Gene Information gene info

  1. Home

GENE：SLC12A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLC12A2
FullNmae solute carrier family 12 member 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10911
EnsembleID ENSG00000064651
Uniprot P55011

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLC12A2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLC12A2 GO:0005515,GO:0005886,GO:0005886,GO:0006811,GO:0006883,GO:0006884,GO:0006884,GO:0006884,GO:0006972,GO:0007214,GO:0008511,GO:0008511,GO:0008511,GO:0008519,GO:0008519,GO:0009925,GO:0010818,GO:0015079,GO:0015377,GO:0016020,GO:0016323,GO:0016324,GO:0016324,GO:0016328,GO:0019901,GO:0030007,GO:0030321,GO:0030644,GO:0030644,GO:0030659,GO:0031253,GO:0035633,GO:0035633,GO:0035725,GO:0035865,GO:0042995,GO:0043005,GO:0043025,GO:0043025,GO:0044297,GO:0044298,GO:0045795,GO:0046873,GO:0051087,GO:0051879,GO:0055064,GO:0055075,GO:0055078,GO:0061044,GO:0070062,GO:0070634,GO:0071944,GO:0071944,GO:0072488,GO:0098658,GO:0098659,GO:0098719,GO:0150003,GO:0150104,GO:1902476,GO:1902476,GO:1902476,GO:1903561,GO:1904450,GO:1904464,GO:1990573,GO:1990573,GO:1990869

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SLC12A2 hsa:6558 path:hsa04970 Salivary secretion - Homo sapiens (human)
SLC12A2 hsa:6558 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
SLC12A2 hsa:6558 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SLC12A2 OXSR1 20005715 interaction type N/A PSP
SLC12A2 MAPK14 20005715 interaction type N/A PSP
SLC12A2 MAPK14 14563843 20005715 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR SLC12A2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SLC12A2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SLC12A2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SLC12A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC SLC12A2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 SLC12A2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000031E12 SLC12A2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB SLC12A2 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS0000085F64 SLC12A2 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS000076B539 SLC12A2 21572407 25416803 mrna cleavage,inhibition clip,clip TarBase
URS000033EBB8 SLC12A2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STK39 SLC12A2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
OXSR1 SLC12A2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SLC12A2 OXSR1 25361965 interaction type N/A PTMCode2
SLC12A2 STK39 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LGALS3 SLC12A2 25348397 N/A physical interaction ComPPI
HSPA8 SLC12A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
OXSR1 SLC12A2 14525934 16669787 17721439 24234451 25348397 physical association experimental interaction detection,pull down ComPPI,HPRD,IntAct
LGALS9C SLC12A2 25348397 N/A physical interaction ComPPI
MAPK14 SLC12A2 25348397 N/A physical interaction ComPPI
NTRK1 SLC12A2 25348397 N/A physical interaction ComPPI
CANX SLC12A2 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
CDH1 SLC12A2 25348397 N/A physical interaction ComPPI
ILK SLC12A2 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTGIR SLC12A2 25348397 N/A physical interaction ComPPI
EGFR SLC12A2 25348397 N/A physical interaction ComPPI
LGALS8 SLC12A2 25348397 N/A physical interaction ComPPI
COMMD1 SLC12A2 23515529 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CUL7 SLC12A2 25348397 N/A physical interaction ComPPI
SEC13 SLC12A2 25348397 N/A physical interaction ComPPI
CDKN2AIP SLC12A2 25348397 N/A physical interaction ComPPI
STK39 SLC12A2 14525934 14563843 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
TGOLN2 SLC12A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 SLC12A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HTR3A SLC12A2 25348397 N/A physical interaction ComPPI
GNG12 SLC12A2 25348397 N/A physical interaction ComPPI
EZR SLC12A2 22570591 24234451 24555568 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
CTDSPL SLC12A2 25348397 N/A physical interaction ComPPI
FAM189A2 SLC12A2 25348397 N/A physical interaction ComPPI
TMEM216 SLC12A2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
AK1 SLC12A2 25348397 N/A physical interaction ComPPI
LAMP1 SLC12A2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LGALS9 SLC12A2 25348397 N/A physical interaction ComPPI
SLC12A2 ATP4A 25348397 N/A physical interaction ComPPI
SLC12A2 CCDC8 25348397 N/A physical interaction ComPPI
SLC12A2 MCOLN3 25348397 N/A physical interaction ComPPI
SLC12A2 ZACN 25348397 N/A physical interaction ComPPI
SLC12A2 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SLC12A2 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SLC12A2 TMED6 25348397 N/A physical interaction ComPPI
SLC12A2 SLC12A2 10736171 14525934 N/A experimental interaction detection HPRD
SFPQ SLC12A2 24234451 30021884 physical association cross-linking study IntAct
STK39 SLC12A2 12145304 12145305 14563843 16077079 27898060 N/A N/A OmniPath
OXSR1 SLC12A2 12145304 16669787 17721439 20442269 22032326 27898060 inhibition,stimulant N/A OmniPath

Visualization










  Return