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GENE：TFF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TFF1
FullNmae trefoil factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11755
EnsembleID ENSG00000160182
Uniprot P04155

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TFF1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TFF1 GO:0005515,GO:0005576,GO:0005615,GO:0005975,GO:0007165,GO:0008083,GO:0008283,GO:0008285,GO:0010039,GO:0030154,GO:0030277,GO:0035902,GO:0043434

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TFF1 hsa:7031 path:hsa04915 Estrogen signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TFF1 TAB2 12150997 23180781 physical association anti tag coimmunoprecipitation InnateDB
MACROH2A1 TFF1 23180781 24752897 physical association anti tag coimmunoprecipitation InnateDB
PELP1 TFF1 23180781 24752897 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F6 TFF1 12909625 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ESR1 TFF1 10037443 11517191 15541729 16651411 18414489 18543253 21878914 21984905 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator,chromatin immunoprecipitation assay TFlink
ESRRA TFF1 16024613 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 TFF1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 TFF1 10073575 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TFF1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP1 TFF1 15541729 15987735 18543253 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP3 TFF1 15541729 15987735 18543253 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
AURKAIP1 TFF1 21984905 trascriptional regulation,stimulation inferred by curator TFlink
AIP TFF1 21984905 trascriptional regulation,stimulation inferred by curator TFlink
BRCA1 TFF1 11244506 trascriptional regulation,stimulation inferred by curator TFlink
ESR2 TFF1 10037443 11517191 trascriptional regulation,stimulation inferred by curator TFlink
FOXA2 TFF1 10073575 trascriptional regulation,stimulation inferred by curator TFlink
HDAC1 TFF1 19581286 trascriptional regulation,stimulation inferred by curator TFlink
HMGN1 TFF1 17938209 trascriptional regulation,stimulation inferred by curator TFlink
JUN TFF1 12021387 trascriptional regulation,stimulation inferred by curator TFlink
MECP2 TFF1 15870696 trascriptional regulation,stimulation inferred by curator TFlink
MTA1 TFF1 12431981 trascriptional regulation,stimulation inferred by curator TFlink
NCOA4 TFF1 15772083 trascriptional regulation,stimulation inferred by curator TFlink
NELFB TFF1 16452188 17043641 trascriptional regulation,stimulation inferred by curator TFlink
NFATC3 TFF1 16219765 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 TFF1 17565651 trascriptional regulation,stimulation inferred by curator TFlink
RELA TFF1 17565651 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 TFF1 24486742 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00005CC20C TFF1 25015107 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SGTB TFF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFF1 GKN2 14525934 15924415 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
TFF1 UBQLN1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
TFF1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
TFF1 CAVIN1 25348397 N/A physical interaction ComPPI
TFF1 BTN3A1 21982860 24234451 25348397 physical association protein array,surface plasmon resonance,physical interaction ComPPI,IntAct
TFF1 BTNL8 21982860 24234451 25348397 physical association protein array,surface plasmon resonance,physical interaction ComPPI,IntAct
TFF1 CD300LD 21982860 24234451 25348397 physical association protein array,surface plasmon resonance,physical interaction ComPPI,IntAct
TFF1 FCRL4 21982860 24234451 25348397 physical association protein array,surface plasmon resonance,physical interaction ComPPI,IntAct
TFF1 SIGLEC8 21982860 24234451 25348397 physical association protein array,surface plasmon resonance,physical interaction ComPPI,IntAct
TFF1 ZNF250 25348397 N/A physical interaction ComPPI
TFF1 AKT1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 APC 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 ATM 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 ESR2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 FGFR2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 RAD51 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 TSG101 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 XRCC3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TFF1 VSNL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFF1 TFF1 14525934 9355742 N/A experimental interaction detection HPRD
MUC6 TFF1 10673290 14525934 N/A experimental interaction detection HPRD
ESR1 TFF1 27898060 6593703 stimulant N/A OmniPath

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