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GENE：AIMP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AIMP1
FullNmae aminoacyl tRNA synthetase complex interacting multifunctional protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10648
EnsembleID ENSG00000164022
Uniprot Q12904

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AIMP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AIMP1 GO:0000049,GO:0001525,GO:0001937,GO:0005125,GO:0005515,GO:0005615,GO:0005634,GO:0005783,GO:0005794,GO:0005829,GO:0005829,GO:0006412,GO:0006915,GO:0006954,GO:0007165,GO:0007267,GO:0009986,GO:0016020,GO:0017101,GO:0042803,GO:0050900,GO:0051020,GO:0051607,GO:0070094

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AIMP1 HSP90B1 20510162 23180781 physical association anti tag coimmunoprecipitation InnateDB
AIMP1 MAPK8 20510162 23180781 phosphorylation reaction in-gel kinase assay InnateDB
APP AIMP1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 AIMP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 AIMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 AIMP1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000007FBA AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000004CA3 AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003CF1AD AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 AIMP1 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK8 AIMP1 22135298 phosphorylation N/A PhosphoSite
MARS2 AIMP1 25361965 interaction type N/A PTMCode2
AIMP1 MARS2 25361965 interaction type N/A PTMCode2
AIMP2 AIMP1 25361965 interaction type N/A PTMCode2
AIMP1 AIMP2 25361965 interaction type N/A PTMCode2
SMURF2 AIMP1 25361965 interaction type N/A PTMCode2
AIMP1 SMURF2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LENG1 AIMP1 25348397 N/A physical interaction ComPPI
AIMP2 AIMP1 12729910 12819782 14525934 22863883 22939629 24234451 25348397 25416956 26344197 27898060 9878398 physical association experimental interaction detection,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,inference by socio-affinity scoring ComPPI,HPRD,IntAct,OmniPath
TSNAX AIMP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSMC6 AIMP1 25348397 N/A physical interaction ComPPI
PTPN6 AIMP1 25348397 N/A physical interaction ComPPI
KEAP1 AIMP1 25348397 N/A physical interaction ComPPI
OPTN AIMP1 25348397 N/A physical interaction ComPPI
SMURF2 AIMP1 25348397 N/A physical interaction ComPPI
MAPK8 AIMP1 25348397 N/A physical interaction ComPPI
SND1 AIMP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
JUN AIMP1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 AIMP1 25348397 N/A physical interaction ComPPI
EIF4G1 AIMP1 25348397 N/A physical interaction ComPPI
UBC AIMP1 25348397 N/A physical interaction ComPPI
DLD AIMP1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBE2N AIMP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NTRK1 AIMP1 25348397 N/A physical interaction ComPPI
HSP90B1 AIMP1 25348397 N/A physical interaction ComPPI
HNRNPL AIMP1 25348397 N/A physical interaction ComPPI
IQGAP1 AIMP1 14525934 25348397 27898060 9368021 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
PA2G4 AIMP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CFTR AIMP1 25348397 N/A physical interaction ComPPI
CEP135 AIMP1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2S1 AIMP1 25348397 N/A physical interaction ComPPI
PDHA1 AIMP1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SDCBP AIMP1 25348397 N/A physical interaction ComPPI
EPRS1 AIMP1 25348397 N/A physical interaction ComPPI
RARS1 AIMP1 10358004 14525934 17443684 22863883 22939629 24234451 25348397 26344197 27898060 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct,OmniPath
QARS1 AIMP1 25348397 N/A physical interaction ComPPI
TRAP1 AIMP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ARF6 AIMP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPLP0 AIMP1 25348397 N/A physical interaction ComPPI
HOMER1 AIMP1 25348397 N/A physical interaction ComPPI
SNRPD3 AIMP1 25348397 N/A physical interaction ComPPI
CUL1 AIMP1 25348397 N/A physical interaction ComPPI
RPL7A AIMP1 25348397 N/A physical interaction ComPPI
EIF2S3 AIMP1 25348397 N/A physical interaction ComPPI
MARS1 AIMP1 25348397 N/A physical interaction ComPPI
NUBP1 AIMP1 25348397 N/A physical interaction ComPPI
IARS1 AIMP1 25348397 N/A physical interaction ComPPI
PTBP1 AIMP1 25348397 N/A physical interaction ComPPI
TWF1 AIMP1 25348397 N/A physical interaction ComPPI
KARS1 AIMP1 17443684 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF4A2 AIMP1 25348397 N/A physical interaction ComPPI
BRCA1 AIMP1 25348397 N/A physical interaction ComPPI
MCFD2 AIMP1 25348397 N/A physical interaction ComPPI
RPL23A AIMP1 25348397 N/A physical interaction ComPPI
RPL13 AIMP1 25348397 N/A physical interaction ComPPI
PSMA7 AIMP1 25348397 N/A physical interaction ComPPI
TGOLN2 AIMP1 24234451 25348397 29568061 association pull down ComPPI,IntAct
DNAJA1 AIMP1 25348397 N/A physical interaction ComPPI
BET1 AIMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IKBKE AIMP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAN2 AIMP1 25348397 N/A physical interaction ComPPI
STYX AIMP1 25348397 N/A physical interaction ComPPI
DARS1 AIMP1 25348397 N/A physical interaction ComPPI
EEF1E1 AIMP1 25348397 N/A physical interaction ComPPI
MCC AIMP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CYLD AIMP1 25348397 N/A physical interaction ComPPI
TRIR AIMP1 25348397 N/A physical interaction ComPPI
CIAPIN1 AIMP1 25348397 N/A physical interaction ComPPI
RPL36 AIMP1 25348397 N/A physical interaction ComPPI
RPL21 AIMP1 25348397 N/A physical interaction ComPPI
OFD1 AIMP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RPL17 AIMP1 25348397 N/A physical interaction ComPPI
RPL15 AIMP1 25348397 N/A physical interaction ComPPI
VARS1 AIMP1 25348397 N/A physical interaction ComPPI
LARS1 AIMP1 25348397 N/A physical interaction ComPPI
APP AIMP1 25348397 N/A physical interaction ComPPI
HLA-B AIMP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCAR2 AIMP1 25348397 N/A physical interaction ComPPI
EIF2S3B AIMP1 25348397 N/A physical interaction ComPPI
GCC2 AIMP1 25348397 N/A physical interaction ComPPI
ATP6V1F AIMP1 25348397 N/A physical interaction ComPPI
RPLP0P6 AIMP1 25348397 N/A physical interaction ComPPI
AIMP1 RPL27A 25348397 N/A physical interaction ComPPI
AIMP1 CORO1C 25348397 N/A physical interaction ComPPI
AIMP1 TARS3 25348397 N/A physical interaction ComPPI
AIMP1 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
AIMP1 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GOLPH3 AIMP1 25348397 N/A physical interaction ComPPI
COMTD1 AIMP1 25348397 N/A physical interaction ComPPI
AIMP1 MAPK14 14525934 9878398 N/A two hybrid HPRD
AIMP1 AIMP1 10852899 14525934 N/A experimental interaction detection HPRD
AIMP1 ATP5F1A 11741979 14525934 N/A experimental interaction detection HPRD
SMARCB1 AIMP1 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct
STK38L AIMP1 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct
HSP90B1 AIMP1 20510162 27898060 N/A N/A OmniPath
MAPK8 AIMP1 20510162 27898060 inhibition N/A OmniPath
AIMP1 SMURF2 18448069 27898060 stimulant N/A OmniPath

Visualization










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