Gene Information gene info

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GENE：C6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C6
FullNmae complement C6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1339
EnsembleID ENSG00000039537
Uniprot P13671

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C6 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
C6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C6 GO:0001701,GO:0005515,GO:0005576,GO:0005579,GO:0005579,GO:0005579,GO:0005615,GO:0005886,GO:0006956,GO:0006956,GO:0006958,GO:0031640,GO:0045087,GO:0050778,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C6 hsa:729 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C6 hsa:729 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
C6 hsa:729 path:hsa05020 Prion disease - Homo sapiens (human)
C6 hsa:729 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C6 hsa:729 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 C6 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 C6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA C6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF C6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 C6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF C6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 C6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001DE669 C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 C6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 C6 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
C5 C6 25361965 interaction type N/A PTMCode2
C6 C5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK1 C6 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 C6 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
F2 C6 14525934 25348397 27898060 3192535 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
C6 OGA 14525934 16169070 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
C6 FN1 25348397 N/A physical interaction ComPPI
C6 SART3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
C6 FUS 25348397 N/A physical interaction ComPPI
C6 DPY19L3 25348397 N/A physical interaction ComPPI
C6 ACOT9 25348397 N/A physical interaction ComPPI
C6 B3GLCT 25348397 N/A physical interaction ComPPI
C6 ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
C6 FYN 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
C5 C6 1387399 14525934 25348397 2808363 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD

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