SERPINB5 25348397 N/A physical interaction ComPPI
STK11 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
WWOX SERPINB5 25348397 N/A physical interaction ComPPI
NARS1 SERPINB5 25348397 N/A physical interaction ComPPI
PRDX6 SERPINB5 25348397 N/A physical interaction ComPPI
KHDRBS3 SERPINB5 25348397 N/A physical interaction ComPPI
LRRFIP1 SERPINB5 25348397 N/A physical interaction ComPPI
EIF2S2 SERPINB5 25348397 N/A physical interaction ComPPI
IL31RA SERPINB5 25348397 N/A physical interaction ComPPI
GDF5 SERPINB5 25348397 N/A physical interaction ComPPI
ESR1 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AKT1 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXL4 SERPINB5 25348397 N/A physical interaction ComPPI
SOD1 SERPINB5 25348397 N/A physical interaction ComPPI
RAB11B SERPINB5 25348397 N/A physical interaction ComPPI
XRCC3 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DDX19B SERPINB5 25348397 N/A physical interaction ComPPI
PPIF SERPINB5 25348397 N/A physical interaction ComPPI
BCAR3 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UCHL5 SERPINB5 25348397 N/A physical interaction ComPPI
SYT16 SERPINB5 25348397 N/A physical interaction ComPPI
ALDH2 SERPINB5 25348397 N/A physical interaction ComPPI
GSTO1 SERPINB5 25348397 N/A physical interaction ComPPI
ZC3H11A SERPINB5 25348397 N/A physical interaction ComPPI
KHDC4 SERPINB5 25348397 N/A physical interaction ComPPI
C11ORF54 SERPINB5 25348397 N/A physical interaction ComPPI
PPIL3 SERPINB5 25348397 N/A physical interaction ComPPI
CBFB SERPINB5 25348397 N/A physical interaction ComPPI
GPBP1 SERPINB5 25348397 N/A physical interaction ComPPI
TKT SERPINB5 25348397 N/A physical interaction ComPPI
MDH1 SERPINB5 25348397 N/A physical interaction ComPPI
SNX3 SERPINB5 25348397 N/A physical interaction ComPPI
PALB2 SERPINB5 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GLOD4 SERPINB5 25348397 N/A physical interaction ComPPI
SLX4 SERPINB5 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ADA SERPINB5 25348397 N/A physical interaction ComPPI
RBM24 SERPINB5 25348397 N/A physical interaction ComPPI
MT1H SERPINB5 25348397 N/A physical interaction ComPPI
EEF1A1P5 SERPINB5 25348397 N/A physical interaction ComPPI
HDAC1 SERPINB5 25348397 N/A physical interaction ComPPI
ATIC SERPINB5 25348397 N/A physical interaction ComPPI
SGO2 SERPINB5 25348397 N/A physical interaction ComPPI
CCDC82 SERPINB5 25348397 N/A physical interaction ComPPI
CDK15 SERPINB5 25348397 N/A physical interaction ComPPI
HDGFL2 SERPINB5 25348397 N/A physical interaction ComPPI
HSP90AA2P SERPINB5 25348397 N/A physical interaction ComPPI
KIF3A SERPINB5 25348397 N/A physical interaction ComPPI
KIR3DS1 SERPINB5 25348397 N/A physical interaction ComPPI
EIF2A SERPINB5 25348397 N/A physical interaction ComPPI
FBXO32 SERPINB5 25348397 N/A physical interaction ComPPI
DDX46 SERPINB5 25348397 N/A physical interaction ComPPI
ACAD9 SERPINB5 25348397 N/A physical interaction ComPPI
PYHIN1 SERPINB5 25348397 N/A physical interaction ComPPI
SERPINB5 PLS1 25348397 N/A physical interaction ComPPI
SERPINB5 HMGCS1 25348397 N/A physical interaction ComPPI
SERPINB5 NAA50 25348397 N/A physical interaction ComPPI
SERPINB5 GPR18 25348397 N/A physical interaction ComPPI
SERPINB5 UGT1A10 25348397 N/A physical interaction ComPPI
SERPINB5 LACC1 24234451 25348397 27478939 association affinity chromatography technology,physical interaction ComPPI,IntAct
SERPINB5 RAB9B 25348397 N/A physical interaction ComPPI
SERPINB5 ITPA 25348397 N/A physical interaction ComPPI
SERPINB5 FCF1 25348397 N/A physical interaction ComPPI
SERPINB5 CCNYL1 25348397 N/A physical interaction ComPPI
SERPINB5 CPLX3 25348397 N/A physical interaction ComPPI
SERPINB5 FRMD1 25348397 N/A physical interaction ComPPI
SERPINB5 BASP1 25348397 N/A physical interaction ComPPI
SERPINB5 PRSS21 20211623 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,fluorescence microscopy ComPPI,IntAct,OmniPath
TANK SERPINB5 24234451 30561431 association virotrap IntAct
IRF6 SERPINB5 16049006 27898060 N/A N/A OmniPath
TP53 SERPINB5 18431400 27898060 stimulant N/A OmniPath
ISG15 SERPINB5 16009940 27898060 N/A N/A OmniPath

Visualization










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